Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional regulator GmuR

Gene

gmuR

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi29 – 48H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU05850-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator GmuR
Alternative name(s):
Glucomannan utilization operon repressor
Glucomannan utilization protein R
Gene namesi
Name:gmuR
Synonyms:ydhQ
Ordered Locus Names:BSU05850
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003607271 – 237HTH-type transcriptional regulator GmuRAdd BLAST237

Proteomic databases

PaxDbiO05509.

Expressioni

Inductioni

Up-regulated by konjac glucomannan and by cellobiose and mannobiose, the possible degradation products of glucomannan. Repressed by glucose via the carbon catabolite repression system.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003278.

Structurei

3D structure databases

ProteinModelPortaliO05509.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 69HTH gntR-typePROSITE-ProRule annotationAdd BLAST69

Sequence similaritiesi

Contains 1 HTH gntR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108TZY. Bacteria.
COG2188. LUCA.
HOGENOMiHOG000228720.
InParanoidiO05509.
KOiK03492.
OMAiPVYYVVR.
PhylomeDBiO05509.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.40.1410.10. 1 hit.
InterProiIPR028978. Chorismate_lyase_/UTRA_dom.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011663. UTRA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00392. GntR. 1 hit.
PF07702. UTRA. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00345. HTH_GNTR. 1 hit.
SM00866. UTRA. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF64288. SSF64288. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O05509-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKYEIIANE MRNRIKNNVY PIDQPIPDEV SLAKEFNSSR MTMKRALDNL
60 70 80 90 100
VAEGLLFRKR GHGTFIIQSA IQDDHVHVVS NEILGLTNLL KDKKIKSKVI
110 120 130 140 150
QFEVQFPTEE VAAHLSIDQK TPVYYVVRLR IVEGEPYVLE KTYMPTHLIP
160 170 180 190 200
GINDDVLHDS IYNHITNVLQ LKIAGTHRKI RACKSDHIDQ QHLGCKQDDP
210 220 230
ILEVEHVGFL DTGIPFEYSF SRHRHDKFVV TSVNIRR
Length:237
Mass (Da):27,374
Last modified:July 1, 1997 - v1
Checksum:iB5025AECA4C5B8E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88802 Genomic DNA. Translation: BAA19709.1.
AL009126 Genomic DNA. Translation: CAB12404.1.
PIRiE69785.
RefSeqiNP_388466.1. NC_000964.3.
WP_003234096.1. NZ_JNCM01000031.1.

Genome annotation databases

EnsemblBacteriaiCAB12404; CAB12404; BSU05850.
GeneIDi939879.
KEGGibsu:BSU05850.
PATRICi18972786. VBIBacSub10457_0614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88802 Genomic DNA. Translation: BAA19709.1.
AL009126 Genomic DNA. Translation: CAB12404.1.
PIRiE69785.
RefSeqiNP_388466.1. NC_000964.3.
WP_003234096.1. NZ_JNCM01000031.1.

3D structure databases

ProteinModelPortaliO05509.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003278.

Proteomic databases

PaxDbiO05509.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12404; CAB12404; BSU05850.
GeneIDi939879.
KEGGibsu:BSU05850.
PATRICi18972786. VBIBacSub10457_0614.

Phylogenomic databases

eggNOGiENOG4108TZY. Bacteria.
COG2188. LUCA.
HOGENOMiHOG000228720.
InParanoidiO05509.
KOiK03492.
OMAiPVYYVVR.
PhylomeDBiO05509.

Enzyme and pathway databases

BioCyciBSUB:BSU05850-MONOMER.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.40.1410.10. 1 hit.
InterProiIPR028978. Chorismate_lyase_/UTRA_dom.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011663. UTRA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00392. GntR. 1 hit.
PF07702. UTRA. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00345. HTH_GNTR. 1 hit.
SM00866. UTRA. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF64288. SSF64288. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGMUR_BACSU
AccessioniPrimary (citable) accession number: O05509
Secondary accession number(s): Q797D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: July 1, 1997
Last modified: October 5, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.