O06327 (RS13_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S13

Gene names

Name:	rpsM
Ordered Locus Names:	Rv3460c, MT3567
ORF Names:	MTCY13E12.13c

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	124 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites By similarity. HAMAP MF_01315_B
Subunit structure	Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein S13P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from direct assay. Source: MTBBASE ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 124	124	30S ribosomal protein S13 HAMAP MF_01315_B		PRO_0000132114

Sequences

	Sequence		Length	Mass (Da)
	O06327 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 93B44CB17A4503B1	FASTA	124	14,351
	10 20 30 40 50 60 MARLVGVDLP RDKRMEVALT YIFGIGRTRS NEILAATGID RDLRTRDLTE EQLIHLRDYI 70 80 90 100 110 120 EANLKVEGDL RREVQADIRR KIEIGCYQGL RHRRGMPVRG QRTKTNARTR KGPKRTIAGK KKAR

References

[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842583 Genomic DNA. Translation: CAB08726.1. AE000516 Genomic DNA. Translation: AAK47906.1.
PIR	A70566.
RefSeq	NP_217977.1. NC_000962.2. NP_338092.1. NC_002755.2.
3D structure databases
ProteinModelPortal	O06327.
SMR	O06327. Positions 2-123.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000002449; EBMYCP00000002449; EBMYCG00000002447. EBMYCT00000070559; EBMYCP00000068618; EBMYCG00000070554.
GeneID	887514. 926626.
GenomeReviews	Gene locus MT3567 in contig AE000516_GR. Gene locus Rv3460c in contig AL123456_GR.
KEGG	mtc:MT3567. mtu:Rv3460c.
PATRIC	18129571. VBIMycTub22151_3881.
TIGR	MT3567.
Organism-specific databases
TubercuList	Rv3460c.
Phylogenomic databases
GeneTree	EBGT00050000015674.
HOGENOM	HBG737405.
OMA	YRGRRHR.
PhylomeDB	O06327.
ProtClustDB	PRK05179.
Family and domain databases
HAMAP	MF_01315_B. Ribosomal_S13_B. [Tree]
InterPro	IPR001892. Ribosomal_S13. IPR010979. Ribosomal_S13-like_H2TH. IPR019980. Ribosomal_S13_bac-type. IPR018269. Ribosomal_S13_CS. [Graphical view]
KO	K02952.
PANTHER	PTHR10871. PTHR10871. 1 hit.
Pfam	PF00416. Ribosomal_S13. 1 hit. [Graphical view]
PIRSF	PIRSF002134. Ribosomal_S13. 1 hit.
SUPFAM	SSF46946. Ribosomal_H2TH. 1 hit.
TIGRFAMs	TIGR03631. Bact_S13. 1 hit.
PROSITE	PS00646. RIBOSOMAL_S13_1. 1 hit. PS50159. RIBOSOMAL_S13_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS13_MYCTU

Accession

Primary (citable) accession number: O06327

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	July 1, 1997
Last modified:	January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program