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O04931

- AGLU_BETVU

UniProt

O04931 - AGLU_BETVU

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Protein

Alpha-glucosidase

Gene
N/A
Organism
Beta vulgaris (Sugar beet)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

High activity for alpha-glucan.

Catalytic activityi

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei469 – 46911 Publication
Active sitei472 – 4721By similarity
Active sitei568 – 5681Proton donorBy similarity

GO - Molecular functioni

  1. alpha-1,4-glucosidase activity Source: UniProtKB
  2. carbohydrate binding Source: InterPro
  3. maltose alpha-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-glucosidase (EC:3.2.1.20)
Alternative name(s):
Maltase
OrganismiBeta vulgaris (Sugar beet)
Taxonomic identifieri161934 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeBeta

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence AnalysisAdd
BLAST
Chaini29 – 913885Alpha-glucosidasePRO_0000018582Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi54 – 541N-linked (GlcNAc...)Sequence Analysis
Glycosylationi404 – 4041N-linked (GlcNAc...)Sequence Analysis
Glycosylationi495 – 4951N-linked (GlcNAc...)Sequence Analysis
Glycosylationi517 – 5171N-linked (GlcNAc...)Sequence Analysis
Glycosylationi728 – 7281N-linked (GlcNAc...)Sequence Analysis
Glycosylationi823 – 8231N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Glycoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O04931-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERSKLPRYI CPTLAVVLPL VLCMVVEGAT TSKNDNQGEA IGYGYQVKNA
60 70 80 90 100
KVDNSTGKSL TALLQLIRNS PVYGPDIHFL SFTASFEEDD TLRIRFTDAN
110 120 130 140 150
NRRWEIPNEV LPRPPPPPSP PPLSSLQHLP KPIPQNQPTT TVLSHPHSDL
160 170 180 190 200
AFTLFHTTPF GFTIYRKSTH DVLFDATPIP SNPTTFLIYK DQYLQLSSSL
210 220 230 240 250
PAQQAHLYGL GEHTKPTFQL AHNQILTLWN ADIASFNRDL NLYGSHPFYM
260 270 280 290 300
DVRSSPMVGS THGVFLLNSN GMDVEYTGDR ITYKVIGGII DLYIFAGRTP
310 320 330 340 350
EMVLDQYTKL IGRPAPMPYW AFGFHQCRWG YRDVNEIETV VDKYAEARIP
360 370 380 390 400
LEVMWTDIDY MDAFKDFTLD PVHFPLDKMQ QFVTKLHRNG QRYVPILDPG
410 420 430 440 450
INTNKSYGTF IRGMQSNVFI KRNGNPYLGS VWPGPVYYPD FLDPAARSFW
460 470 480 490 500
VDEIKRFRDI LPIDGIWIDM NEASNFITSA PTPGSTLDNP PYKINNSGGR
510 520 530 540 550
VPINSKTIPA TAMHYGNVTE YNAHNLYGFL ESQATREALV RPATRGPFLL
560 570 580 590 600
SRSTFAGSGK YTAHWTGDNA ARWDDLQYSI PTMLNFGLFG MPMIGADICG
610 620 630 640 650
FAESTTEELC CRWIQLGAFY PFSRDHSARD TTHQELYLWE SVAASARTVL
660 670 680 690 700
GLRYELLPYY YTLMYDANLR GSPIARPLSF TFPDDVATYG ISSQFLIGRG
710 720 730 740 750
IMVSPVLQPG SSIVNAYSPR GNWVSLSNYT SSVSVSAGTY VSLSAPPDHI
760 770 780 790 800
NVHIHEGNIV AMQGEAMTTQ AARSTPFHLL VVMSDHVAST GELFLDNGIE
810 820 830 840 850
MDIGGPGGKW TLVRFFAESG INNLTISSEV VNRGYAMSQR WVMDKITILG
860 870 880 890 900
LKRRVKIKEY TVQKDAGAIK VKGLGRRTSS HNQGGFFVSV ISDLRQLVGQ
910
AFKLELEFEG ATR
Length:913
Mass (Da):102,117
Last modified:July 1, 1997 - v1
Checksum:i02AC4F0B505369CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89615 mRNA. Translation: BAA20343.1.
PIRiJC5463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89615 mRNA. Translation: BAA20343.1 .
PIRi JC5463.

3D structure databases

ModBasei Search...
MobiDBi Search...

Chemistry

ChEMBLi CHEMBL4348.

Protein family/group databases

CAZyi GH31. Glycoside Hydrolase Family 31.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and sequencing of a cDNA encoding alpha-glucosidase from sugar beet."
    Matsui H., Iwanami S., Ito H., Mori H., Honma M., Chiba S.
    Biosci. Biotechnol. Biochem. 61:875-880(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Strain: cv. NK-152.
  2. "Chemical modification and amino acid sequence of active site in sugar beet alpha-glucosidase."
    Iwanami S., Matsui H., Kimura A., Ito H., Mori H., Honma M., Chiba S.
    Biosci. Biotechnol. Biochem. 59:459-463(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACTIVE SITE, PROTEIN SEQUENCE OF 464-472.

Entry informationi

Entry nameiAGLU_BETVU
AccessioniPrimary (citable) accession number: O04931
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3