Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-1986-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:NE1949
OrganismiNitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Taxonomic identifieri228410 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
Proteomesi
  • UP000001416 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 644644Chaperone protein DnaKPRO_0000078504Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei199 – 1991Phosphothreonine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiO06430.

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

Protein-protein interaction databases

STRINGi228410.NE1949.

Structurei

3D structure databases

ProteinModelPortaliO06430.
SMRiO06430. Positions 1-607.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.
PhylomeDBiO06430.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O06430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIIGIDLG TTNSCVAVME GNKPKVIENA EGARTTPSIV AYAEDNEILV
60 70 80 90 100
GASAKRQAVT NPENTLFAIK RLIGRRFDEE VVQKDISVTP YKIVRADNND
110 120 130 140 150
AWIEARGRKI APPEVSAQVL IKMKKTAEDY LGEPVTEAVI TVPAYFNDSQ
160 170 180 190 200
RQATKDAGRI AGLEVKRIIN EPTAAALAFG LDKKEGDRKI AVYDLGGGTF
210 220 230 240 250
DISIIEIAEV EGEHQFEVLA TNGDTFLGGE DFDSRVIEYL VDEFRKESGI
260 270 280 290 300
DLKKDMLALQ RLKDAAEKAK IELSSSQQTE VNLPYITADA SGPKHLAVKI
310 320 330 340 350
TRAKLESLVE ELIERTAGPC RTALKDAGLS VSDINDVILV GGQTRMPKVQ
360 370 380 390 400
EKVKEIFGKE PRKDVNPDEA VAIGAAIQGG VLKGDVKDVL LLDVTPLSLG
410 420 430 440 450
IETLGGVMTK LIQKNTTIPT KAQQVFSTAD DNQTAVTIHV LQGEREVASG
460 470 480 490 500
NKSLGQFNLT DIPSAPRGMP QIEVIFDIDA NGILHVSAKD KATGKENKIK
510 520 530 540 550
IQASSGLSED EIQKMVKDAE AHAEEDKKAL DLVNSRNQCD AMIHSVRKSL
560 570 580 590 600
AEYGDKLEGD EKSRIEAALK EAEEALKSGD KQTIDAKTQA LTEASHKLAE
610 620 630 640
KMYAQEQAQA GQQAGAGTAS DQSQDKPVEG EVVDAEFEEV KDKK
Length:644
Mass (Da):69,695
Last modified:July 1, 1997 - v1
Checksum:i8E8EF50CE3E5D71C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB018706 Genomic DNA. Translation: BAA33935.1.
AL954747 Genomic DNA. Translation: CAD85860.1.
RefSeqiWP_011112481.1. NC_004757.1.

Genome annotation databases

EnsemblBacteriaiCAD85860; CAD85860; NE1949.
KEGGineu:NE1949.
PATRICi22715203. VBINitEur56163_2187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB018706 Genomic DNA. Translation: BAA33935.1.
AL954747 Genomic DNA. Translation: CAD85860.1.
RefSeqiWP_011112481.1. NC_004757.1.

3D structure databases

ProteinModelPortaliO06430.
SMRiO06430. Positions 1-607.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi228410.NE1949.

Proteomic databases

PRIDEiO06430.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD85860; CAD85860; NE1949.
KEGGineu:NE1949.
PATRICi22715203. VBINitEur56163_2187.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.
PhylomeDBiO06430.

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-1986-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_NITEU
AccessioniPrimary (citable) accession number: O06430
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.