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O04867

- GLNA1_ALNGL

UniProt

O04867 - GLNA1_ALNGL

Protein

Glutamine synthetase

Gene

GLN1

Organism
Alnus glutinosa (European alder) (Betula alnus var. glutinosa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro
    2. nitrogen fixation Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Nitrogen fixation

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine synthetase (EC:6.3.1.2)
    Alternative name(s):
    GS(1)
    Glutamate--ammonia ligase
    Gene namesi
    Name:GLN1
    OrganismiAlnus glutinosa (European alder) (Betula alnus var. glutinosa)
    Taxonomic identifieri3517 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeAlnus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 356356Glutamine synthetasePRO_0000153167Add
    BLAST

    Expressioni

    Tissue specificityi

    Found at highest levels in root nodules.

    Interactioni

    Subunit structurei

    Homooctamer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO04867.
    SMRiO04867. Positions 4-355.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Family and domain databases

    Gene3Di3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O04867-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLLSDLINL NLSDATDKVI AEYIWIGGSG TDLRSKARTL TGPVNHPSKL    50
    PKWNYDGSST GQAPGEDSEV IYILRQFFKD PFRRGNNILV ICDTYTPAGE 100
    PIPTNKRHGA AKIFSHPEVV AEVPWYGIEQ EYTLLQKDVK WPLGWPVGGY 150
    PGPQGPYYCG IGADKAWGRD IVDAHYKACL YAGINISGIN GEVMPGQWEF 200
    QVGPSVGISA GDEVWAARYI LERITEIAGV VLSLDPKPIQ GDWNGAGAHT 250
    NYSTKSMRNN GGYEIIKKAI EKLGLRHKEH IAAYGEGNER RLTGRHETAD 300
    INTFKWGVAN RGASIRVGRD TEKEGKGYFE DRRPASNMDP YVVTSMIAET 350
    TLLWKP 356
    Length:356
    Mass (Da):39,324
    Last modified:July 1, 1997 - v1
    Checksum:i5A768FF0C13B5A33
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08681 mRNA. Translation: CAA69937.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08681 mRNA. Translation: CAA69937.1 .

    3D structure databases

    ProteinModelPortali O04867.
    SMRi O04867. Positions 4-355.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nitrogen metabolism in actinorhizal nodules of Alnus glutinosa: expression of glutamine synthetase and acetylornithine transaminase."
      Guan C., Ribeiro A., Akkermans A.D.L., Jing Y., van Kammen A., Bisseling T., Pawlowski K.
      Plant Mol. Biol. 32:1177-1184(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Root nodule.

    Entry informationi

    Entry nameiGLNA1_ALNGL
    AccessioniPrimary (citable) accession number: O04867
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3