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O04867 (GLNA1_ALNGL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

EC=6.3.1.2
Alternative name(s):
GS(1)
Glutamate--ammonia ligase
Gene names
Name:GLN1
OrganismAlnus glutinosa (European alder) (Betula alnus var. glutinosa)
Taxonomic identifier3517 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeAlnus

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm.

Tissue specificity

Found at highest levels in root nodules.

Miscellaneous

Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Biological processNitrogen fixation
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

nitrogen fixation

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 356356Glutamine synthetase
PRO_0000153167

Sequences

Sequence LengthMass (Da)Tools
O04867 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 5A768FF0C13B5A33

FASTA35639,324
        10         20         30         40         50         60 
MSLLSDLINL NLSDATDKVI AEYIWIGGSG TDLRSKARTL TGPVNHPSKL PKWNYDGSST 

        70         80         90        100        110        120 
GQAPGEDSEV IYILRQFFKD PFRRGNNILV ICDTYTPAGE PIPTNKRHGA AKIFSHPEVV 

       130        140        150        160        170        180 
AEVPWYGIEQ EYTLLQKDVK WPLGWPVGGY PGPQGPYYCG IGADKAWGRD IVDAHYKACL 

       190        200        210        220        230        240 
YAGINISGIN GEVMPGQWEF QVGPSVGISA GDEVWAARYI LERITEIAGV VLSLDPKPIQ 

       250        260        270        280        290        300 
GDWNGAGAHT NYSTKSMRNN GGYEIIKKAI EKLGLRHKEH IAAYGEGNER RLTGRHETAD 

       310        320        330        340        350 
INTFKWGVAN RGASIRVGRD TEKEGKGYFE DRRPASNMDP YVVTSMIAET TLLWKP 

« Hide

References

[1]"Nitrogen metabolism in actinorhizal nodules of Alnus glutinosa: expression of glutamine synthetase and acetylornithine transaminase."
Guan C., Ribeiro A., Akkermans A.D.L., Jing Y., van Kammen A., Bisseling T., Pawlowski K.
Plant Mol. Biol. 32:1177-1184(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Root nodule.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y08681 mRNA. Translation: CAA69937.1.

3D structure databases

ProteinModelPortalO04867.
SMRO04867. Positions 4-355.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA1_ALNGL
AccessionPrimary (citable) accession number: O04867
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families