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Protein

Putative aldehyde dehydrogenase YfmT

Gene

yfmT

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei253 – 2531PROSITE-ProRule annotation
Active sitei287 – 2871PROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi231 – 2366NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciBSUB:BSU07350-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase YfmT (EC:1.2.1.3)
Gene namesi
Name:yfmT
Ordered Locus Names:BSU07350
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570 Componenti: Chromosome

Organism-specific databases

GenoListiBSU07350.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Putative aldehyde dehydrogenase YfmTPRO_0000379510Add
BLAST

Proteomic databases

PaxDbiO06478.

Expressioni

Inductioni

Transcriptionally regulated by SigD; part of the yfmT/yfmS operon.1 Publication

Interactioni

Protein-protein interaction databases

IntActiO06478. 1 interaction.
MINTiMINT-8366079.
STRINGi224308.Bsubs1_010100004118.

Structurei

3D structure databases

ProteinModelPortaliO06478.
SMRiO06478. Positions 8-465.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271509.
InParanoidiO06478.
KOiK00128.
OMAiATFPVRM.
OrthoDBiEOG6BS8QW.
PhylomeDBiO06478.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O06478-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQYEELNKQ FIGGKWQEGS SPNVLENKNP YTQKTFTTFR KATADDVDEA
60 70 80 90 100
YRAAALAKKK WDAVNPFEKR TILEKAVTYI EENEEAIIYL IMEELGGTRL
110 120 130 140 150
KAAFEIGLVK NIIKEAATFP IRMEGKILPS TIDGKENRLY RVPAGVVGVI
160 170 180 190 200
SPFNFPFFLS MKSVAPALGA GNGVVLKPHE ETPICGGTLI AKIFENAGIP
210 220 230 240 250
AGLLNVVVTD IAEIGDSFVE HPVPRIISFT GSTKVGSYIG QLAMKHFKKP
260 270 280 290 300
LLELGGNSAF IVLEDADIEY AVNAAVFSRF THQGQICMSA NRVLVHSSIY
310 320 330 340 350
DKFLELYQAK VESLKVGDPM DPDTIIGPLI NSRQTDGLMK TVEQAIEEGA
360 370 380 390 400
VPVKLGGFNG TIVEPTILKD VKPFMSIAKE ELFGPVVSFM KFDSEDEAVD
410 420 430 440 450
IANETPFGLS GAVHTSNLER GVAFAKRIET GMIHVNDTTI NDEPNVAFGG
460 470 480
EKQSGLGRLN GEWSLEEFTT LKWISVQHEK RSFPY
Length:485
Mass (Da):53,321
Last modified:July 1, 1997 - v1
Checksum:iC87E9AA12C704B68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86418 Genomic DNA. Translation: BAA20109.1.
AL009126 Genomic DNA. Translation: CAB12554.1.
PIRiC69814.
RefSeqiNP_388616.1. NC_000964.3.
WP_003244104.1. NZ_JNCM01000032.1.

Genome annotation databases

EnsemblBacteriaiCAB12554; CAB12554; BSU07350.
GeneIDi938788.
KEGGibsu:BSU07350.
PATRICi18973120. VBIBacSub10457_0774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86418 Genomic DNA. Translation: BAA20109.1.
AL009126 Genomic DNA. Translation: CAB12554.1.
PIRiC69814.
RefSeqiNP_388616.1. NC_000964.3.
WP_003244104.1. NZ_JNCM01000032.1.

3D structure databases

ProteinModelPortaliO06478.
SMRiO06478. Positions 8-465.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO06478. 1 interaction.
MINTiMINT-8366079.
STRINGi224308.Bsubs1_010100004118.

Proteomic databases

PaxDbiO06478.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12554; CAB12554; BSU07350.
GeneIDi938788.
KEGGibsu:BSU07350.
PATRICi18973120. VBIBacSub10457_0774.

Organism-specific databases

GenoListiBSU07350.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271509.
InParanoidiO06478.
KOiK00128.
OMAiATFPVRM.
OrthoDBiEOG6BS8QW.
PhylomeDBiO06478.

Enzyme and pathway databases

BioCyciBSUB:BSU07350-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A 23.4 kb segment at the 69 degrees-70 degrees region of the Bacillus subtilis genome."
    Yamamoto H., Uchiyama S., Nugroho F.A., Sekiguchi J.
    Microbiology 143:1317-1320(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / AC327.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  3. "Systematic analysis of SigD-regulated genes in Bacillus subtilis by DNA microarray and Northern blotting analyses."
    Serizawa M., Yamamoto H., Yamaguchi H., Fujita Y., Kobayashi K., Ogasawara N., Sekiguchi J.
    Gene 329:125-136(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, OPERON STRUCTURE.
    Strain: 168.

Entry informationi

Entry nameiALDH5_BACSU
AccessioniPrimary (citable) accession number: O06478
Secondary accession number(s): Q797A6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: July 1, 1997
Last modified: July 22, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.