Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O05962

- TLCE_RICPR

UniProt

O05962 - TLCE_RICPR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

ADP,ATP carrier protein 5

Gene

tlcE

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).By similarity

GO - Molecular functioni

  1. ATP:ADP antiporter activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. nucleobase-containing compound transport Source: CACAO
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi2.A.12.1.5. the atp:adp antiporter (aaa) family.

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 5
Alternative name(s):
ADP/ATP translocase 5
Gene namesi
Name:tlcE
Synonyms:tlc5
Ordered Locus Names:RP739
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621HelicalSequence AnalysisAdd
BLAST
Transmembranei62 – 8221HelicalSequence AnalysisAdd
BLAST
Transmembranei94 – 11421HelicalSequence AnalysisAdd
BLAST
Transmembranei149 – 16921HelicalSequence AnalysisAdd
BLAST
Transmembranei184 – 20421HelicalSequence AnalysisAdd
BLAST
Transmembranei224 – 24421HelicalSequence AnalysisAdd
BLAST
Transmembranei287 – 30721HelicalSequence AnalysisAdd
BLAST
Transmembranei328 – 34821HelicalSequence AnalysisAdd
BLAST
Transmembranei357 – 37721HelicalSequence AnalysisAdd
BLAST
Transmembranei381 – 40121HelicalSequence AnalysisAdd
BLAST
Transmembranei469 – 48921HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500ADP,ATP carrier protein 5PRO_0000102584Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO05962.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ADP/ATP translocase tlc family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3202.
HOGENOMiHOG000238123.
KOiK03301.
OMAiMQHEREA.
OrthoDBiEOG6BCSND.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
[Graphical view]
PfamiPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

O05962-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSTSPSRSF KNKFRAAFWP VHNYELGKFI PISALMFCIL FNQNILRILK
60 70 80 90 100
DSILISEISA EIAGFAKVYC VTPVAALFVI IYAKMINHLT FEKIFYYLSA
110 120 130 140 150
FFISCFILFA FVIYPNIHIF HVHPDTLSDW MNKYPHFKWY ISLVGNWGYI
160 170 180 190 200
VYYSLAELWP NIFYVLLFWQ FTNELTTTEE AKRFYTLFSL FGNSSLILVG
210 220 230 240 250
FLMMNLSSED TIIKKFISIS DSKITLVQVS TTIIAIVAII CCLLVRFISK
260 270 280 290 300
YIFTNPLFYH KTKSSRSTAQ RMGLIKSFKY IVKSKYLWLL LICSAAFGFA
310 320 330 340 350
INLVEAVWKA KIKELYPTVN TYAEFNSLYI LWTGVAIIVM TIIGNNVMRM
360 370 380 390 400
HNWFVAAVIS PVIIMVTGVL FFGLIVFDQQ ILSLFDGAIL MSPLALAVSI
410 420 430 440 450
GGIQNILAKG TKYSIWDTSR EMLYIPLDDE LKTKGKAAVD VISAKVGKSS
460 470 480 490 500
SGLVQSIIFT LVPNATFTSI SPILMVVFTF VCFAWIYAVR KIYFEYQKIA
Length:500
Mass (Da):57,074
Last modified:May 30, 2000 - v2
Checksum:iFE3DB48D08CF5F72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235273 Genomic DNA. Translation: CAA15167.1.
Y11778 Genomic DNA. Translation: CAA72457.1.
PIRiG71633.
RefSeqiNP_221091.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15167; CAA15167; CAA15167.
GeneIDi883700.
KEGGirpr:RP739.
PATRICi17902337. VBIRicPro72556_0772.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235273 Genomic DNA. Translation: CAA15167.1 .
Y11778 Genomic DNA. Translation: CAA72457.1 .
PIRi G71633.
RefSeqi NP_221091.1. NC_000963.1.

3D structure databases

ProteinModelPortali O05962.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 2.A.12.1.5. the atp:adp antiporter (aaa) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA15167 ; CAA15167 ; CAA15167 .
GeneIDi 883700.
KEGGi rpr:RP739.
PATRICi 17902337. VBIRicPro72556_0772.

Phylogenomic databases

eggNOGi COG3202.
HOGENOMi HOG000238123.
KOi K03301.
OMAi MQHEREA.
OrthoDBi EOG6BCSND.

Family and domain databases

InterProi IPR004667. ADP_ATP_car.
[Graphical view ]
Pfami PF03219. TLC. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00769. AAA. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.
  2. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
    Andersson J.O., Andersson S.G.E.
    Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 325-500.
    Strain: Madrid E.

Entry informationi

Entry nameiTLCE_RICPR
AccessioniPrimary (citable) accession number: O05962
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: October 29, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3