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O06362

- O06362_MYCTO

UniProt

O06362 - O06362_MYCTO

Protein
Submitted name:

Adenylate cyclase

Gene

MT3748

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: MTBBASE
    2. signal transducer activity Source: InterPro

    GO - Biological processi

    1. ATP catabolic process Source: MTBBASE
    2. cAMP biosynthetic process Source: GOC
    3. cAMP catabolic process Source: MTBBASE
    4. intracellular signal transduction Source: InterPro

    Enzyme and pathway databases

    BioCyciMTBRV:RV3645-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adenylate cyclaseImported
    Submitted name:
    Adenylate cyclase, putativeImported
    Gene namesi
    Ordered Locus Names:MT3748Imported
    ORF Names:V735_03781Imported
    OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
    Taxonomic identifieri83331 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000001020: Chromosome

    Organism-specific databases

    TubercuListiRv3645.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi83332.Rv3645.

    Structurei

    3D structure databases

    SMRiO06362. Positions 282-542.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000045754.
    KOiK01768.
    OMAiVHRNKGI.
    OrthoDBiEOG6HXJ1J.

    Family and domain databases

    Gene3Di3.30.70.1230. 1 hit.
    InterProiIPR001054. A/G_cyclase.
    IPR003660. HAMP_linker_domain.
    [Graphical view]
    PfamiPF00211. Guanylate_cyc. 1 hit.
    PF00672. HAMP. 1 hit.
    [Graphical view]
    SMARTiSM00044. CYCc. 1 hit.
    SM00304. HAMP. 1 hit.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 1 hit.
    PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O06362-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAEAFVGFR QVPAARYGGL MATTAALPRR IHAFVRWVVR TPWPLFSLSM    50
    LQSDIIGALF VLGFLRYGLP PQDNIQLQDL PPVNLLIFVS TVIILFLAGA 100
    VVNLKLLMPV FRWQRRDNLL TEPDPAATEL ARSRALRMPL YRTLISLAVW 150
    ATGGGVFILA SWSVAKHAAP VVAVATALGA TATAIIGYLQ SERVLRPVAV 200
    AALRSGVPEN VNAPGVILRL MLAWIPSTGV PLLAIVLAVA ADKIALLHAT 250
    PEALFNPILM MALAALGIGS VSTLLVAMSI ADPLRQLRWA LSEVQRGNYN 300
    AHMQIYDASE LGLLQAGFND MVRELSERQR LRDLFGRYVG EDVARRALER 350
    GTELGGQERD VAVLFVDLVG STQLAATRPP AEVVQLLNEF FRVVVETVAR 400
    HGGFVNKFQG DAALAIFGAP IEHPDGAGAA LSAARELHDE LIPVLGSAEF 450
    GIGVSAGRAI AGHIGAQARF EYTVIGDPVN EAARLTELAK LEDGHVLASA 500
    IAVSGALDAE ALCWDVGEVV ELRGRAAPTQ LARPMNLAAP EEVSSEVRG 549
    Length:549
    Mass (Da):58,759
    Last modified:July 1, 1997 - v1
    Checksum:i28E642515868470B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000516 Genomic DNA. Translation: AAK48108.1.
    JLBH01000004 Genomic DNA. Translation: KBN09440.1.
    PIRiF70563.
    RefSeqiNP_338294.1. NC_002755.2.

    Genome annotation databases

    EnsemblBacteriaiAAK48108; AAK48108; MT3748.
    CCP46468; CCP46468; Rv3645.
    GeneIDi926496.
    KEGGimtc:MT3748.
    PATRICi18130000. VBIMycTub22151_4093.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000516 Genomic DNA. Translation: AAK48108.1 .
    JLBH01000004 Genomic DNA. Translation: KBN09440.1 .
    PIRi F70563.
    RefSeqi NP_338294.1. NC_002755.2.

    3D structure databases

    SMRi O06362. Positions 282-542.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 83332.Rv3645.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK48108 ; AAK48108 ; MT3748 .
    CCP46468 ; CCP46468 ; Rv3645 .
    GeneIDi 926496.
    KEGGi mtc:MT3748.
    PATRICi 18130000. VBIMycTub22151_4093.

    Organism-specific databases

    TubercuListi Rv3645.

    Phylogenomic databases

    HOGENOMi HOG000045754.
    KOi K01768.
    OMAi VHRNKGI.
    OrthoDBi EOG6HXJ1J.

    Enzyme and pathway databases

    BioCyci MTBRV:RV3645-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.1230. 1 hit.
    InterProi IPR001054. A/G_cyclase.
    IPR003660. HAMP_linker_domain.
    [Graphical view ]
    Pfami PF00211. Guanylate_cyc. 1 hit.
    PF00672. HAMP. 1 hit.
    [Graphical view ]
    SMARTi SM00044. CYCc. 1 hit.
    SM00304. HAMP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 1 hit.
    PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CDC 1551 / OshkoshImported and CDC1551Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CDC1551.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Cdc1551Imported.

    Entry informationi

    Entry nameiO06362_MYCTO
    AccessioniPrimary (citable) accession number: O06362
    Secondary accession number(s): F2GF18, Q7D553
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 1997
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3