O06441 (O06441_RHOSO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Heroin esterase EMBL AAC45283.1

Gene names

Name:

her EMBL AAC45283.1

Organism

Rhodococcus sp. EMBL AAC45283.1

Taxonomic identifier

1831 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1LZK PDB 1LZL
Gene Ontology (GO)
Molecular function	hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O06441 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 93B01D5C760B4A1E	FASTA	322	34,240
	10 20 30 40 50 60 MTTFPTLDPE LAAALTMLPK VDFADLPNAR ATYDALIGAM LADLSFDGVS LRELSAPGLD 70 80 90 100 110 120 GDPEVKIRFV TPDNTAGPVP VLLWIHGGGF AIGTAESSDP FCVEVARELG FAVANVEYRL 130 140 150 160 170 180 APETTFPGPV NDCYAALLYI HAHAEELGID PSRIAVGGES AGGGLAAGTV LKARDEGVVP 190 200 210 220 230 240 VAFQFLEIPE LDDRLETVSM TNFVDTPLWH RPNAILSWKY YLGESYSGPE DPDVSIYAAP 250 260 270 280 290 300 SRATDLTGLP PTYLSTMELD PLRDEGIEYA LRLLQAGVSV ELHSFPGTFH GSALVATAGV 310 320 RERGAAKPHC DPERVAFAVA VS

References

[1]	"Molecular analysis of the Rhodococcus sp. strain H1 her gene and characterization of its product, a heroin esterase, expressed in Escherichia coli." Rathbone D.A., Holt P.J., Lowe C.R., Bruce N.C. Appl. Environ. Microbiol. 63:2062-2066(1997) [PubMed: 9143135] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H1 EMBL AAC45283.1.
[2]	"Observation of an arsenic adduct in an acetyl esterase crystal structure." Zhu X., Larsen N.A., Basran A., Bruce N.C., Wilson I.A. J. Biol. Chem. 278:2008-2014(2003) [PubMed: 12421810] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) OF 1-306.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U70619 Genomic DNA. Translation: AAC45283.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1LZK	X-ray	1.45	A	1-306	[»]
1LZL	X-ray	1.30	A	1-306	[»]

ProteinModelPortal

O06441.

SMR

O06441. Positions 2-307.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Family and domain databases

InterPro

IPR013094. AB_hydrolase_3.
[Graphical view]

Pfam

PF07859. Abhydrolase_3. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

O06441_RHOSO

Accession

Primary (citable) accession number: O06441

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	May 31, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)