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Protein

Nitrate reductase

Gene

NR3

Organism
Solanum tuberosum (Potato)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • FADSAAS annotation
  • Mo-molybdopterinUniRule annotationNote: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi188MolybdenumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseSAAS annotation
Biological processNitrate assimilationUniRule annotation
LigandFADSAAS annotation, Flavoprotein, HemeSAAS annotation, Iron, Metal-binding, MolybdenumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrate reductaseUniRule annotation
Gene namesi
Name:NR3Imported
OrganismiSolanum tuberosum (Potato)Imported
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Expressioni

Gene expression databases

ExpressionAtlasiO04926 baseline

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO04926
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini536 – 611Cytochrome b5 heme-bindingInterPro annotationAdd BLAST76
Domaini654 – 766FAD-binding FR-typeInterPro annotationAdd BLAST113

Sequence similaritiesi

Belongs to the nitrate reductase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0534 Eukaryota
KOG0535 Eukaryota
KOG0537 Eukaryota
COG0543 LUCA
COG2041 LUCA
COG5274 LUCA

Family and domain databases

Gene3Di3.10.120.10, 1 hit
3.90.420.10, 1 hit
InterProiView protein in InterPro
IPR001199 Cyt_B5-like_heme/steroid-bd
IPR036400 Cyt_B5-like_heme/steroid_sf
IPR018506 Cyt_B5_heme-BS
IPR017927 Fd_Rdtase_FAD-bd
IPR001709 Flavoprot_Pyr_Nucl_cyt_Rdtase
IPR014756 Ig_E-set
IPR005066 MoCF_OxRdtse_dimer
IPR008335 Mopterin_OxRdtase_euk
IPR001834 NADH-Cyt_B5_reductase
IPR012137 Nitr_rd_NADH
IPR008333 OxRdtase_FAD-bd_dom
IPR001433 OxRdtase_FAD/NAD-bd
IPR000572 OxRdtase_Mopterin-bd_dom
IPR036374 OxRdtase_Mopterin-bd_sf
IPR022407 OxRdtase_Mopterin_BS
IPR017938 Riboflavin_synthase-like_b-brl
PfamiView protein in Pfam
PF00173 Cyt-b5, 1 hit
PF00970 FAD_binding_6, 1 hit
PF03404 Mo-co_dimer, 1 hit
PF00175 NAD_binding_1, 1 hit
PF00174 Oxidored_molyb, 1 hit
PIRSFiPIRSF000233 Nitr_rd_NADH, 1 hit
PRINTSiPR00406 CYTB5RDTASE
PR00363 CYTOCHROMEB5
PR00407 EUMOPTERIN
PR00371 FPNCR
SMARTiView protein in SMART
SM01117 Cyt-b5, 1 hit
SUPFAMiSSF55856 SSF55856, 1 hit
SSF56524 SSF56524, 1 hit
SSF63380 SSF63380, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00191 CYTOCHROME_B5_1, 1 hit
PS50255 CYTOCHROME_B5_2, 1 hit
PS51384 FAD_FR, 1 hit
PS00559 MOLYBDOPTERIN_EUK, 1 hit

Sequencei

Sequence statusi: Complete.

O04926-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASVENRQF THLEPGLSGV GRNFKPRPDS PVRGCNFPPS SNHELPFQKQ
60 70 80 90 100
QNLPIYLDYS SSEDEDDDDE KNEYVQMIKK GKTELEPSIH DTRDEGTADN
110 120 130 140 150
WIQRNFSLIR LTGKHPFNSE PPLARLMHHG FITPVPLHYV RNHGPVPKAS
160 170 180 190 200
WADWSVEVTG LVKRPMKFTM DQLVNEFPSR ELPVTLVCAG NRRKEQNMVK
210 220 230 240 250
QTIGFNWGAA AVSTTVWRGV PLRPLLKRCG VHSKKKGALN ICFEGSDVLP
260 270 280 290 300
GGGGSKYGTS IKKEFAMDPS RDIIVAYMQN GEMLSPDHGF PVRMIIPGFI
310 320 330 340 350
GGRMVKWPKR IVVTTQESES YYHYKDNRVL PPHVELELAN AEAWWYKPEY
360 370 380 390 400
IINELNINSV ITTPSHEEIL PINAWTTQRP YTLRGYAYPG GGKKVTRVEV
410 420 430 440 450
TLDGGETWSV CTLDHPEKPT KYGKYWCWCF WSLEVEVLDL LRAKEIAVRA
460 470 480 490 500
IDETHNTQPE KLIWNVMGMM NNCWFRVKMK CVKPHKGEIG IVFEHPTQPG
510 520 530 540 550
NQSGGWMAKE RHLEISAVAP PTLKKSISTP FMNTASKMYS MSEVRKHNSS
560 570 580 590 600
DSAWIIVHGH IYDASRFLKD HPGGVDSILI NAGTDCTEEF DAIHSDKAKK
610 620 630 640 650
LLEDFRIGEL ITTGYTSDSS PNTSVHGSSS ISSFLAPIKE LVQTPTRSVA
660 670 680 690 700
LIPREKIPCK LVDKQSISHD VRKFKFALPS EDQVLGLPVG KHIFLCATVD
710 720 730 740 750
DKLCMRAYTP TSTVDEVGFF ELVVKVYFKG VHPKFPNGGQ MSQHLDSLPI
760 770 780 790 800
GAFLDVKGPL GHIEYQGKGN FLVHGKQKFP KKLAMIAGGT GITPVYQVIE
810 820 830 840 850
SILKDPEDDT EMYVVYANRT EDDILLKEEL DAWAEQIPDR VKVWYVVQES
860 870 880 890 900
ITEGWKYSTG FVTEAILREH IPQPSHTTLA LACGPPPMIQ FAINPNLEKM
910
GYDIKEELLV F
Length:911
Mass (Da):102,609
Last modified:July 1, 1997 - v1
Checksum:i2357AD1E4459EB6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95317 mRNA Translation: AAB52786.1
UniGeneiStu.139

Similar proteinsi

Entry informationi

Entry nameiO04926_SOLTU
AccessioniPrimary (citable) accession number: O04926
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health