Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphosulfolactate synthase

Gene

yitD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis of L-sulfolactate, which is a major constituent of sporulating cells and mature spores.By similarity

Catalytic activityi

(2R)-2-O-phospho-3-sulfolactate = phosphoenolpyruvate + hydrogen sulfite.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciBSUB:BSU10950-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphosulfolactate synthase (EC:4.4.1.19)
Alternative name(s):
(2R)-phospho-3-sulfolactate synthase
Short name:
PSL synthase
Gene namesi
Name:yitD
Ordered Locus Names:BSU10950
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000808321 – 252Phosphosulfolactate synthaseAdd BLAST252

Proteomic databases

PaxDbiO06739.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006046.

Structurei

Secondary structure

1252
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi17 – 19Combined sources3
Beta strandi21 – 27Combined sources7
Helixi30 – 40Combined sources11
Helixi41 – 43Combined sources3
Beta strandi46 – 49Combined sources4
Helixi53 – 56Combined sources4
Helixi60 – 69Combined sources10
Beta strandi73 – 76Combined sources4
Helixi78 – 86Combined sources9
Helixi90 – 99Combined sources10
Beta strandi103 – 107Combined sources5
Beta strandi110 – 112Combined sources3
Helixi116 – 126Combined sources11
Turni127 – 129Combined sources3
Beta strandi130 – 135Combined sources6
Helixi151 – 162Combined sources12
Beta strandi164 – 169Combined sources6
Helixi191 – 195Combined sources5
Turni196 – 198Combined sources3
Helixi201 – 203Combined sources3
Beta strandi204 – 207Combined sources4
Helixi211 – 221Combined sources11
Beta strandi227 – 231Combined sources5
Helixi232 – 234Combined sources3
Helixi235 – 242Combined sources8
Helixi247 – 249Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1U83X-ray2.20A1-252[»]
ProteinModelPortaliO06739.
SMRiO06739.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO06739.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41061P3. Bacteria.
COG1809. LUCA.
HOGENOMiHOG000223610.
InParanoidiO06739.
KOiK08097.
OMAiNLANISF.
PhylomeDBiO06739.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR003830. ComA_synth.
[Graphical view]
PfamiPF02679. ComA. 1 hit.
[Graphical view]
SUPFAMiSSF102110. SSF102110. 1 hit.

Sequencei

Sequence statusi: Complete.

O06739-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDFSLELPV RTNKPRETGQ SILIDNGYPL QFFKDAIAGA SDYIDFVKFG
60 70 80 90 100
WGTSLLTKDL EEKISTLKEH DITFFFGGTL FEKYVSQKKV NEFHRYCTYF
110 120 130 140 150
GCEYIEISNG TLPMTNKEKA AYIADFSDEF LVLSEVGSKD AELASRQSSE
160 170 180 190 200
EWLEYIVEDM EAGAEKVITE ARESGTGGIC SSSGDVRFQI VDDIISSDID
210 220 230 240 250
INRLIFEAPN KTLQQGFIQK IGPNVNLANI PFHDAIALET LRLGLRSDTF

FL
Length:252
Mass (Da):28,357
Last modified:July 1, 1997 - v1
Checksum:i7904A18AF982C970
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09476 Genomic DNA. Translation: CAA70659.1.
AL009126 Genomic DNA. Translation: CAB12935.1.
PIRiE69839.
RefSeqiNP_388976.1. NC_000964.3.
WP_003233048.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12935; CAB12935; BSU10950.
GeneIDi939794.
KEGGibsu:BSU10950.
PATRICi18973896. VBIBacSub10457_1142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09476 Genomic DNA. Translation: CAA70659.1.
AL009126 Genomic DNA. Translation: CAB12935.1.
PIRiE69839.
RefSeqiNP_388976.1. NC_000964.3.
WP_003233048.1. NZ_JNCM01000035.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1U83X-ray2.20A1-252[»]
ProteinModelPortaliO06739.
SMRiO06739.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006046.

Proteomic databases

PaxDbiO06739.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12935; CAB12935; BSU10950.
GeneIDi939794.
KEGGibsu:BSU10950.
PATRICi18973896. VBIBacSub10457_1142.

Phylogenomic databases

eggNOGiENOG41061P3. Bacteria.
COG1809. LUCA.
HOGENOMiHOG000223610.
InParanoidiO06739.
KOiK08097.
OMAiNLANISF.
PhylomeDBiO06739.

Enzyme and pathway databases

BioCyciBSUB:BSU10950-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO06739.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR003830. ComA_synth.
[Graphical view]
PfamiPF02679. ComA. 1 hit.
[Graphical view]
SUPFAMiSSF102110. SSF102110. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPSLS_BACSU
AccessioniPrimary (citable) accession number: O06739
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: July 1, 1997
Last modified: November 2, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.