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Protein

VCP-like ATPase

Gene

vat

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Temperature dependencei

Optimum temperature is 70 degrees Celsius.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi231 – 2388ATPSequence analysis
Nucleotide bindingi508 – 5158ATPSequence analysis

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
VCP-like ATPase
Gene namesi
Name:vat
Ordered Locus Names:Ta0840
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 745745VCP-like ATPasePRO_0000084624Add
BLAST

Proteomic databases

PRIDEiO05209.

Interactioni

Subunit structurei

Homohexamer. Forms a ring-shaped particle.

Protein-protein interaction databases

STRINGi273075.Ta0840.

Structurei

Secondary structure

1
745
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 127Combined sources
Beta strandi21 – 266Combined sources
Helixi28 – 325Combined sources
Beta strandi41 – 5616Combined sources
Turni60 – 645Combined sources
Beta strandi65 – 684Combined sources
Helixi71 – 777Combined sources
Beta strandi84 – 907Combined sources
Beta strandi96 – 1038Combined sources
Turni106 – 1094Combined sources
Helixi116 – 1249Combined sources
Beta strandi149 – 16012Combined sources
Beta strandi169 – 1724Combined sources
Beta strandi177 – 1793Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1CZ4NMR-A1-183[»]
1CZ5NMR-A1-183[»]
ProteinModelPortaliO05209.
SMRiO05209. Positions 1-183, 457-692.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO05209.

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family. CDC48 subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01308. Archaea.
COG0464. LUCA.
HOGENOMiHOG000223224.
KOiK13525.
OMAiVRESAMN.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR009010. Asp_de-COase-like_dom.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR004201. Cdc48_dom2.
IPR029067. CDC48_domain_2-like.
IPR003338. CDC4_N-term_subdom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF02933. CDC48_2. 1 hit.
PF02359. CDC48_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
SM01072. CDC48_2. 1 hit.
SM01073. CDC48_N. 1 hit.
[Graphical view]
SUPFAMiSSF50692. SSF50692. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiPS00674. AAA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O05209-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESNNGIILR VAEANSTDPG MSRVRLDESS RRLLDAEIGD VVEIEKVRKT
60 70 80 90 100
VGRVYRARPE DENKGIVRID SVMRNNCGAS IGDKVKVRKV RTEIAKKVTL
110 120 130 140 150
APIIRKDQRL KFGEGIEEYV QRALIRRPML EQDNISVPGL TLAGQTGLLF
160 170 180 190 200
KVVKTLPSKV PVEIGEETKI EIREEPASEV LEEVSRISYE DIGGLSEQLG
210 220 230 240 250
KIREMIELPL KHPELFERLG ITPPKGVILY GPPGTGKTLI ARAVANESGA
260 270 280 290 300
NFLSINGPEI MSKYYGQSEQ KLREIFSKAE ETAPSIIFID EIDSIAPKRE
310 320 330 340 350
EVQGEVERRV VAQLLTLMDG MKERGHVIVI GATNRIDAID PALRRPGRFD
360 370 380 390 400
REIEIGVPDR NGRKEILMIH TRNMPLGMSE EEKNKFLEEM ADYTYGFVGA
410 420 430 440 450
DLAALVRESA MNALRRYLPE IDLDKPIPTE ILEKMVVTED DFKNALKSIE
460 470 480 490 500
PSSLREVMVE VPNVHWDDIG GLEDVKREIK ETVELPLLKP DVFKRLGIRP
510 520 530 540 550
SKGFLLYGPP GVGKTLLAKA VATESNANFI SIKGPEVLSK WVGESEKAIR
560 570 580 590 600
EIFKKAKQVA PAIVFLDEID SIAPRRGTTS DSGVTERIVN QLLTSLDGIE
610 620 630 640 650
VMNGVVVIGA TNRPDIMDPA LLRAGRFDKL IYIPPPDKEA RLSILKVHTK
660 670 680 690 700
NMPLAPDVDL NDIAQRTEGY VGADLENLCR EAGMNAYREN PDATSVSQKN
710 720 730 740
FLDALKTIRP SVDEEVIKFY RTLSETMSKS VSERRKQLQD QGLYL
Length:745
Mass (Da):83,139
Last modified:July 1, 1997 - v1
Checksum:iB195EB2044FCF1F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78072 Genomic DNA. Translation: AAC45089.1.
AL445065 Genomic DNA. Translation: CAC11969.1.
PIRiT37458.
RefSeqiWP_010901251.1. NC_002578.1.

Genome annotation databases

EnsemblBacteriaiCAC11969; CAC11969; CAC11969.
GeneIDi1456383.
KEGGitac:Ta0840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78072 Genomic DNA. Translation: AAC45089.1.
AL445065 Genomic DNA. Translation: CAC11969.1.
PIRiT37458.
RefSeqiWP_010901251.1. NC_002578.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1CZ4NMR-A1-183[»]
1CZ5NMR-A1-183[»]
ProteinModelPortaliO05209.
SMRiO05209. Positions 1-183, 457-692.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273075.Ta0840.

Proteomic databases

PRIDEiO05209.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC11969; CAC11969; CAC11969.
GeneIDi1456383.
KEGGitac:Ta0840.

Phylogenomic databases

eggNOGiarCOG01308. Archaea.
COG0464. LUCA.
HOGENOMiHOG000223224.
KOiK13525.
OMAiVRESAMN.

Miscellaneous databases

EvolutionaryTraceiO05209.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR009010. Asp_de-COase-like_dom.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR004201. Cdc48_dom2.
IPR029067. CDC48_domain_2-like.
IPR003338. CDC4_N-term_subdom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF02933. CDC48_2. 1 hit.
PF02359. CDC48_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
SM01072. CDC48_2. 1 hit.
SM01073. CDC48_N. 1 hit.
[Graphical view]
SUPFAMiSSF50692. SSF50692. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiPS00674. AAA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVAT_THEAC
AccessioniPrimary (citable) accession number: O05209
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.