O06049 (RL16_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L16

Gene names

Name:	rplP
Ordered Locus Names:	Mb0728

Organism

Mycobacterium bovis [Complete proteome] [HAMAP]

Taxonomic identifier

1765 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	138 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs By similarity. HAMAP MF_01342
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L16P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 138	138	50S ribosomal protein L16 HAMAP MF_01342		PRO_0000062135
Experimental info
	Sequence conflict	63	1	K → E in CAA73679. Ref.1
	Sequence conflict	71	1	D → G in CAA73679. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	O06049 [UniParc]. Last modified November 28, 2003. Version 2. Checksum: 2C878FC597C69D0C	FASTA	138	15,692
	10 20 30 40 50 60 MLIPRKVKHR KQHHPRQRGI ASGGTTVNFG DYGIQALEHA YVTNRQIESA RIAINRHIKR 70 80 90 100 110 120 GGKVWINIFP DRPLTKKPAE TRMGSGKGSP EWWVANVKPG RVLFELSYPN EGVARAALTR 130 AIHKLPIKAR IITREEQF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The role of ribosomal RNAs in macrolide resistance." Sander P., Prammananan T., Meier A., Frischkorn K., Boettger E.C. Mol. Microbiol. 26:469-480(1997) [PubMed: 9402018] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BCG.
[2]	"The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. , Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G. Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y13228 Genomic DNA. Translation: CAA73679.1. BX248336 Genomic DNA. Translation: CAD93590.1.
RefSeq	NP_854386.1. NC_002945.3.
3D structure databases
ProteinModelPortal	O06049.
SMR	O06049. Positions 1-134.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000016090; EBMYCP00000015925; EBMYCG00000016085.
GeneID	1091859.
GenomeReviews	Gene locus Mb0728 in contig BX248333_GR.
KEGG	mbo:Mb0728.
PATRIC	18003260. VBIMycBov88188_0794.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016297.
HOGENOM	HBG286097.
OMA	KGSPEFW.
ProtClustDB	PRK09203.
Enzyme and pathway databases
BioCyc	MBOV233413:MB0728-MONOMER.
Family and domain databases
HAMAP	MF_01342. Ribosomal_L16. [Tree]
InterPro	IPR016180. Ribosomal_L10e/L16. IPR000114. Ribosomal_L16. IPR020798. Ribosomal_L16_CS. [Graphical view]
KO	K02878.
Pfam	PF00252. Ribosomal_L16. 1 hit. [Graphical view]
PRINTS	PR00060. RIBOSOMALL16.
SUPFAM	SSF54686. Ribosomal_L10e/L16. 1 hit.
TIGRFAMs	TIGR01164. RplP_bact. 1 hit.
PROSITE	PS00586. RIBOSOMAL_L16_1. 1 hit. PS00701. RIBOSOMAL_L16_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL16_MYCBO

Accession

Primary (citable) accession number: O06049

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 28, 2003
Last modified:	January 25, 2012
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program