Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

GTP-binding protein TypA

Gene

typA

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorImported

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5334-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
GTP-binding protein TypAImported
Submitted name:
Possible GTP-binding translation elongation factor TypA (Tyrosine phosphorylated protein A) (GTP-binding protein)Imported
Gene namesi
Name:typAImported
Ordered Locus Names:Rv1165Imported
ORF Names:LH57_06410Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1165.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • intracellular Source: GO_Central
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1165.

Structurei

3D structure databases

ProteinModelPortaliO06563.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 215Tr-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST215

Phylogenomic databases

eggNOGiENOG4105CI3. Bacteria.
COG1217. LUCA.
HOGENOMiHOG000282351.
KOiK06207.
OMAiSMLFTIN.
PhylomeDBiO06563.

Family and domain databases

Gene3Di3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR004161. EFTu-like_2.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR006298. TypA_GTP-bd.
[Graphical view]
PANTHERiPTHR23115:SF14. PTHR23115:SF14. 2 hits.
PfamiPF00679. EFG_C. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
TIGR01394. TypA_BipA. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O06563-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFRNVAIVA HVDHGKTTLV DAMLRQSGAL RERGELQERV MDTGDLEREK
60 70 80 90 100
GITILAKNTA VHRHHPDGTV TVINVIDTPG HADFGGEVER GLSMVDGVLL
110 120 130 140 150
LVDASEGPLP QTRFVLRKAL AAHLPVILVV NKTDRPDARI AEVVDASHDL
160 170 180 190 200
LLDVASDLDD EAAAAAEHAL GLPTLYASGR AGVASTTAPP DGQVPDGTNL
210 220 230 240 250
DPLFEVLEKH VPPPKGEPDA PLQALVTNLD ASTFLGRLAL IRIYNGRIRK
260 270 280 290 300
GQQVAWIRQV DGQQTVTTAK ITELLATEGV ERKPTDAAVA GDIVAVAGLP
310 320 330 340 350
EIMIGDTLAA SANPVALPRI TVDEPAISVT IGTNTSPLAG KVGGHKLTAR
360 370 380 390 400
MVRSRLDAEL VGNVSIRVVD IGAPDAWEVQ GRGELALAVL VEQMRREGFE
410 420 430 440 450
LTVGKPQVVT KTIDGTLHEP FESMTVDCPE EYIGAVTQLM AARKGRMVEM
460 470 480 490 500
ANHTTGWVRM DFVVPSRGLI GWRTDFLTET RGSGVGHAVF DGYRPWAGEI
510 520 530 540 550
RARHTGSLVS DRAGAITPFA LLQLADRGQF FVEPGQQTYE GMVVGINPRP
560 570 580 590 600
EDLDINVTRE KKLTNMRSST ADVIETLAKP LQLDLERAME LCAPDECVEV
610 620
TPEIVRIRKV ELAAAARARS RARTKARG
Length:628
Mass (Da):67,580
Last modified:August 1, 1998 - v2
Checksum:i2C0483B2539E7113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13913.1.
AL123456 Genomic DNA. Translation: CCP43921.1.
RefSeqiNP_215681.1. NC_000962.3.
WP_003406099.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR13913; AIR13913; LH57_06410.
CCP43921; CCP43921; Rv1165.
GeneIDi886038.
KEGGimtu:Rv1165.
mtv:RVBD_1165.
PATRICi18124414. VBIMycTub22151_1326.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13913.1.
AL123456 Genomic DNA. Translation: CCP43921.1.
RefSeqiNP_215681.1. NC_000962.3.
WP_003406099.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliO06563.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1165.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR13913; AIR13913; LH57_06410.
CCP43921; CCP43921; Rv1165.
GeneIDi886038.
KEGGimtu:Rv1165.
mtv:RVBD_1165.
PATRICi18124414. VBIMycTub22151_1326.

Organism-specific databases

TubercuListiRv1165.

Phylogenomic databases

eggNOGiENOG4105CI3. Bacteria.
COG1217. LUCA.
HOGENOMiHOG000282351.
KOiK06207.
OMAiSMLFTIN.
PhylomeDBiO06563.

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5334-MONOMER.

Family and domain databases

Gene3Di3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR004161. EFTu-like_2.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR006298. TypA_GTP-bd.
[Graphical view]
PANTHERiPTHR23115:SF14. PTHR23115:SF14. 2 hits.
PfamiPF00679. EFG_C. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
TIGR01394. TypA_BipA. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO06563_MYCTU
AccessioniPrimary (citable) accession number: O06563
Secondary accession number(s): F2GG22, I6XAT8, Q7D8Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 142 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.