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O05968 (SSRP_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SsrA-binding protein
Gene names
Name:smpB
Ordered Locus Names:RP430
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length152 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP-Rule MF_00023

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00023.

Sequence similarities

Belongs to the SmpB family.

Caution

SsrA has yet not been found in R.prowazekii, so the function of this protein is not obvious.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandRNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 152152SsrA-binding protein HAMAP-Rule MF_00023
PRO_0000103018

Sequences

Sequence LengthMass (Da)Tools
O05968 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 09C99FE05DDF3C1D

FASTA15217,770
        10         20         30         40         50         60 
MIEDKKVIVQ NKKALFNYFI EEILEAGIVL KGSEVQSLRQ GKASIEESHA SDNGHEVFLY 

        70         80         90        100        110        120 
NCHITEYEKA NRFNHSTRRP RKLLLHAKEI KKIIGRIRIK GYTLVALSMY FNKKNKVKVE 

       130        140        150 
LGIAKGKKLY DKRAAIKEKD WKKDQSRLIR QK 

« Hide

References

« Hide 'large scale' references
[1]"Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
Andersson J.O., Andersson S.G.E.
Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Madrid E.
[2]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y11777 Genomic DNA. Translation: CAA72448.1.
AJ235271 Genomic DNA. Translation: CAA14887.1.
PIRE71701.
RefSeqNP_220811.1. NC_000963.1.

3D structure databases

ProteinModelPortalO05968.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA14887; CAA14887; CAA14887.
GeneID883303.
KEGGrpr:RP430.
PATRIC17901641. VBIRicPro72556_0443.

Phylogenomic databases

eggNOGCOG0691.
HOGENOMHOG000009628.
KOK03664.
OMARDWQREK.
OrthoDBEOG6HXJ9P.
ProtClustDBPRK05422.

Family and domain databases

Gene3D2.40.280.10. 1 hit.
HAMAPMF_00023. SmpB.
InterProIPR023620. SmpB.
IPR000037. SsrA-bd_prot.
IPR020081. SsrA-bd_prot_CS.
[Graphical view]
PfamPF01668. SmpB. 1 hit.
[Graphical view]
ProDomPD004488. SmpB. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF74982. SSF74982. 1 hit.
TIGRFAMsTIGR00086. smpB. 1 hit.
PROSITEPS01317. SSRP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSSRP_RICPR
AccessionPrimary (citable) accession number: O05968
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names