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Protein

SsrA-binding protein

Gene

smpB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes.UniRule annotation

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
SsrA-binding proteinUniRule annotation
Gene namesi
Name:smpBUniRule annotation
Ordered Locus Names:RP430
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 152152SsrA-binding proteinPRO_0000103018Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP430.

Structurei

3D structure databases

ProteinModelPortaliO05968.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SmpB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0691.
HOGENOMiHOG000009628.
KOiK03664.
OMAiNHAPRRK.
OrthoDBiEOG6HXJ9P.

Family and domain databases

Gene3Di2.40.280.10. 1 hit.
HAMAPiMF_00023. SmpB.
InterProiIPR023620. SmpB.
IPR000037. SsrA-bd_prot.
IPR020081. SsrA-bd_prot_CS.
[Graphical view]
PfamiPF01668. SmpB. 1 hit.
[Graphical view]
ProDomiPD004488. SmpB. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF74982. SSF74982. 1 hit.
TIGRFAMsiTIGR00086. smpB. 1 hit.
PROSITEiPS01317. SSRP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O05968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEDKKVIVQ NKKALFNYFI EEILEAGIVL KGSEVQSLRQ GKASIEESHA
60 70 80 90 100
SDNGHEVFLY NCHITEYEKA NRFNHSTRRP RKLLLHAKEI KKIIGRIRIK
110 120 130 140 150
GYTLVALSMY FNKKNKVKVE LGIAKGKKLY DKRAAIKEKD WKKDQSRLIR

QK
Length:152
Mass (Da):17,770
Last modified:July 1, 1997 - v1
Checksum:i09C99FE05DDF3C1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11777 Genomic DNA. Translation: CAA72448.1.
AJ235271 Genomic DNA. Translation: CAA14887.1.
PIRiE71701.
RefSeqiNP_220811.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14887; CAA14887; CAA14887.
GeneIDi883303.
KEGGirpr:RP430.
PATRICi17901641. VBIRicPro72556_0443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11777 Genomic DNA. Translation: CAA72448.1.
AJ235271 Genomic DNA. Translation: CAA14887.1.
PIRiE71701.
RefSeqiNP_220811.1. NC_000963.1.

3D structure databases

ProteinModelPortaliO05968.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP430.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA14887; CAA14887; CAA14887.
GeneIDi883303.
KEGGirpr:RP430.
PATRICi17901641. VBIRicPro72556_0443.

Phylogenomic databases

eggNOGiCOG0691.
HOGENOMiHOG000009628.
KOiK03664.
OMAiNHAPRRK.
OrthoDBiEOG6HXJ9P.

Family and domain databases

Gene3Di2.40.280.10. 1 hit.
HAMAPiMF_00023. SmpB.
InterProiIPR023620. SmpB.
IPR000037. SsrA-bd_prot.
IPR020081. SsrA-bd_prot_CS.
[Graphical view]
PfamiPF01668. SmpB. 1 hit.
[Graphical view]
ProDomiPD004488. SmpB. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF74982. SSF74982. 1 hit.
TIGRFAMsiTIGR00086. smpB. 1 hit.
PROSITEiPS01317. SSRP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
    Andersson J.O., Andersson S.G.E.
    Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Madrid E.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiSSRP_RICPR
AccessioniPrimary (citable) accession number: O05968
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: February 4, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

SsrA has yet not been found in R.prowazekii, so the function of this protein is not obvious.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.