Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Major pollen allergen Cyn d 1

Gene

CYND1

Organism
Cynodon dactylon (Bermuda grass) (Panicum dactylon)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Cyn d 1
Alternative name(s):
Allergen: Cyn d 1
Gene namesi
Name:CYND1
OrganismiCynodon dactylon (Bermuda grass) (Panicum dactylon)
Taxonomic identifieri28909 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladeChloridoideaeCynodonteaeEleusininaeCynodon

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei266. Cyn d 1.
267. Cyn d 1.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 246246Major pollen allergen Cyn d 1PRO_0000154569Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi9 – 91N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO04701.

Structurei

3D structure databases

ProteinModelPortaliO04701.
SMRiO04701. Positions 6-244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 145107Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini159 – 24082Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin B subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O04701-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AIGDKPGPNI TATYGSKWLE ARATFYGSNP RGAAPDDHGG ACGYKDVDKP
60 70 80 90 100
PFDGMTACGN EPIFKDGLGC RACYEIKCKE PVECSGEPVL VKITDKNYEH
110 120 130 140 150
IAAYHFDLSG KAFGAMAKKG QEDKLRKAGE LTLQFRRVKC KYPSGTKITF
160 170 180 190 200
HIEKGSNDHY LALLVKYAAG DGNIVAVDIK PRDSDEFIPM KSSWGAIWRI
210 220 230 240
DPKKPLKGPF SIRLTSEGGA HLVQDDVIPA NWKPDTVYTS KLQFGA
Length:246
Mass (Da):26,889
Last modified:July 1, 1997 - v1
Checksum:i43D8442DBA588322
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S83343 mRNA. Translation: AAB50734.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S83343 mRNA. Translation: AAB50734.2.

3D structure databases

ProteinModelPortaliO04701.
SMRiO04701. Positions 6-244.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei266. Cyn d 1.
267. Cyn d 1.0101.

Proteomic databases

PRIDEiO04701.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and expression in yeast Pichia pastoris of a biologically active form of Cyn d 1, the major allergen of Bermuda grass pollen."
    Smith P.M., Suphioglu C., Griffith I.J., Theriault K., Knox R.B., Singh M.B.
    J. Allergy Clin. Immunol. 98:331-343(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Tissue: Pollen.

Entry informationi

Entry nameiMPAC1_CYNDA
AccessioniPrimary (citable) accession number: O04701
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: July 1, 1997
Last modified: February 17, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.