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O04858

- PP13_TOBAC

UniProt

O04858 - PP13_TOBAC

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Protein
Serine/threonine-protein phosphatase PP1 isozyme 3
Gene
NPP3
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Manganese 1 By similarity
Metal bindingi63 – 631Manganese 1 By similarity
Metal bindingi89 – 891Manganese 1 By similarity
Metal bindingi89 – 891Manganese 2 By similarity
Metal bindingi121 – 1211Manganese 2 By similarity
Active sitei122 – 1221Proton donor By similarity
Metal bindingi170 – 1701Manganese 2 By similarity
Metal bindingi245 – 2451Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 isozyme 3 (EC:3.1.3.16)
Gene namesi
Name:NPP3
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304Serine/threonine-protein phosphatase PP1 isozyme 3
PRO_0000058813Add
BLAST

Proteomic databases

PRIDEiO04858.

Structurei

3D structure databases

ProteinModelPortaliO04858.
SMRiO04858. Positions 6-302.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O04858-1 [UniParc]FASTAAdd to Basket

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MDTAAVDRII EKLIEVRSSN PGKLVQLSES EIKQLCVASR DIFLKQPNLL    50
ESEAPIKTRG DIHGQYSDLL RLFEYGGFPP EANYLFLGDY VDRGRQSLET 100
ICLLLAYKIK YPENFFLLRG NHECASINRI YGFYDECKRR FNVKLWKSFT 150
DCFNCLPVAA LIDEKILCMH GGLSPDLSSL DQIRNLPRPT AIPDTGLLCD 200
LQRSDPGKDV KGWGMNDRGV SYTFGPDKVS EFLSKHDLDL VCRAHQVVED 250
GYEFFAESEL VTIFSAPNYC GEFDNAGAMM SVDENLLCSF QILKPAEKKN 300
KFVM 304
Length:304
Mass (Da):34,441
Last modified:July 1, 1997 - v1
Checksum:iD8A3D5D94857A452
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z93770 mRNA. Translation: CAB07805.1.
PIRiT03597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z93770 mRNA. Translation: CAB07805.1 .
PIRi T03597.

3D structure databases

ProteinModelPortali O04858.
SMRi O04858. Positions 6-302.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi O04858.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Multiple genes encoding serine/threonine protein phosphatases and their differential expression in Nicotiana tabacum."
    Suh M., Cho H., Kim Y., Liu J., Lee H.
    Plant Mol. Biol. 36:315-322(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Xanthi.

Entry informationi

Entry nameiPP13_TOBAC
AccessioniPrimary (citable) accession number: O04858
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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