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Protein

RNA polymerase sigma factor RpoH

Gene

rpoH

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi253 – 272H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processStress response, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor RpoHUniRule annotation
Alternative name(s):
RNA polymerase sigma-32 factorUniRule annotation
Gene namesi
Name:rpoHUniRule annotation
Ordered Locus Names:BU025
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000939511 – 284RNA polymerase sigma factor RpoHAdd BLAST284

Interactioni

Subunit structurei

Interacts with the RNA polymerase core enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi107806.BU025

Structurei

3D structure databases

ProteinModelPortaliO05385
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni53 – 122Sigma-70 factor domain-2UniRule annotationAdd BLAST70
Regioni228 – 280Sigma-70 factor domain-4UniRule annotationAdd BLAST53

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi77 – 80Interaction with polymerase core subunit RpoC4

Sequence similaritiesi

Belongs to the sigma-70 factor family. RpoH subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DEK Bacteria
COG0568 LUCA
HOGENOMiHOG000270269
KOiK03089
OMAiYQRWLAE

Family and domain databases

Gene3Di1.10.10.101 hit
HAMAPiMF_00961 Sigma70_RpoH, 1 hit
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR007627 RNA_pol_sigma70_r2
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR012759 RNA_pol_sigma_RpoH_proteobac
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 1 hit
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02392 rpoH_proteo, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

O05385-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINKVQILSV TPPGNLDAYI RIANLWPMLS IEEEKKLTKR LRYNGDLDAA
60 70 80 90 100
KTLILSHLRF VIHISRNYSG YGLLQSDLIQ EGNIGLMKAV RRFNPEIGVR
110 120 130 140 150
LVSFAVHWIK SEIHEYVLRN WRIVKVATTK SQRKLFFNLR KTKKRLGWFN
160 170 180 190 200
EEEIQIVARE LGVSSRDVRE MESRMSAQDV AFNPSPEEHC DSKTNSSIQY
210 220 230 240 250
LQDKTSNFAN GVEQDNWEEH AANKLSSALL RLDERSRHII HARWLDKNKK
260 270 280
NTLQNIANNY GISAERVRQL EKNAMKKLKL AIEA
Length:284
Mass (Da):32,937
Last modified:July 1, 1997 - v1
Checksum:i8BEE7BC9E0F18300
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35400 Genomic DNA Translation: AAB51433.1
BA000003 Genomic DNA Translation: BAB12752.1
RefSeqiNP_239866.1, NC_002528.1
WP_009873986.1, NC_002528.1

Genome annotation databases

EnsemblBacteriaiBAB12752; BAB12752; BAB12752
GeneIDi1109533
KEGGibuc:BU025
PATRICifig|107806.10.peg.37

Similar proteinsi

Entry informationi

Entry nameiRPOH_BUCAI
AccessioniPrimary (citable) accession number: O05385
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: July 1, 1997
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome