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Protein

Uncharacterized hydrolase RP744

Gene

RP744

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei114 – 1141Charge relay systemBy similarity
Active sitei162 – 1621Charge relay systemBy similarity
Active sitei194 – 1941Charge relay systemBy similarity

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized hydrolase RP744 (EC:3.1.-.-)
Gene namesi
Ordered Locus Names:RP744
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215Uncharacterized hydrolase RP744PRO_0000102278Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP744.

Structurei

3D structure databases

ProteinModelPortaliO05958.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0400.
HOGENOMiHOG000260139.
KOiK06999.
OMAiDCHFISP.
OrthoDBiEOG6ZH2H7.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR003140. PLipase/COase/thioEstase.
[Graphical view]
PfamiPF02230. Abhydrolase_2. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

O05958-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKYLEYPEV ESKELPPQKL VVLLHGVGSD GHDLIGLVPY IKNDLPNCHF
60 70 80 90 100
ISPHGIEDYD MMPYGRQWFS LRDRSPHIIA KLIANNISKL EDIIREKQTE
110 120 130 140 150
LNLTNKDTVI IGFSQGTIIG LYLTLIQQKP LFCTIGFSGA LIPPMKVNNK
160 170 180 190 200
LTPICLIHGE LDQVINVSEM YNASNYLSKL NIEHSGHKLT SLAHSIDGRG
210
LEIAINFINT CHNIV
Length:215
Mass (Da):24,155
Last modified:July 1, 1997 - v1
Checksum:iD4683FF790849A96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11778 Genomic DNA. Translation: CAA72452.1.
AJ235273 Genomic DNA. Translation: CAA15172.1.
PIRiD71634.
RefSeqiNP_221096.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15172; CAA15172; CAA15172.
GeneIDi883994.
KEGGirpr:RP744.
PATRICi17902347. VBIRicPro72556_0777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11778 Genomic DNA. Translation: CAA72452.1.
AJ235273 Genomic DNA. Translation: CAA15172.1.
PIRiD71634.
RefSeqiNP_221096.1. NC_000963.1.

3D structure databases

ProteinModelPortaliO05958.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP744.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA15172; CAA15172; CAA15172.
GeneIDi883994.
KEGGirpr:RP744.
PATRICi17902347. VBIRicPro72556_0777.

Phylogenomic databases

eggNOGiCOG0400.
HOGENOMiHOG000260139.
KOiK06999.
OMAiDCHFISP.
OrthoDBiEOG6ZH2H7.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR003140. PLipase/COase/thioEstase.
[Graphical view]
PfamiPF02230. Abhydrolase_2. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic rearrangements during evolution of the obligate intracellular parasite Rickettsia prowazekii as inferred from an analysis of 52015 bp nucleotide sequence."
    Andersson J.O., Andersson S.G.E.
    Microbiology 143:2783-2795(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Madrid E.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiY744_RICPR
AccessioniPrimary (citable) accession number: O05958
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: January 7, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.