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Protein

VCP-like ATPase

Gene

vat

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Temperature dependencei

Optimum temperature is 70 degrees Celsius.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi231 – 238ATPSequence analysis8
Nucleotide bindingi508 – 515ATPSequence analysis8

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTACI273075:G1GT7-938-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
VCP-like ATPase
Gene namesi
Name:vat
Ordered Locus Names:Ta0840
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000846241 – 745VCP-like ATPaseAdd BLAST745

Proteomic databases

PRIDEiO05209

Interactioni

Subunit structurei

Homohexamer. Forms a ring-shaped particle.

Protein-protein interaction databases

STRINGi273075.Ta0840

Structurei

Secondary structure

1745
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 12Combined sources7
Beta strandi21 – 26Combined sources6
Helixi28 – 32Combined sources5
Beta strandi41 – 56Combined sources16
Turni60 – 64Combined sources5
Beta strandi65 – 68Combined sources4
Helixi71 – 77Combined sources7
Beta strandi84 – 90Combined sources7
Beta strandi96 – 103Combined sources8
Turni106 – 109Combined sources4
Helixi116 – 124Combined sources9
Beta strandi149 – 160Combined sources12
Beta strandi169 – 172Combined sources4
Beta strandi177 – 179Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1CZ4NMR-A1-183[»]
1CZ5NMR-A1-183[»]
5G4Felectron microscopy7.00A/B/C/D/E/P1-726[»]
5G4Gelectron microscopy7.80A/B/C/D/E/F6-726[»]
5VC7electron microscopy3.90A/C/D/E/F/G183-745[»]
5VCAelectron microscopy3.90M/N/O/P/Q/R183-745[»]
ProteinModelPortaliO05209
SMRiO05209
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO05209

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family. CDC48 subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01308 Archaea
COG0464 LUCA
HOGENOMiHOG000223224
KOiK13525
OMAiKARDANR
OrthoDBiPOG093Z00GN

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR005938 AAA_ATPase_CDC48
IPR009010 Asp_de-COase-like_dom_sf
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR004201 Cdc48_dom2
IPR029067 CDC48_domain_2-like_sf
IPR003338 CDC4_N-term_subdom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 2 hits
PF02933 CDC48_2, 1 hit
PF02359 CDC48_N, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01072 CDC48_2, 1 hit
SM01073 CDC48_N, 1 hit
SUPFAMiSSF50692 SSF50692, 1 hit
SSF52540 SSF52540, 2 hits
SSF54585 SSF54585, 1 hit
TIGRFAMsiTIGR01243 CDC48, 1 hit
PROSITEiView protein in PROSITE
PS00674 AAA, 2 hits

Sequencei

Sequence statusi: Complete.

O05209-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESNNGIILR VAEANSTDPG MSRVRLDESS RRLLDAEIGD VVEIEKVRKT
60 70 80 90 100
VGRVYRARPE DENKGIVRID SVMRNNCGAS IGDKVKVRKV RTEIAKKVTL
110 120 130 140 150
APIIRKDQRL KFGEGIEEYV QRALIRRPML EQDNISVPGL TLAGQTGLLF
160 170 180 190 200
KVVKTLPSKV PVEIGEETKI EIREEPASEV LEEVSRISYE DIGGLSEQLG
210 220 230 240 250
KIREMIELPL KHPELFERLG ITPPKGVILY GPPGTGKTLI ARAVANESGA
260 270 280 290 300
NFLSINGPEI MSKYYGQSEQ KLREIFSKAE ETAPSIIFID EIDSIAPKRE
310 320 330 340 350
EVQGEVERRV VAQLLTLMDG MKERGHVIVI GATNRIDAID PALRRPGRFD
360 370 380 390 400
REIEIGVPDR NGRKEILMIH TRNMPLGMSE EEKNKFLEEM ADYTYGFVGA
410 420 430 440 450
DLAALVRESA MNALRRYLPE IDLDKPIPTE ILEKMVVTED DFKNALKSIE
460 470 480 490 500
PSSLREVMVE VPNVHWDDIG GLEDVKREIK ETVELPLLKP DVFKRLGIRP
510 520 530 540 550
SKGFLLYGPP GVGKTLLAKA VATESNANFI SIKGPEVLSK WVGESEKAIR
560 570 580 590 600
EIFKKAKQVA PAIVFLDEID SIAPRRGTTS DSGVTERIVN QLLTSLDGIE
610 620 630 640 650
VMNGVVVIGA TNRPDIMDPA LLRAGRFDKL IYIPPPDKEA RLSILKVHTK
660 670 680 690 700
NMPLAPDVDL NDIAQRTEGY VGADLENLCR EAGMNAYREN PDATSVSQKN
710 720 730 740
FLDALKTIRP SVDEEVIKFY RTLSETMSKS VSERRKQLQD QGLYL
Length:745
Mass (Da):83,139
Last modified:July 1, 1997 - v1
Checksum:iB195EB2044FCF1F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78072 Genomic DNA Translation: AAC45089.1
AL445065 Genomic DNA Translation: CAC11969.1
PIRiT37458
RefSeqiWP_010901251.1, NC_002578.1

Genome annotation databases

EnsemblBacteriaiCAC11969; CAC11969; CAC11969
GeneIDi1456383
KEGGitac:Ta0840

Similar proteinsi

Entry informationi

Entry nameiVAT_THEAC
AccessioniPrimary (citable) accession number: O05209
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: March 28, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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