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Protein

Sec-independent protein translocase protein TatAy

Gene

tatAy

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion.UniRule annotation1 Publication

Miscellaneous

B.subtilis possesses two minimal, substrate-specific, Tat translocases: TatAd-TatCd and TatAy-TatCy, each one composed of a TatA and a TatC protein. TatA is bifunctional and performs the function of both the TatA and TatB proteins of Gram-negative organisms.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU05980-MONOMER.

Protein family/group databases

TCDBi2.A.64.3.2. the twin arginine targeting (tat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatAyUniRule annotation
Gene namesi
Name:tatAyUniRule annotation
Synonyms:ydiI
Ordered Locus Names:BSU05980
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000979801 – 57Sec-independent protein translocase protein TatAyAdd BLAST57

Proteomic databases

PaxDbiO05522.

Interactioni

Subunit structurei

Forms a complex with TatCy. Two types of complexes exist: one composed of TatAy and TatCy, and another composed only of TatAy. Cytosolic TatA forms large complexes or aggregates.UniRule annotation1 Publication

Protein-protein interaction databases

IntActiO05522. 16 interactors.
STRINGi224308.Bsubs1_010100003348.

Structurei

3D structure databases

ProteinModelPortaliO05522.
SMRiO05522.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatA/E family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41067S4. Bacteria.
ENOG410XUF0. LUCA.
HOGENOMiHOG000245365.
InParanoidiO05522.
KOiK03116.
OMAiFREFKNG.
PhylomeDBiO05522.

Family and domain databases

HAMAPiMF_00236. TatA_E. 1 hit.
InterProiView protein in InterPro
IPR003369. TatA/B/E.
IPR006312. TatA/E.
PfamiView protein in Pfam
PF02416. MttA_Hcf106. 1 hit.
TIGRFAMsiTIGR01411. tatAE. 1 hit.

Sequencei

Sequence statusi: Complete.

O05522-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIGPGSLAV IAIVALIIFG PKKLPELGKA AGDTLREFKN ATKGLTSDEE

EKKKEDQ
Length:57
Mass (Da):6,065
Last modified:July 1, 1997 - v1
Checksum:i91E4CB4138D8E751
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88802 Genomic DNA. Translation: BAA19722.1.
AL009126 Genomic DNA. Translation: CAB12417.1.
PIRiB69787.
RefSeqiNP_388479.1. NC_000964.3.
WP_003234072.1. NZ_JNCM01000032.1.

Genome annotation databases

EnsemblBacteriaiCAB12417; CAB12417; BSU05980.
GeneIDi939878.
KEGGibsu:BSU05980.
PATRICifig|224308.179.peg.643.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTATAY_BACSU
AccessioniPrimary (citable) accession number: O05522
Secondary accession number(s): Q797D3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: July 1, 1997
Last modified: June 7, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families