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O05962

- TLCE_RICPR

UniProt

O05962 - TLCE_RICPR

Protein

ADP,ATP carrier protein 5

Gene

tlcE

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (30 May 2000)
      Previous versions | rss
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    Functioni

    Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.By similarity

    GO - Molecular functioni

    1. ATP:ADP antiporter activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. nucleobase-containing compound transport Source: CACAO

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Protein family/group databases

    TCDBi2.A.12.1.5. the atp:adp antiporter (aaa) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ADP,ATP carrier protein 5
    Alternative name(s):
    ADP/ATP translocase 5
    Gene namesi
    Name:tlcE
    Synonyms:tlc5
    Ordered Locus Names:RP739
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 500500ADP,ATP carrier protein 5PRO_0000102584Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO05962.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei26 – 4621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei62 – 8221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei94 – 11421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei149 – 16921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei184 – 20421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei224 – 24421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei287 – 30721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei328 – 34821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei357 – 37721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei381 – 40121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei469 – 48921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADP/ATP translocase tlc family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3202.
    HOGENOMiHOG000238123.
    KOiK03301.
    OMAiMQHEREA.
    OrthoDBiEOG6BCSND.

    Family and domain databases

    InterProiIPR004667. ADP_ATP_car.
    [Graphical view]
    PfamiPF03219. TLC. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00769. AAA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O05962-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSTSPSRSF KNKFRAAFWP VHNYELGKFI PISALMFCIL FNQNILRILK    50
    DSILISEISA EIAGFAKVYC VTPVAALFVI IYAKMINHLT FEKIFYYLSA 100
    FFISCFILFA FVIYPNIHIF HVHPDTLSDW MNKYPHFKWY ISLVGNWGYI 150
    VYYSLAELWP NIFYVLLFWQ FTNELTTTEE AKRFYTLFSL FGNSSLILVG 200
    FLMMNLSSED TIIKKFISIS DSKITLVQVS TTIIAIVAII CCLLVRFISK 250
    YIFTNPLFYH KTKSSRSTAQ RMGLIKSFKY IVKSKYLWLL LICSAAFGFA 300
    INLVEAVWKA KIKELYPTVN TYAEFNSLYI LWTGVAIIVM TIIGNNVMRM 350
    HNWFVAAVIS PVIIMVTGVL FFGLIVFDQQ ILSLFDGAIL MSPLALAVSI 400
    GGIQNILAKG TKYSIWDTSR EMLYIPLDDE LKTKGKAAVD VISAKVGKSS 450
    SGLVQSIIFT LVPNATFTSI SPILMVVFTF VCFAWIYAVR KIYFEYQKIA 500
    Length:500
    Mass (Da):57,074
    Last modified:May 30, 2000 - v2
    Checksum:iFE3DB48D08CF5F72
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235273 Genomic DNA. Translation: CAA15167.1.
    Y11778 Genomic DNA. Translation: CAA72457.1.
    PIRiG71633.
    RefSeqiNP_221091.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA15167; CAA15167; CAA15167.
    GeneIDi883700.
    KEGGirpr:RP739.
    PATRICi17902337. VBIRicPro72556_0772.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235273 Genomic DNA. Translation: CAA15167.1 .
    Y11778 Genomic DNA. Translation: CAA72457.1 .
    PIRi G71633.
    RefSeqi NP_221091.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali O05962.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 2.A.12.1.5. the atp:adp antiporter (aaa) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA15167 ; CAA15167 ; CAA15167 .
    GeneIDi 883700.
    KEGGi rpr:RP739.
    PATRICi 17902337. VBIRicPro72556_0772.

    Phylogenomic databases

    eggNOGi COG3202.
    HOGENOMi HOG000238123.
    KOi K03301.
    OMAi MQHEREA.
    OrthoDBi EOG6BCSND.

    Family and domain databases

    InterProi IPR004667. ADP_ATP_car.
    [Graphical view ]
    Pfami PF03219. TLC. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00769. AAA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.
    2. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
      Andersson J.O., Andersson S.G.E.
      Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 325-500.
      Strain: Madrid E.

    Entry informationi

    Entry nameiTLCE_RICPR
    AccessioniPrimary (citable) accession number: O05962
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: May 30, 2000
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3