Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O06249 (O06249_MYCTO) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=4.1.1.15 EMBL AAK47878.1

Glutamate decarboxylase GadB EMBL KBN10368.1
Gene names
Name:gadB EMBL AAK47878.1
Ordered Locus Names:MT3538 EMBL AAK47878.1
ORF Names:V735_03555 EMBL KBN10368.1
OrganismMycobacterium tuberculosis (strain CDC 1551 / Oshkosh) [Complete proteome] [HAMAP] EMBL AAK47878.1
Taxonomic identifier83331 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000382

Sequence similarities

Belongs to the group II decarboxylase family. RuleBase RU000382

Sequences

Sequence LengthMass (Da)Tools
O06249 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: B5DA3156D4C7CB4F

FASTA46050,780
        10         20         30         40         50         60 
MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM LDGSSRLNLA 

        70         80         90        100        110        120 
TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV SMVADLFHAE GLRDHDPTSA 

       130        140        150        160        170        180 
TGVSTIGSSE AVMLGGLALK WRWRQRVGSW KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY 

       190        200        210        220        230        240 
LPMERGRYVI TPEQVLAAVD ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP 

       250        260        270        280        290        300 
VHVDAASGGF VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 

       310        320        330        340        350        360 
VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT ARWLGDQLRE 

       370        380        390        400        410        420 
VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW QVPAYTMPDN ATDVAVLRIV 

       430        440        450        460 
VREGLSADLA RALHDDAVTA LAALDKVKPG GHFDAQHFAH 

« Hide

References

« Hide 'large scale' references
[1]"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains."
Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. expand/collapse author list , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R.Jr., Venter J.C., Fraser C.M.
J. Bacteriol. 184:5479-5490(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CDC 1551 / Oshkosh and CDC1551 EMBL AAK47878.1.
[2]Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R.T., Dodson R., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. expand/collapse author list , Weidman J., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R.Jr., Venter J.C., Fraser C.M.
Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CDC1551.
[3]"The Genome Sequence of Mycobacterium tuberculosis cdc1551."
The Broad Institute Genomics Platform, The Broad Institute Genome Sequencing Center for Infectious Disease
Earl A.M., Hung D., Gomez D., Hsueh P.R., Rozo J.C., Zambrano M.M., Desjardins C., Abeel T., Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S. expand/collapse author list , Hansen M., Howarth C., Imamovic A., Larimer J., Murphy C., Naylor J., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.
Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Cdc1551 EMBL KBN10368.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000516 Genomic DNA. Translation: AAK47878.1.
JLBH01000003 Genomic DNA. Translation: KBN10368.1.
PIRF70975.
RefSeqNP_338064.1. NC_002755.2.

3D structure databases

ProteinModelPortalO06249.
SMRO06249. Positions 12-447.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING83332.Rv3432c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK47878; AAK47878; MT3538.
CCP46254; CCP46254; Rv3432c.
GeneID922626.
KEGGmtc:MT3538.
mtu:Rv3432c.
mtv:RVBD_3432c.
PATRIC18129513. VBIMycTub22151_3852.

Organism-specific databases

TubercuListRv3432c.
CMRSearch...

Phylogenomic databases

HOGENOMHOG000070228.
KOK01580.
OMAPTFQINF.
OrthoDBEOG6TFCPW.

Enzyme and pathway databases

BioCycMTBRV:RV3432C-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
InterProIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameO06249_MYCTO
AccessionPrimary (citable) accession number: O06249
Secondary accession number(s): F2GI04, Q7D5J9
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: July 9, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)