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O04856

- PP11_TOBAC

UniProt

O04856 - PP11_TOBAC

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Protein

Serine/threonine-protein phosphatase PP1 isozyme 1

Gene
NPP1
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi75 – 751Manganese 1 By similarity
Metal bindingi77 – 771Manganese 1 By similarity
Metal bindingi103 – 1031Manganese 1 By similarity
Metal bindingi103 – 1031Manganese 2 By similarity
Metal bindingi135 – 1351Manganese 2 By similarity
Active sitei136 – 1361Proton donor By similarity
Metal bindingi184 – 1841Manganese 2 By similarity
Metal bindingi259 – 2591Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 isozyme 1 (EC:3.1.3.16)
Gene namesi
Name:NPP1
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317Serine/threonine-protein phosphatase PP1 isozyme 1PRO_0000058811Add
BLAST

Proteomic databases

PRIDEiO04856.

Structurei

3D structure databases

ProteinModelPortaliO04856.
SMRiO04856. Positions 20-316.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O04856-1 [UniParc]FASTAAdd to Basket

« Hide

MAQNNEQQQQ GQGLIEAGVL DDIINRLLEF RNARTVRQVQ LSEAEIRSLC    50
SASREIFLQQ PNLLDLKPPI KICGDIHGQY GDLLRLFEYG GFPPEANYLF 100
LGDYVDRGKQ SLETICLLLA YKIKYPENFF LLRGNHECAS INRIYGFYDE 150
CKRRFNVKLW KCFTECFNCL PVAALIDEKI LCMHGGLSPV LTNLDQIRNL 200
PRPTDVPDSG LLCDLLWSDP SREVKGWGMN DRGVSYTFGP DKVAEFLMQH 250
DMDLVCRAHQ VVEDGYEFFA ERQLVTIFSA PNYCGEFDNA GAMMSVDESL 300
MCSFQILKPT DRKPRFL 317
Length:317
Mass (Da):36,266
Last modified:July 1, 1997 - v1
Checksum:iC7613FE847CCDD36
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z93768 mRNA. Translation: CAB07803.1.
PIRiT03594.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z93768 mRNA. Translation: CAB07803.1 .
PIRi T03594.

3D structure databases

ProteinModelPortali O04856.
SMRi O04856. Positions 20-316.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi O04856.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Multiple genes encoding serine/threonine protein phosphatases and their differential expression in Nicotiana tabacum."
    Suh M., Cho H., Kim Y., Liu J., Lee H.
    Plant Mol. Biol. 36:315-322(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Xanthi.

Entry informationi

Entry nameiPP11_TOBAC
AccessioniPrimary (citable) accession number: O04856
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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