O05240 (YUGK_BACSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable NADH-dependent butanol dehydrogenase 2
EC=1.1.1.-

Gene names

Name:	yugK
Ordered Locus Names:	BSU31360

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Pathway	Alcohol metabolism; butanol biosynthesis.
Sequence similarities	Belongs to the iron-containing alcohol dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 390	390	Probable NADH-dependent butanol dehydrogenase 2		PRO_0000087820

Sequences

	Sequence		Length	Mass (Da)
	O05240 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 027D3CD5CD8BA52F	FASTA	390	43,406
	10 20 30 40 50 60 MENFTYYNPT KLIFGKGQLE QLRKEFKRYG KNVLLVYGGG SIKRNGLYDQ VTGILKEEGA 70 80 90 100 110 120 VVHELSGVEP NPRLATVEKG IGLCREHDID FLLAVGGGSV IDCTKAIAAG VKYDGDAWDI 130 140 150 160 170 180 FSKKVTAEDA LPFGTVLTLA ATGSEMNPDS VITNWETNEK FVWGSNVTHP RFSILDPENT 190 200 210 220 230 240 FTVPENQTVY GMVDMMSHVF EQYFHNVENT PLQDRMCFAV LQTVIETAPK LLEDLENYEL 250 260 270 280 290 300 RETILYAGTI ALNGTLQMGY FGDWASHTME HAVSAVYDIP HAGGLAILFP NWMRYTLDTN 310 320 330 340 350 360 VGRFKNLMLN MFDIDTEGKT DKEIALEGID KLSAFWTSLG APSRLADYNI GEEKLELIAD 370 380 390 IAAKEMEHGG FGNFQKLNKD DVLAILRASL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai)." Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H., Duesterhoeft A., Pohl T.M., Weitzenegger T. Microbiology 143:2769-2774(1997) [PubMed: 9274030] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z93934 Genomic DNA. Translation: CAB07923.1. AL009126 Genomic DNA. Translation: CAB15125.1.
PIR	B70011.
RefSeq	NP_391014.1. NC_000964.3.
3D structure databases
ProteinModelPortal	O05240.
SMR	O05240. Positions 1-390.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000000992; EBBACP00000000992; EBBACG00000000990.
GeneID	938844.
GenomeReviews	Gene locus BSU31360 in contig AL009126_GR.
KEGG	bsu:BSU31360.
NMPDR	fig|224308.1.peg.3139.
PATRIC	18978240. VBIBacSub10457_3283.
Organism-specific databases
GenoList	BSU31360.
Phylogenomic databases
GeneTree	EBGT00050000000021.
HOGENOM	HBG742415.
OMA	ILYAGTI.
PhylomeDB	O05240.
ProtClustDB	CLSK2460951.
Enzyme and pathway databases
BioCyc	BSUB:BSU31360-MONOMER.
Family and domain databases
InterPro	IPR001670. ADH_Fe. IPR018211. ADH_Fe_CS. [Graphical view]
Pfam	PF00465. Fe-ADH. 1 hit. [Graphical view]
PROSITE	PS00913. ADH_IRON_1. 1 hit. PS00060. ADH_IRON_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YUGK_BACSU

Accession

Primary (citable) accession number: O05240

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 1, 1997
Last modified:	January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program