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Protein

Phosphosulfolactate synthase

Gene

yitD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis of L-sulfolactate, which is a major constituent of sporulating cells and mature spores.By similarity

Catalytic activityi

(2R)-2-O-phospho-3-sulfolactate = phosphoenolpyruvate + hydrogen sulfite.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciBSUB:BSU10950-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphosulfolactate synthase (EC:4.4.1.19)
Alternative name(s):
(2R)-phospho-3-sulfolactate synthase
Short name:
PSL synthase
Gene namesi
Name:yitD
Ordered Locus Names:BSU10950
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 252252Phosphosulfolactate synthasePRO_0000080832Add
BLAST

Proteomic databases

PaxDbiO06739.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006046.

Structurei

Secondary structure

1
252
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi17 – 193Combined sources
Beta strandi21 – 277Combined sources
Helixi30 – 4011Combined sources
Helixi41 – 433Combined sources
Beta strandi46 – 494Combined sources
Helixi53 – 564Combined sources
Helixi60 – 6910Combined sources
Beta strandi73 – 764Combined sources
Helixi78 – 869Combined sources
Helixi90 – 9910Combined sources
Beta strandi103 – 1075Combined sources
Beta strandi110 – 1123Combined sources
Helixi116 – 12611Combined sources
Turni127 – 1293Combined sources
Beta strandi130 – 1356Combined sources
Helixi151 – 16212Combined sources
Beta strandi164 – 1696Combined sources
Helixi191 – 1955Combined sources
Turni196 – 1983Combined sources
Helixi201 – 2033Combined sources
Beta strandi204 – 2074Combined sources
Helixi211 – 22111Combined sources
Beta strandi227 – 2315Combined sources
Helixi232 – 2343Combined sources
Helixi235 – 2428Combined sources
Helixi247 – 2493Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1U83X-ray2.20A1-252[»]
ProteinModelPortaliO06739.
SMRiO06739. Positions 3-251.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO06739.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41061P3. Bacteria.
COG1809. LUCA.
HOGENOMiHOG000223610.
InParanoidiO06739.
KOiK08097.
OMAiNLANISF.
PhylomeDBiO06739.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR003830. ComA_synth.
[Graphical view]
PfamiPF02679. ComA. 1 hit.
[Graphical view]
SUPFAMiSSF102110. SSF102110. 1 hit.

Sequencei

Sequence statusi: Complete.

O06739-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDFSLELPV RTNKPRETGQ SILIDNGYPL QFFKDAIAGA SDYIDFVKFG
60 70 80 90 100
WGTSLLTKDL EEKISTLKEH DITFFFGGTL FEKYVSQKKV NEFHRYCTYF
110 120 130 140 150
GCEYIEISNG TLPMTNKEKA AYIADFSDEF LVLSEVGSKD AELASRQSSE
160 170 180 190 200
EWLEYIVEDM EAGAEKVITE ARESGTGGIC SSSGDVRFQI VDDIISSDID
210 220 230 240 250
INRLIFEAPN KTLQQGFIQK IGPNVNLANI PFHDAIALET LRLGLRSDTF

FL
Length:252
Mass (Da):28,357
Last modified:July 1, 1997 - v1
Checksum:i7904A18AF982C970
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09476 Genomic DNA. Translation: CAA70659.1.
AL009126 Genomic DNA. Translation: CAB12935.1.
PIRiE69839.
RefSeqiNP_388976.1. NC_000964.3.
WP_003233048.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12935; CAB12935; BSU10950.
GeneIDi939794.
KEGGibsu:BSU10950.
PATRICi18973896. VBIBacSub10457_1142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09476 Genomic DNA. Translation: CAA70659.1.
AL009126 Genomic DNA. Translation: CAB12935.1.
PIRiE69839.
RefSeqiNP_388976.1. NC_000964.3.
WP_003233048.1. NZ_JNCM01000035.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1U83X-ray2.20A1-252[»]
ProteinModelPortaliO06739.
SMRiO06739. Positions 3-251.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006046.

Proteomic databases

PaxDbiO06739.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12935; CAB12935; BSU10950.
GeneIDi939794.
KEGGibsu:BSU10950.
PATRICi18973896. VBIBacSub10457_1142.

Phylogenomic databases

eggNOGiENOG41061P3. Bacteria.
COG1809. LUCA.
HOGENOMiHOG000223610.
InParanoidiO06739.
KOiK08097.
OMAiNLANISF.
PhylomeDBiO06739.

Enzyme and pathway databases

BioCyciBSUB:BSU10950-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO06739.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR003830. ComA_synth.
[Graphical view]
PfamiPF02679. ComA. 1 hit.
[Graphical view]
SUPFAMiSSF102110. SSF102110. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPSLS_BACSU
AccessioniPrimary (citable) accession number: O06739
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.