Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O04937 (DHEA_NICPL) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate dehydrogenase A

Short name=GDH A
EC=1.4.1.3
Gene names
Name:GDHA
OrganismNicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Taxonomic identifier4092 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutamate dehydrogenase [NAD(P)+] activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase A
PRO_0000182750

Sites

Active site1021 By similarity

Sequences

Sequence LengthMass (Da)Tools
O04937 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 5CCF132AF2103904

FASTA41144,796
        10         20         30         40         50         60 
MNALAATNRN FRQAARILGL DSKLEKSLLI PFREIKVECT IPKDDGTLVS YVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDLDEV NALAQLMTWK TAVADIPYGG AKGGIGCKPK DLSKSELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGINTDVPA PDMGTNAQTM AWILDEYSKF HGHSPAIVTG KPIDLGGSLG 

       190        200        210        220        230        240 
REAATGRGVV YATEALLAEY GKNIKDLTFA IQGFGNVGAW AAKLIHERGG KVIAVSDITG 

       250        260        270        280        290        300 
AVKNPNGLDI PALLNHKEAT GKLIDFSGGD VMNSDEVLTH ECDVLIPCAL GGVLNRENAD 

       310        320        330        340        350        360 
NVKAKFIIEA ANHPTDPEAD EILCKKGIVI LPDIYANAGG VTVSYFEWVQ NIQGFMWDEE 

       370        380        390        400        410 
KVNRELRKYM TKAFHNLKNM CQSHNCSLRM GAFTLGVNRV ARATTLRGWE A 

« Hide

References

[1]"Isolation and characterization of two cDNA clones encoding for glutamate dehydrogenase in Nicotiana plumbaginifolia."
Ficarelli A., Tassi F., Restivo F.M.
Plant Cell Physiol. 40:339-342(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Leaf.
[2]"Genomic organisation of GDH genes in Nicotiana plumbaginifolia."
Restivo F.M., Panizzi N., De Monte G., Ficarelli A.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y08292 mRNA. Translation: CAA69600.1.
AJ277949 Genomic DNA. Translation: CAB94836.1.
PIRT16981.

3D structure databases

ProteinModelPortalO04937.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHEA_NICPL
AccessionPrimary (citable) accession number: O04937
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: July 9, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families