UniProtKB - O06543 (O06543_MYCTU)
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Protein
Submitted name:
Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )
Gene
mcr
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
GO - Molecular functioni
- alpha-methylacyl-CoA racemase activity Source: MTBBASE
- protein homodimerization activity Source: MTBBASE
GO - Biological processi
- acyl-CoA metabolic process Source: MTBBASE
Enzyme and pathway databases
BioCyci | MetaCyc:G185E-5310-MONOMER. |
BRENDAi | 5.1.99.4. 3445. |
Chemistry databases
SwissLipidsi | SLP:000001290. |
Names & Taxonomyi
Protein namesi | Submitted name: Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )Imported |
Gene namesi | Name:mcrImported Ordered Locus Names:Rv1143Imported |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Interactioni
GO - Molecular functioni
- protein homodimerization activity Source: MTBBASE
Protein-protein interaction databases
STRINGi | 83332.Rv1143. |
Structurei
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1X74 | X-ray | 1.79 | A/B/C/D | 1-360 | [»] | |
2GCE | X-ray | 1.85 | A/B/C/D | 1-360 | [»] | |
2GCI | X-ray | 1.60 | A/B/C/D | 1-360 | [»] | |
2GD0 | X-ray | 1.70 | A/B/C/D | 1-360 | [»] | |
2GD2 | X-ray | 1.70 | A/B/C/D | 1-360 | [»] | |
2GD6 | X-ray | 2.30 | A/B/C/D | 1-360 | [»] | |
2YIM | X-ray | 1.41 | A/B/C/D | 1-360 | [»] | |
SMRi | O06543. | |||||
ModBasei | Search... | |||||
MobiDBi | Search... |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG4105C04. Bacteria. COG1804. LUCA. |
HOGENOMi | HOG000219744. |
KOi | K01796. |
OMAi | YVASWLF. |
Family and domain databases
Gene3Di | 3.40.50.10540. 1 hit. |
InterProi | View protein in InterPro IPR003673. CoA-Trfase_fam_III. IPR023606. CoA-Trfase_III_dom_sf. |
Pfami | View protein in Pfam PF02515. CoA_transf_3. 1 hit. |
SUPFAMi | SSF89796. SSF89796. 1 hit. |
i Sequence
Sequence statusi: Complete.
O06543-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGPLSGLRV VELAGIGPGP HAAMILGDLG ADVVRIDRPS SVDGISRDAM
60 70 80 90 100
LRNRRIVTAD LKSDQGLELA LKLIAKADVL IEGYRPGVTE RLGLGPEECA
110 120 130 140 150
KVNDRLIYAR MTGWGQTGPR SQQAGHDINY ISLNGILHAI GRGDERPVPP
160 170 180 190 200
LNLVGDFGGG SMFLLVGILA ALWERQSSGK GQVVDAAMVD GSSVLIQMMW
210 220 230 240 250
AMRATGMWTD TRGANMLDGG APYYDTYECA DGRYVAVGAI EPQFYAAMLA
260 270 280 290 300
GLGLDAAELP PQNDRARWPE LRALLTEAFA SHDRDHWGAV FANSDACVTP
310 320 330 340 350
VLAFGEVHNE PHIIERNTFY EANGGWQPMP APRFSRTASS QPRPPAATID
360
IEAVLTDWDG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA. Translation: CCP43898.1. |
RefSeqi | NP_215659.1. NC_000962.3. WP_003898740.1. NZ_KK339370.1. |
Genome annotation databases
EnsemblBacteriai | AIR13889; AIR13889; LH57_06275. CCP43898; CCP43898; Rv1143. |
GeneIDi | 885067. |
KEGGi | mtu:Rv1143. mtv:RVBD_1143. |
PATRICi | fig|83332.111.peg.1277. |
Similar proteinsi
Entry informationi
Entry namei | O06543_MYCTU | |
Accessioni | O06543Primary (citable) accession number: O06543 Secondary accession number(s): I6XAR5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 1997 |
Last sequence update: | July 5, 2004 | |
Last modified: | January 31, 2018 | |
This is version 115 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |