O04996 (SODC_SOLCS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1

Gene names

Name:

SODCC

Organism

Solidago canadensis var. scabra (Tall goldenrod) (Solidago altissima)

Taxonomic identifier

59294 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Astereae › North American clade › Solidago › Solidago canadensis

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 153	152	Superoxide dismutase [Cu-Zn]		PRO_0000164155
Sites
	Metal binding	46	1	Copper; catalytic By similarity
	Metal binding	48	1	Copper; catalytic By similarity
	Metal binding	63	1	Copper; catalytic By similarity
	Metal binding	63	1	Zinc; structural By similarity
	Metal binding	71	1	Zinc; structural By similarity
	Metal binding	80	1	Zinc; structural By similarity
	Metal binding	83	1	Zinc; structural By similarity
	Metal binding	120	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	57 ↔ 146		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O04996 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 1746763A92F42F88	FASTA	153	15,436
	10 20 30 40 50 60 MVKAVAVLSS SEGVSGTIFF SQEAEGAPTT VTGDLSGLKP GPHGFHVHAL GDTTNGCMST 70 80 90 100 110 120 GPHYNPHGKD HGAPDDEHRH AGDLGNVTVG EDGTAKFTIV DKQIPLIGAQ SIIGRAVVVH 130 140 150 ADPDDLGKGG HELSKTTGNA GGRVACGIIG LQG

References

[1]	"Different transcriptional regulation of cytosolic and plastidic Cu/Zn-superoxide dismutase genes in Solidago altissima (Asteraceae)." Murai R., Murai K. Plant Sci. 120:71-79(1996) Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Nonoichi-Machi.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D49485 mRNA. Translation: BAA19674.1.
3D structure databases
ProteinModelPortal	O04996.
SMR	O04996. Positions 1-153.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_SOLCS

Accession

Primary (citable) accession number: O04996

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	January 23, 2007
Last modified:	March 6, 2013
This is version 77 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program