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Protein

Nitrate reductase

Gene

NR3

Organism
Solanum tuberosum (Potato)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • FADSAAS annotation
  • Mo-molybdopterinSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseSAAS annotation

Keywords - Biological processi

Nitrate assimilationUniRule annotation

Keywords - Ligandi

FADSAAS annotation, Flavoprotein, HemeSAAS annotation, Iron, Metal-binding, MolybdenumSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrate reductaseUniRule annotation
Gene namesi
Name:NR3Imported
OrganismiSolanum tuberosum (Potato)Imported
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400077648.

Structurei

3D structure databases

ProteinModelPortaliO04926.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini536 – 611Cytochrome b5 heme-bindingInterPro annotationAdd BLAST76
Domaini654 – 766FAD-binding FR-typeInterPro annotationAdd BLAST113

Sequence similaritiesi

Belongs to the nitrate reductase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0534. Eukaryota.
KOG0535. Eukaryota.
KOG0537. Eukaryota.
COG0543. LUCA.
COG2041. LUCA.
COG5274. LUCA.

Family and domain databases

Gene3Di2.60.40.650. 1 hit.
3.10.120.10. 1 hit.
3.90.420.10. 1 hit.
InterProiIPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
IPR017927. Fd_Rdtase_FAD-bd.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR014756. Ig_E-set.
IPR005066. MoCF_OxRdtse_dimer.
IPR008335. Mopterin_OxRdtase_euk.
IPR001834. NADH-Cyt_B5_reductase.
IPR012137. Nitr_rd_NADH.
IPR008333. OxRdtase_FAD-bd_dom.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR000572. OxRdtase_Mopterin-bd_dom.
IPR022407. OxRdtase_Mopterin_BS.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
PF00970. FAD_binding_6. 1 hit.
PF03404. Mo-co_dimer. 1 hit.
PF00175. NAD_binding_1. 1 hit.
PF00174. Oxidored_molyb. 1 hit.
[Graphical view]
PIRSFiPIRSF000233. Nitr_rd_NADH. 1 hit.
PRINTSiPR00406. CYTB5RDTASE.
PR00363. CYTOCHROMEB5.
PR00407. EUMOPTERIN.
PR00371. FPNCR.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
SSF56524. SSF56524. 1 hit.
SSF63380. SSF63380. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
PS51384. FAD_FR. 1 hit.
PS00559. MOLYBDOPTERIN_EUK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O04926-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASVENRQF THLEPGLSGV GRNFKPRPDS PVRGCNFPPS SNHELPFQKQ
60 70 80 90 100
QNLPIYLDYS SSEDEDDDDE KNEYVQMIKK GKTELEPSIH DTRDEGTADN
110 120 130 140 150
WIQRNFSLIR LTGKHPFNSE PPLARLMHHG FITPVPLHYV RNHGPVPKAS
160 170 180 190 200
WADWSVEVTG LVKRPMKFTM DQLVNEFPSR ELPVTLVCAG NRRKEQNMVK
210 220 230 240 250
QTIGFNWGAA AVSTTVWRGV PLRPLLKRCG VHSKKKGALN ICFEGSDVLP
260 270 280 290 300
GGGGSKYGTS IKKEFAMDPS RDIIVAYMQN GEMLSPDHGF PVRMIIPGFI
310 320 330 340 350
GGRMVKWPKR IVVTTQESES YYHYKDNRVL PPHVELELAN AEAWWYKPEY
360 370 380 390 400
IINELNINSV ITTPSHEEIL PINAWTTQRP YTLRGYAYPG GGKKVTRVEV
410 420 430 440 450
TLDGGETWSV CTLDHPEKPT KYGKYWCWCF WSLEVEVLDL LRAKEIAVRA
460 470 480 490 500
IDETHNTQPE KLIWNVMGMM NNCWFRVKMK CVKPHKGEIG IVFEHPTQPG
510 520 530 540 550
NQSGGWMAKE RHLEISAVAP PTLKKSISTP FMNTASKMYS MSEVRKHNSS
560 570 580 590 600
DSAWIIVHGH IYDASRFLKD HPGGVDSILI NAGTDCTEEF DAIHSDKAKK
610 620 630 640 650
LLEDFRIGEL ITTGYTSDSS PNTSVHGSSS ISSFLAPIKE LVQTPTRSVA
660 670 680 690 700
LIPREKIPCK LVDKQSISHD VRKFKFALPS EDQVLGLPVG KHIFLCATVD
710 720 730 740 750
DKLCMRAYTP TSTVDEVGFF ELVVKVYFKG VHPKFPNGGQ MSQHLDSLPI
760 770 780 790 800
GAFLDVKGPL GHIEYQGKGN FLVHGKQKFP KKLAMIAGGT GITPVYQVIE
810 820 830 840 850
SILKDPEDDT EMYVVYANRT EDDILLKEEL DAWAEQIPDR VKVWYVVQES
860 870 880 890 900
ITEGWKYSTG FVTEAILREH IPQPSHTTLA LACGPPPMIQ FAINPNLEKM
910
GYDIKEELLV F
Length:911
Mass (Da):102,609
Last modified:July 1, 1997 - v1
Checksum:i2357AD1E4459EB6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95317 mRNA. Translation: AAB52786.1.
UniGeneiStu.139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95317 mRNA. Translation: AAB52786.1.
UniGeneiStu.139.

3D structure databases

ProteinModelPortaliO04926.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400077648.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0534. Eukaryota.
KOG0535. Eukaryota.
KOG0537. Eukaryota.
COG0543. LUCA.
COG2041. LUCA.
COG5274. LUCA.

Family and domain databases

Gene3Di2.60.40.650. 1 hit.
3.10.120.10. 1 hit.
3.90.420.10. 1 hit.
InterProiIPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
IPR017927. Fd_Rdtase_FAD-bd.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR014756. Ig_E-set.
IPR005066. MoCF_OxRdtse_dimer.
IPR008335. Mopterin_OxRdtase_euk.
IPR001834. NADH-Cyt_B5_reductase.
IPR012137. Nitr_rd_NADH.
IPR008333. OxRdtase_FAD-bd_dom.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR000572. OxRdtase_Mopterin-bd_dom.
IPR022407. OxRdtase_Mopterin_BS.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
PF00970. FAD_binding_6. 1 hit.
PF03404. Mo-co_dimer. 1 hit.
PF00175. NAD_binding_1. 1 hit.
PF00174. Oxidored_molyb. 1 hit.
[Graphical view]
PIRSFiPIRSF000233. Nitr_rd_NADH. 1 hit.
PRINTSiPR00406. CYTB5RDTASE.
PR00363. CYTOCHROMEB5.
PR00407. EUMOPTERIN.
PR00371. FPNCR.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
SSF56524. SSF56524. 1 hit.
SSF63380. SSF63380. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
PS51384. FAD_FR. 1 hit.
PS00559. MOLYBDOPTERIN_EUK. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO04926_SOLTU
AccessioniPrimary (citable) accession number: O04926
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.