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O06362

- O06362_MYCTO

UniProt

O06362 - O06362_MYCTO

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Protein
Submitted name:

Adenylate cyclase

Gene

MT3748

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: MTBBASE
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. ATP catabolic process Source: MTBBASE
  2. cAMP biosynthetic process Source: GOC
  3. cAMP catabolic process Source: MTBBASE
  4. intracellular signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciMTBRV:RV3645-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclaseImported
Submitted name:
Adenylate cyclase, putativeImported
Gene namesi
Ordered Locus Names:MT3748Imported
ORF Names:V735_03781Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001020: Chromosome

Organism-specific databases

TubercuListiRv3645.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3645.

Structurei

3D structure databases

ProteinModelPortaliO06362.
SMRiO06362. Positions 280-326, 357-528.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000045754.
InParanoidiO06362.
KOiK01768.
OMAiVHRNKGI.
OrthoDBiEOG6HXJ1J.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O06362-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDAEAFVGFR QVPAARYGGL MATTAALPRR IHAFVRWVVR TPWPLFSLSM
60 70 80 90 100
LQSDIIGALF VLGFLRYGLP PQDNIQLQDL PPVNLLIFVS TVIILFLAGA
110 120 130 140 150
VVNLKLLMPV FRWQRRDNLL TEPDPAATEL ARSRALRMPL YRTLISLAVW
160 170 180 190 200
ATGGGVFILA SWSVAKHAAP VVAVATALGA TATAIIGYLQ SERVLRPVAV
210 220 230 240 250
AALRSGVPEN VNAPGVILRL MLAWIPSTGV PLLAIVLAVA ADKIALLHAT
260 270 280 290 300
PEALFNPILM MALAALGIGS VSTLLVAMSI ADPLRQLRWA LSEVQRGNYN
310 320 330 340 350
AHMQIYDASE LGLLQAGFND MVRELSERQR LRDLFGRYVG EDVARRALER
360 370 380 390 400
GTELGGQERD VAVLFVDLVG STQLAATRPP AEVVQLLNEF FRVVVETVAR
410 420 430 440 450
HGGFVNKFQG DAALAIFGAP IEHPDGAGAA LSAARELHDE LIPVLGSAEF
460 470 480 490 500
GIGVSAGRAI AGHIGAQARF EYTVIGDPVN EAARLTELAK LEDGHVLASA
510 520 530 540
IAVSGALDAE ALCWDVGEVV ELRGRAAPTQ LARPMNLAAP EEVSSEVRG
Length:549
Mass (Da):58,759
Last modified:July 1, 1997 - v1
Checksum:i28E642515868470B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK48108.1.
JLBH01000004 Genomic DNA. Translation: KBN09440.1.
PIRiF70563.
RefSeqiNP_338294.1. NC_002755.2.

Genome annotation databases

EnsemblBacteriaiAAK48108; AAK48108; MT3748.
CCP46468; CCP46468; Rv3645.
GeneIDi926496.
KEGGimtc:MT3748.
PATRICi18130000. VBIMycTub22151_4093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK48108.1 .
JLBH01000004 Genomic DNA. Translation: KBN09440.1 .
PIRi F70563.
RefSeqi NP_338294.1. NC_002755.2.

3D structure databases

ProteinModelPortali O06362.
SMRi O06362. Positions 280-326, 357-528.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 83332.Rv3645.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK48108 ; AAK48108 ; MT3748 .
CCP46468 ; CCP46468 ; Rv3645 .
GeneIDi 926496.
KEGGi mtc:MT3748.
PATRICi 18130000. VBIMycTub22151_4093.

Organism-specific databases

TubercuListi Rv3645.

Phylogenomic databases

HOGENOMi HOG000045754.
InParanoidi O06362.
KOi K01768.
OMAi VHRNKGI.
OrthoDBi EOG6HXJ1J.

Enzyme and pathway databases

BioCyci MTBRV:RV3645-MONOMER.

Family and domain databases

Gene3Di 3.30.70.1230. 1 hit.
InterProi IPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view ]
SMARTi SM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 1 hit.
PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CDC 1551 / OshkoshImported and CDC1551Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CDC1551.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cdc1551Imported.

Entry informationi

Entry nameiO06362_MYCTO
AccessioniPrimary (citable) accession number: O06362
Secondary accession number(s): F2GF18, Q7D553
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 26, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3