O05968 (SSRP_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	RP430

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP-Rule MF_00023
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00023.
Sequence similarities	Belongs to the SmpB family.
Caution	SsrA has yet not been found in R.prowazekii, so the function of this protein is not obvious.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	SsrA-binding protein HAMAP-Rule MF_00023		PRO_0000103018

Sequences

	Sequence		Length	Mass (Da)
	O05968 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 09C99FE05DDF3C1D	FASTA	152	17,770
	10 20 30 40 50 60 MIEDKKVIVQ NKKALFNYFI EEILEAGIVL KGSEVQSLRQ GKASIEESHA SDNGHEVFLY 70 80 90 100 110 120 NCHITEYEKA NRFNHSTRRP RKLLLHAKEI KKIIGRIRIK GYTLVALSMY FNKKNKVKVE 130 140 150 LGIAKGKKLY DKRAAIKEKD WKKDQSRLIR QK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence." Andersson J.O., Andersson S.G.E. Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Madrid E.
[2]	"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y11777 Genomic DNA. Translation: CAA72448.1. AJ235271 Genomic DNA. Translation: CAA14887.1.
PIR	E71701.
RefSeq	NP_220811.1. NC_000963.1.
3D structure databases
ProteinModelPortal	O05968.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP430.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA14887; CAA14887; CAA14887.
GeneID	883303.
KEGG	rpr:RP430.
PATRIC	17901641. VBIRicPro72556_0443.
Phylogenomic databases
eggNOG	COG0691.
HOGENOM	HOG000009628.
KO	K03664.
OMA	HVSALNS.
ProtClustDB	PRK05422.
Family and domain databases
Gene3D	2.40.280.10. 1 hit.
HAMAP	MF_00023. SmpB.
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. smpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_RICPR

Accession

Primary (citable) accession number: O05968

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 1, 1997
Last modified:	May 29, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program