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Protein
Submitted name:

Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2

Gene

gnd2

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • growth Source: MTBBASE
  • pentose-phosphate shunt Source: InterPro

Names & Taxonomyi

Protein namesi
Submitted name:
Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2Imported
Gene namesi
Name:gnd2Imported
Ordered Locus Names:Rv1122Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1122.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: MTBBASE

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1122.

Structurei

3D structure databases

SMRiO06574.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108J5G. Bacteria.
COG1023. LUCA.
HOGENOMiHOG000255146.
KOiK00033.
OMAiPEYYQYD.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR004849. 6DGDH_YqeC.
IPR013328. 6PGD_dom_2.
IPR006114. 6PGDH_C.
IPR006115. 6PGDH_NADP-bd.
IPR016040. NAD(P)-bd_dom.
IPR006183. Pgluconate_DH.
PfamiView protein in Pfam
PF00393. 6PGD. 2 hits.
PF03446. NAD_binding_2. 1 hit.
PRINTSiPR00076. 6PGDHDRGNASE.
SMARTiView protein in SMART
SM01350. 6PGD. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR00872. gnd_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

O06574-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLGMIGLGR MGANIVRRLA KGGHDCVVYD HDPDAVKAMA GEDRTTGVAS
60 70 80 90 100
LRELSQRLSA PRVVWVMVPA GNITTAVIEE LANTLEAGDI VIDGGNTYYR
110 120 130 140 150
DDLRHEKLLF KKGIHLLDCG TSGGVWGRER GYCLMIGGDG DAFARAEPIF
160 170 180 190 200
ATVAPGVAAA PRTPGRDGEV APSEQGYLHC GPCGSGHFVK MVHNGIEYGM
210 220 230 240 250
MASLAEGLNI LRNADVGTRV QHGDAETAPL PNPECYQYDF DIPEVAEVWR
260 270 280 290 300
RGSVIGSWLL DLTAIALRES PDLAEFSGRV SDSGEGRWTA IAAIDEGVPA
310 320 330 340
PVLTTALQSR FASRDLDDFA NKALSAMRKQ FGGHAEKPAN
Length:340
Mass (Da):36,358
Last modified:July 1, 1997 - v1
Checksum:iFC8A3856FBEE6D50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43876.1.
RefSeqiNP_215638.1. NC_000962.3.
WP_003405880.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR13867; AIR13867; LH57_06165.
CCP43876; CCP43876; Rv1122.
GeneIDi885820.
KEGGimtu:Rv1122.
mtv:RVBD_1122.
PATRICifig|83332.111.peg.1252.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO06574_MYCTU
AccessioniPrimary (citable) accession number: O06574
Secondary accession number(s): F2GGF0, I6X0D5, Q7D8T5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: June 7, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported