O05309 (O05309_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL CAB07831.1

Gene names

Ordered Locus Names:

MT1246, Rv1208

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 3E25 PDB 3E26 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	UDP-glucose metabolic process Inferred from direct assay. Source: MTBBASE growth Inferred from mutant phenotype. Source: MTBBASE protein homotrimerization Inferred from physical interaction. Source: MTBBASE
Molecular function	magnesium ion binding Inferred from direct assay Ref.3. Source: MTBBASE protein homodimerization activity Inferred from physical interaction. Source: MTBBASE transferase activity, transferring hexosyl groups Inferred from direct assay. Source: MTBBASE
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O05309 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 7CE4AE274C1A23BA	FASTA	324	34,379
	10 20 30 40 50 60 MTASELVAGD LAGGRAPGAL PLDTTWHRPG WTIGELEAAK AGRTISVVLP ALNEEATIES 70 80 90 100 110 120 VIDSISPLVD GLVDELIVLD SGSTDDTEIR AIASGARVVS REQALPEVPV RPGKGEALWR 130 140 150 160 170 180 SLAATSGDIV VFIDSDLINP HPLFVPWLVG PLLTGEGIQL VKSFYRRPLQ VSDVTSGVCA 190 200 210 220 230 240 TGGGRVTELV ARPLLAALRP ELGCVLQPLS GEYAASRELL TSLPFAPGYG VEIGLLIDTF 250 260 270 280 290 300 DRLGLDAIAQ VNLGVRAHRN RPLDELGAMS RQVIATLLSR CGIPDSGVGL TQFLPGGPDD 310 320 SDYTRHTWPV SLVDRPPMKV MRPR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
[3]	"Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis." Pereira P.J., Empadinhas N., Albuquerque L., Sa-Moura B., da Costa M.S., Macedo-Ribeiro S. PLoS ONE 3:e3748-e3748(2008) [PubMed: 19015727] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000516 Genomic DNA. Translation: AAK45503.1.
BX842575 Genomic DNA. Translation: CAB07831.1.

PIR

F70609.

RefSeq

NP_215724.1. NC_000962.2.
NP_335689.1. NC_002755.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3E25	X-ray	2.70	A	1-324	[»]
3E26	X-ray	2.50	A	1-324	[»]

ProteinModelPortal

O05309.

ModBase

Search...

Protein family/group databases

CAZy

GT81. Glycosyltransferase Family 81.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBMYCT00000001567; EBMYCP00000001567; EBMYCG00000001567.
EBMYCT00000070460; EBMYCP00000068519; EBMYCG00000070455.

GeneID

886085.
924822.

GenomeReviews

Gene locus MT1246 in contig AE000516_GR.
Gene locus Rv1208 in contig AL123456_GR.

KEGG

mtc:MT1246.
mtu:Rv1208.

PATRIC

18124508. VBIMycTub22151_1373.

TIGR

MT1246.

Organism-specific databases

TubercuList

Rv1208.

Phylogenomic databases

GeneTree

EBGT00050000015645.

HOGENOM

HBG752660.

OMA

LGVMSRQ.

ProtClustDB

PRK13915.

Family and domain databases

InterPro

IPR001173. Glyco_trans_2.
[Graphical view]

KO

K13693.

Pfam

PF00535. Glycos_transf_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O05309_MYCTU

Accession

Primary (citable) accession number: O05309
Secondary accession number(s): Q7D8M0

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)