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O04895 (BADH_AMAHP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase, chloroplastic

Short name=BADH
EC=1.2.1.8
Gene names
Name:BADH4
OrganismAmaranthus hypochondriacus (Prince-of-Wales feather)
Taxonomic identifier28502 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeAmaranthus

Protein attributes

Sequence length501 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH.

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.

Subunit structure

Homodimer By similarity.

Subcellular location

Plastidchloroplast.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycine betaine biosynthetic process from choline

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 77Chloroplast Potential
Chain8 – 501494Betaine aldehyde dehydrogenase, chloroplastic
PRO_0000007178

Regions

Nucleotide binding238 – 2436NAD By similarity

Sites

Active site2601Proton acceptor By similarity
Active site2941Nucleophile By similarity
Site1621Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
O04895 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: D5065A91BFC0D37E

FASTA50154,504
        10         20         30         40         50         60 
MAIRVPSRQL FIDGEWREPI KKNRIPIINP STEEIIGDIP AATAEDVELA VAAARRALKR 

        70         80         90        100        110        120 
NKGEDWASAS GAHRAKYLRA IAAKITEKKD YFAKLEAMDC GKPLDEAARD IDDVAGCFEY 

       130        140        150        160        170        180 
YADQAEALDA KQKAPIALPM DTFKCHVLKQ PIGVVGLISP WNYPLLMATW KVAPALAAGC 

       190        200        210        220        230        240 
SAVLKPSELA SVTCLELAEV CREVGLPPGV LNILTGLGPE AGGPLACHPD VDKVAFTGST 

       250        260        270        280        290        300 
ATGSKVMSSA AQLVKPVTLE LGGKSPIVIF EDVDLDKAAE WTAFGCFWTN GQICSATSRL 

       310        320        330        340        350        360 
LVHESIAAEF LDRLVKWCKN IKISDPFEEG CRLGPVVSKS QYEKVLKFIS TAKSEGATIL 

       370        380        390        400        410        420 
CGGSRPEHLK KGYYVEPTII SDVSTSMQIW REEVFGPVLC QKTFGSEDEA IELANDTQYG 

       430        440        450        460        470        480 
LGAAVLSKDL DRCERITKAL EVGAVWVNCS QPCFTQAPWG GTKRSGFGRE LGEWGIENYL 

       490        500 
NIKQVTRDTS TDEPWGWYKS P 

« Hide

References

[1]"Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth. Expression in leaves under short-term exposure to osmotic stress or abscisic acid."
Legaria J., Rajsbaum R., Munoz-Clares R.A., Villegas-Sepulveda N., Simpson J., Iturriaga G.
Gene 218:69-76(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF000132 Genomic DNA. Translation: AAB58165.1.

3D structure databases

ProteinModelPortalO04895.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00529; UER00386.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBADH_AMAHP
AccessionPrimary (citable) accession number: O04895
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways