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O04857 (PP12_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1 isozyme 2

EC=3.1.3.16
Gene names
Name:NPP2
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Serine/threonine-protein phosphatase PP1 isozyme 2
PRO_0000058812

Sites

Active site1291Proton donor By similarity
Metal binding681Iron By similarity
Metal binding701Iron By similarity
Metal binding961Iron By similarity
Metal binding961Manganese By similarity
Metal binding1281Manganese By similarity
Metal binding1771Manganese By similarity
Metal binding2521Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
O04857 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 4EFA9FB525B7D4C3

FASTA31035,435
        10         20         30         40         50         60 
MAQNGQGIEP AVLDDIINRL LEFRNARTVR QVQLSEAEIR SLCTASKEIF LHQPNLLELE 

        70         80         90        100        110        120 
APIKICGDIH GQYGDLLRLF EYGGFPPEAN YLFLGDYVDR GKQSLETICL LLAYKIKYPE 

       130        140        150        160        170        180 
NFFLLRGNHE CASINRIYGF YDECKRRFNV RLWKTNTDCF NCLPVAALID DKILCMHGGL 

       190        200        210        220        230        240 
SPDLTDLDEI RNLPRPTDIP DSGLLCDLLW SDPSREVKGW GMNDRGVSYT FGSDKVAEFL 

       250        260        270        280        290        300 
MQHDMDLVCR AHQVVEDGYE FFAERQLVTI FSAPNYCGEF DNAGAMMSVD ENLMCSFQIL 

       310 
KPTDRKPRFL 

« Hide

References

[1]"Multiple genes encoding serine/threonine protein phosphatases and their differential expression in Nicotiana tabacum."
Suh M., Cho H., Kim Y., Liu J., Lee H.
Plant Mol. Biol. 36:315-322(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Xanthi.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z93769 mRNA. Translation: CAB07804.1.
PIRT03596.

3D structure databases

ProteinModelPortalO04857.
SMRO04857. Positions 13-309.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO04857.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP12_TOBAC
AccessionPrimary (citable) accession number: O04857
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families