O05594 (O05594_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable resuscitation-promoting factor rpfB EMBL CAB08136.1

Gene names

Name:	rpfB EMBL CAB08136.1
Ordered Locus Names:	MT1038, Rv1009

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1XSF PDB 3EO5 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dormancy exit of symbiont in host Inferred from mutant phenotype. Source: MTBBASE negative regulation of gene expression Inferred from direct assay. Source: MTBBASE positive regulation of gene expression Inferred from direct assay. Source: MTBBASE positive regulation of growth rate Inferred from direct assay. Source: MTBBASE
Cellular component	extracellular region Inferred from direct assay. Source: MTBBASE
Molecular function	hydrolase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: MTBBASE
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O05594 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 02B55D8C70373D10	FASTA	362	38,078
	10 20 30 40 50 60 MLRLVVGALL LVLAFAGGYA VAACKTVTLT VDGTAMRVTT MKSRVIDIVE ENGFSVDDRD 70 80 90 100 110 120 DLYPAAGVQV HDADTIVLRR SRPLQISLDG HDAKQVWTTA STVDEALAQL AMTDTAPAAA 130 140 150 160 170 180 SRASRVPLSG MALPVVSAKT VQLNDGGLVR TVHLPAPNVA GLLSAAGVPL LQSDHVVPAA 190 200 210 220 230 240 TAPIVEGMQI QVTRNRIKKV TERLPLPPNA RRVEDPEMNM SREVVEDPGV PGTQDVTFAV 250 260 270 280 290 300 AEVNGVETGR LPVANVVVTP AHEAVVRVGT KPGTEVPPVI DGSIWDAIAG CEAGGNWAIN 310 320 330 340 350 360 TGNGYYGGVQ FDQGTWEANG GLRYAPRADL ATREEQIAVA EVTRLRQGWG AWPVCAARAG AR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
[3]	"The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes." Cohen-Gonsaud M., Barthe P., Bagneris C., Henderson B., Ward J., Roumestand C., Keep N.H. Nat. Struct. Mol. Biol. 12:270-273(2005) [PubMed: 15723078] [Abstract] Cited for: STRUCTURE BY NMR OF 255-362.
[4]	"Crystal structure of the resuscitation-promoting factor (DeltaDUF)RpfB from M. tuberculosis." Ruggiero A., Tizzano B., Pedone E., Pedone C., Wilmanns M., Berisio R. J. Mol. Biol. 385:153-162(2009) [PubMed: 18992255] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.83 ANGSTROMS) OF 194-362.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000516 Genomic DNA. Translation: AAK45288.1.
BX842575 Genomic DNA. Translation: CAB08136.1.

PIR

D70603.

RefSeq

NP_215525.1. NC_000962.2.
NP_335474.1. NC_002755.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1XSF	NMR	-	A	255-362	[»]
3EO5	X-ray	1.83	A	194-362	[»]

ProteinModelPortal

O05594.

SMR

O05594. Positions 255-362.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBMYCT00000003494; EBMYCP00000003494; EBMYCG00000003492.
EBMYCT00000072827; EBMYCP00000070886; EBMYCG00000072822.

GeneID

886048.
925164.

GenomeReviews

Gene locus MT1038 in contig AE000516_GR.
Gene locus Rv1009 in contig AL123456_GR.

KEGG

mtc:MT1038.
mtu:Rv1009.

PATRIC

18124026. VBIMycTub22151_1135.

TIGR

MT1038.

Organism-specific databases

TubercuList

Rv1009.

Phylogenomic databases

GeneTree

EBGT00050000014859.

HOGENOM

HBG292401.

OMA

WERQGGL.

ProtClustDB

CLSK790891.

Family and domain databases

InterPro

IPR007137. DUF348.
IPR011098. G5.
IPR010618. Transglycosylas.
[Graphical view]

Pfam

PF03990. DUF348. 3 hits.
PF07501. G5. 1 hit.
PF06737. Transglycosylas. 1 hit.
[Graphical view]

PROSITE

PS51109. G5. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O05594_MYCTU

Accession

Primary (citable) accession number: O05594
Secondary accession number(s): Q7D900

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)