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O05518 (GCP_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp
Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein
Gene names
Name:gcp
Synonyms:ydiE
Ordered Locus Names:BSU05940
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445

Subcellular location

Cytoplasm Potential HAMAP MF_01445.

Sequence similarities

Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processproteolysis

Inferred from electronic annotation. Source: InterPro

tRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetalloendopeptidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 346346Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445
PRO_0000096957

Sequences

Sequence LengthMass (Da)Tools
O05518 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 0C7F1618780DBA1A

FASTA34636,842
        10         20         30         40         50         60 
MSEQKDMYVL GIETSCDETA AAIVKNGKEI ISNVVASQIE SHKRFGGVVP EIASRHHVEQ 

        70         80         90        100        110        120 
ITLVIEEAFR KAGMTYSDID AIAVTEGPGL VGALLIGVNA AKALSFAYNI PLVGVHHIAG 

       130        140        150        160        170        180 
HIYANRLVED IVFPALALVV SGGHTELVYM KEHGSFEVIG ETLDDAAGEA YDKVARTMGL 

       190        200        210        220        230        240 
PYPGGPQIDK LAEKGNDNIP LPRAWLEEGS YNFSFSGLKS AVINTLHNAS QKGQEIAPED 

       250        260        270        280        290        300 
LSASFQNSVI DVLVTKTARA AKEYDVKQVL LAGGVAANRG LRAALEKEFA QHEGITLVIP 

       310        320        330        340 
PLALCTDNAA MIAAAGTIAF EKGIRGAYDM NGQPGLELTS YQSLTR

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence and analysis of the phoB-rrnE-groESL region of the Bacillus subtilis chromosome."
Sadaie Y., Yata K., Fujita M., Sagai H., Itaya M., Kasahara Y., Ogasawara N.
Microbiology 143:1861-1866(1997) [PubMed: 9202461] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / JH642.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[3]"A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification."
El Yacoubi B., Hatin I., Deutsch C., Kahveci T., Rousset J.P., Iwata-Reuyl D., Murzin A.G., de Crecy-Lagard V.
EMBO J. 30:882-893(2011) [PubMed: 21285948] [Abstract]
Cited for: INTERACTION WITH YDIC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D88802 Genomic DNA. Translation: BAA19718.1.
AL009126 Genomic DNA. Translation: CAB12413.1.
PIRF69786.
RefSeqNP_388475.1. NC_000964.3.

3D structure databases

ProteinModelPortalO05518.
SMRO05518. Positions 7-342.
ModBaseSearch...

Protein family/group databases

MEROPSM22.A01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000000246; EBBACP00000000246; EBBACG00000000246.
GeneID938020.
GenomeReviewsGene locus BSU05940 in contig AL009126_GR.
KEGGbsu:BSU05940.
NMPDRfig|224308.1.peg.594.
PATRIC18972820. VBIBacSub10457_0624.

Organism-specific databases

GenoListBSU05940. [Micado]

Phylogenomic databases

GeneTreeEBGT00050000002496.
HOGENOMHBG304663.
OMAPAVGVHH.
PhylomeDBO05518.
ProtClustDBPRK09604.

Enzyme and pathway databases

BioCycBSUB:BSU05940-MONOMER.

Family and domain databases

HAMAPMF_01445. gcp.
[Tree]
InterProIPR022450. Pept_M22_O-sialoglycopept.
IPR000905. Peptidase_M22.
IPR017860. Peptidase_M22_CS.
IPR017861. Peptidase_M22_subgr.
[Graphical view]
KOK01409.
PfamPF00814. Peptidase_M22. 1 hit.
[Graphical view]
PRINTSPR00789. OSIALOPTASE.
TIGRFAMsTIGR03723. Bact_gcp. 1 hit.
TIGR00329. Gcp_kae1. 1 hit.
PROSITEPS01016. GLYCOPROTEASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCP_BACSU
AccessionPrimary (citable) accession number: O05518
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: January 25, 2012
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents