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Protein

Sec-independent protein translocase protein TatCy

Gene

tatC2

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for YwbN secretion.UniRule annotation1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU05990-MONOMER.

Protein family/group databases

TCDBi2.A.64.3.2. the twin arginine targeting (tat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCyUniRule annotation
Gene namesi
Name:tatC2UniRule annotation
Synonyms:tatCy, ydiJ
Ordered Locus Names:BSU05990
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalUniRule annotationAdd BLAST21
Transmembranei67 – 87HelicalUniRule annotationAdd BLAST21
Transmembranei112 – 132HelicalUniRule annotationAdd BLAST21
Transmembranei157 – 177HelicalUniRule annotationAdd BLAST21
Transmembranei187 – 207HelicalUniRule annotationAdd BLAST21
Transmembranei212 – 232HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000980961 – 254Sec-independent protein translocase protein TatCyAdd BLAST254

Proteomic databases

PaxDbiO05523.

Interactioni

Subunit structurei

Forms a complex with TatAy. Two types of complexes exist: one composed of TatAy and TatCy, and another composed only of TatAy.

Protein-protein interaction databases

IntActiO05523. 22 interactors.
STRINGi224308.Bsubs1_010100003353.

Structurei

3D structure databases

ProteinModelPortaliO05523.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
InParanoidiO05523.
KOiK03118.
OMAiFPFVVDF.
PhylomeDBiO05523.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O05523-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRMKVNQMS LLEHIAELRK RLLIVALAFV VFFIAGFFLA KPIIVYLQET
60 70 80 90 100
DEAKQLTLNA FNLTDPLYVF MQFAFIIGIV LTSPVILYQL WAFVSPGLYE
110 120 130 140 150
KERKVTLSYI PVSILLFLAG LSFSYYILFP FVVDFMKRIS QDLNVNQVIG
160 170 180 190 200
INEYFHFLLQ LTIPFGLLFQ MPVILMFLTR LGIVTPMFLA KIRKYAYFTL
210 220 230 240 250
LVIAALITPP ELLSHMMVTV PLLILYEISI LISKAAYRKA QKSSAADRDV

SSGQ
Length:254
Mass (Da):29,056
Last modified:July 1, 1997 - v1
Checksum:i803DC23BCB6B24A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88802 Genomic DNA. Translation: BAA19723.1.
AL009126 Genomic DNA. Translation: CAB12418.1.
PIRiC69787.
RefSeqiNP_388480.1. NC_000964.3.
WP_010886426.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB12418; CAB12418; BSU05990.
GeneIDi938010.
KEGGibsu:BSU05990.
PATRICi18972830. VBIBacSub10457_0629.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88802 Genomic DNA. Translation: BAA19723.1.
AL009126 Genomic DNA. Translation: CAB12418.1.
PIRiC69787.
RefSeqiNP_388480.1. NC_000964.3.
WP_010886426.1. NC_000964.3.

3D structure databases

ProteinModelPortaliO05523.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO05523. 22 interactors.
STRINGi224308.Bsubs1_010100003353.

Protein family/group databases

TCDBi2.A.64.3.2. the twin arginine targeting (tat) family.

Proteomic databases

PaxDbiO05523.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12418; CAB12418; BSU05990.
GeneIDi938010.
KEGGibsu:BSU05990.
PATRICi18972830. VBIBacSub10457_0629.

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
InParanoidiO05523.
KOiK03118.
OMAiFPFVVDF.
PhylomeDBiO05523.

Enzyme and pathway databases

BioCyciBSUB:BSU05990-MONOMER.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTATCY_BACSU
AccessioniPrimary (citable) accession number: O05523
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

B.subtilis possesses two minimal, substrate-specific, Tat translocases: TatAd-TatCd and TatAy-TatCy, each one composed of a TatA and a TatC protein. TatA is bifunctional and performs the function of both the TatA and TatB proteins of Gram-negative organisms.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.