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O04856 (PP11_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1 isozyme 1

EC=3.1.3.16
Gene names
Name:NPP1
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 317317Serine/threonine-protein phosphatase PP1 isozyme 1
PRO_0000058811

Sites

Active site1361Proton donor By similarity
Metal binding751Iron By similarity
Metal binding771Iron By similarity
Metal binding1031Iron By similarity
Metal binding1031Manganese By similarity
Metal binding1351Manganese By similarity
Metal binding1841Manganese By similarity
Metal binding2591Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
O04856 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: C7613FE847CCDD36

FASTA31736,266
        10         20         30         40         50         60 
MAQNNEQQQQ GQGLIEAGVL DDIINRLLEF RNARTVRQVQ LSEAEIRSLC SASREIFLQQ 

        70         80         90        100        110        120 
PNLLDLKPPI KICGDIHGQY GDLLRLFEYG GFPPEANYLF LGDYVDRGKQ SLETICLLLA 

       130        140        150        160        170        180 
YKIKYPENFF LLRGNHECAS INRIYGFYDE CKRRFNVKLW KCFTECFNCL PVAALIDEKI 

       190        200        210        220        230        240 
LCMHGGLSPV LTNLDQIRNL PRPTDVPDSG LLCDLLWSDP SREVKGWGMN DRGVSYTFGP 

       250        260        270        280        290        300 
DKVAEFLMQH DMDLVCRAHQ VVEDGYEFFA ERQLVTIFSA PNYCGEFDNA GAMMSVDESL 

       310 
MCSFQILKPT DRKPRFL 

« Hide

References

[1]"Multiple genes encoding serine/threonine protein phosphatases and their differential expression in Nicotiana tabacum."
Suh M., Cho H., Kim Y., Liu J., Lee H.
Plant Mol. Biol. 36:315-322(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Xanthi.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z93768 mRNA. Translation: CAB07803.1.
PIRT03594.

3D structure databases

ProteinModelPortalO04856.
SMRO04856. Positions 20-316.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO04856.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP11_TOBAC
AccessionPrimary (citable) accession number: O04856
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families