Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O05973

- UDG_RICPR

UniProt

O05973 - UDG_RICPR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UDP-glucose 6-dehydrogenase

Gene

udg

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei260 – 2601By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi2 – 1918NADSequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. UDP-glucose 6-dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. polysaccharide biosynthetic process Source: InterPro
  2. UDP-glucuronate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

UniPathwayiUPA00038; UER00491.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose 6-dehydrogenase (EC:1.1.1.22)
Short name:
UDP-Glc dehydrogenase
Short name:
UDP-GlcDH
Short name:
UDPGDH
Gene namesi
Name:udg
Ordered Locus Names:RP779
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434UDP-glucose 6-dehydrogenasePRO_0000074052Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP779.

Structurei

3D structure databases

ProteinModelPortaliO05973.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1004.
HOGENOMiHOG000153773.
KOiK00012.
OMAiRETNPTA.
OrthoDBiEOG6ZSP7N.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view]
PANTHERiPTHR11374. PTHR11374. 1 hit.
PfamiPF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTiSM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsiTIGR03026. NDP-sugDHase. 1 hit.

Sequencei

Sequence statusi: Complete.

O05973-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNITFIGSGY VGLVSGIIMG YLGHNVTCLD NDDVKISKLN KKILPIYEAK
60 70 80 90 100
LDEYLKHALE SDRLKFTNIY SNEFRNFDAI FITVGTPSKE LGEADLKYVY
110 120 130 140 150
DAVDKVSKHI NKDCLIVIKS TVPPGSCNNI IAYLKAKGFS FNVASNPEFL
160 170 180 190 200
REGSAVEDFL YPDRIVVGVN NKESEALLRK IYAPLIEQGA KFLVTNLVTS
210 220 230 240 250
ELIKYVSNSF LATKIAFINE MADLCEKIGA NIKDLSQGVG LDQRIGRNFL
260 270 280 290 300
NAGPGFGGSC FPKDILALNN LVENHKIDCK ILKSVIKSNK LRPSNMVAKI
310 320 330 340 350
ATLLDGDLKG RNIAILGLTY KAGTDDVRAS PAIEIITILL NKDVYVKAFD
360 370 380 390 400
PIGLENAKKN LEHKNLLYFA SAVEACKSVD IIVIATEWSE FKELNWQEIY
410 420 430
NLVKSPMIID LRNILDNEVM KKIGFRYYAV GSQI
Length:434
Mass (Da):48,226
Last modified:July 1, 1997 - v1
Checksum:i15991BA7112D5036
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11785 Genomic DNA. Translation: CAA72478.1.
AJ235273 Genomic DNA. Translation: CAA15205.1.
PIRiE71638.
RefSeqiNP_221129.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15205; CAA15205; CAA15205.
GeneIDi883765.
KEGGirpr:RP779.
PATRICi17902426. VBIRicPro72556_0815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11785 Genomic DNA. Translation: CAA72478.1 .
AJ235273 Genomic DNA. Translation: CAA15205.1 .
PIRi E71638.
RefSeqi NP_221129.1. NC_000963.1.

3D structure databases

ProteinModelPortali O05973.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272947.RP779.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA15205 ; CAA15205 ; CAA15205 .
GeneIDi 883765.
KEGGi rpr:RP779.
PATRICi 17902426. VBIRicPro72556_0815.

Phylogenomic databases

eggNOGi COG1004.
HOGENOMi HOG000153773.
KOi K00012.
OMAi RETNPTA.
OrthoDBi EOG6ZSP7N.

Enzyme and pathway databases

UniPathwayi UPA00038 ; UER00491 .

Family and domain databases

Gene3Di 3.40.50.720. 2 hits.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view ]
PANTHERi PTHR11374. PTHR11374. 1 hit.
Pfami PF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTi SM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsi TIGR03026. NDP-sugDHase. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
    Andersson J.O., Andersson S.G.E.
    Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Madrid E.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiUDG_RICPR
AccessioniPrimary (citable) accession number: O05973
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: October 1, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3