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O05968

- SSRP_RICPR

UniProt

O05968 - SSRP_RICPR

Protein

SsrA-binding protein

Gene

smpB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes.UniRule annotation

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SsrA-binding proteinUniRule annotation
    Gene namesi
    Name:smpBUniRule annotation
    Ordered Locus Names:RP430
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 152152SsrA-binding proteinPRO_0000103018Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272947.RP430.

    Structurei

    3D structure databases

    ProteinModelPortaliO05968.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SmpB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0691.
    HOGENOMiHOG000009628.
    KOiK03664.
    OMAiPLKIYIK.
    OrthoDBiEOG6HXJ9P.

    Family and domain databases

    Gene3Di2.40.280.10. 1 hit.
    HAMAPiMF_00023. SmpB.
    InterProiIPR023620. SmpB.
    IPR000037. SsrA-bd_prot.
    IPR020081. SsrA-bd_prot_CS.
    [Graphical view]
    PfamiPF01668. SmpB. 1 hit.
    [Graphical view]
    ProDomiPD004488. SmpB. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF74982. SSF74982. 1 hit.
    TIGRFAMsiTIGR00086. smpB. 1 hit.
    PROSITEiPS01317. SSRP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O05968-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIEDKKVIVQ NKKALFNYFI EEILEAGIVL KGSEVQSLRQ GKASIEESHA    50
    SDNGHEVFLY NCHITEYEKA NRFNHSTRRP RKLLLHAKEI KKIIGRIRIK 100
    GYTLVALSMY FNKKNKVKVE LGIAKGKKLY DKRAAIKEKD WKKDQSRLIR 150
    QK 152
    Length:152
    Mass (Da):17,770
    Last modified:July 1, 1997 - v1
    Checksum:i09C99FE05DDF3C1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y11777 Genomic DNA. Translation: CAA72448.1.
    AJ235271 Genomic DNA. Translation: CAA14887.1.
    PIRiE71701.
    RefSeqiNP_220811.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA14887; CAA14887; CAA14887.
    GeneIDi883303.
    KEGGirpr:RP430.
    PATRICi17901641. VBIRicPro72556_0443.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y11777 Genomic DNA. Translation: CAA72448.1 .
    AJ235271 Genomic DNA. Translation: CAA14887.1 .
    PIRi E71701.
    RefSeqi NP_220811.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali O05968.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP430.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA14887 ; CAA14887 ; CAA14887 .
    GeneIDi 883303.
    KEGGi rpr:RP430.
    PATRICi 17901641. VBIRicPro72556_0443.

    Phylogenomic databases

    eggNOGi COG0691.
    HOGENOMi HOG000009628.
    KOi K03664.
    OMAi PLKIYIK.
    OrthoDBi EOG6HXJ9P.

    Family and domain databases

    Gene3Di 2.40.280.10. 1 hit.
    HAMAPi MF_00023. SmpB.
    InterProi IPR023620. SmpB.
    IPR000037. SsrA-bd_prot.
    IPR020081. SsrA-bd_prot_CS.
    [Graphical view ]
    Pfami PF01668. SmpB. 1 hit.
    [Graphical view ]
    ProDomi PD004488. SmpB. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF74982. SSF74982. 1 hit.
    TIGRFAMsi TIGR00086. smpB. 1 hit.
    PROSITEi PS01317. SSRP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
      Andersson J.O., Andersson S.G.E.
      Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Madrid E.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiSSRP_RICPR
    AccessioniPrimary (citable) accession number: O05968
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    SsrA has yet not been found in R.prowazekii, so the function of this protein is not obvious.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3