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Protein

Probable inactive receptor kinase At1g27190

Gene

At1g27190

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei329ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi307 – 315ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inactive receptor kinase At1g27190
Gene namesi
Ordered Locus Names:At1g27190
ORF Names:T7N9.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G27190
TAIRilocus:2205834 AT1G27190

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000030518425 – 601Probable inactive receptor kinase At1g27190Add BLAST577

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi52N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei298PhosphothreonineBy similarity1
Modified residuei383PhosphoserineBy similarity1
Modified residuei399PhosphothreonineBy similarity1
Modified residuei476PhosphotyrosineBy similarity1
Modified residuei478PhosphoserineBy similarity1
Modified residuei479PhosphothreonineBy similarity1
Modified residuei483PhosphoserineBy similarity1
Modified residuei586PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO04567
PRIDEiO04567

PTM databases

iPTMnetiO04567

Expressioni

Gene expression databases

ExpressionAtlasiO04567 baseline and differential
GenevisibleiO04567 AT

Interactioni

Protein-protein interaction databases

BioGridi24843, 29 interactors
IntActiO04567, 6 interactors
STRINGi3702.AT1G27190.1

Structurei

Secondary structure

1601
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi27 – 37Combined sources11
Turni44 – 47Combined sources4
Helixi53 – 55Combined sources3
Beta strandi64 – 67Combined sources4
Beta strandi74 – 78Combined sources5
Helixi90 – 94Combined sources5
Beta strandi100 – 102Combined sources3
Beta strandi106 – 108Combined sources3
Helixi116 – 119Combined sources4
Beta strandi124 – 127Combined sources4
Helixi139 – 143Combined sources5
Beta strandi148 – 151Combined sources4
Beta strandi158 – 160Combined sources3
Helixi163 – 167Combined sources5
Beta strandi173 – 175Combined sources3
Beta strandi179 – 184Combined sources6
Helixi187 – 189Combined sources3
Helixi194 – 196Combined sources3
Beta strandi199 – 202Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6FG8X-ray1.25B1-214[»]
6G3WX-ray2.20B/D25-214[»]
ProteinModelPortaliO04567
SMRiO04567
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati73 – 95LRR 1Add BLAST23
Repeati97 – 119LRR 2Add BLAST23
Repeati122 – 144LRR 3Add BLAST23
Repeati146 – 169LRR 4Add BLAST24
Repeati170 – 192LRR 5Add BLAST23
Domaini301 – 586Protein kinasePROSITE-ProRule annotationAdd BLAST286

Domaini

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IIWA Eukaryota
COG0515 LUCA
HOGENOMiHOG000116554
InParanoidiO04567
OMAiPEFINCK
OrthoDBiEOG0936061P
PhylomeDBiO04567

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF13516 LRR_6, 2 hits
PF08263 LRRNT_2, 1 hit
PF07714 Pkinase_Tyr, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O04567-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKKIFITLLW LLFISSFLCS SSSAEDDVLC LQGLKNSLID PSSRLSSWSF
60 70 80 90 100
PNSSASSICK LTGVSCWNEK ENRIISLQLQ SMQLAGEIPE SLKLCRSLQS
110 120 130 140 150
LDLSGNDLSG SIPSQICSWL PYLVTLDLSG NKLGGSIPTQ IVECKFLNAL
160 170 180 190 200
ILSDNKLSGS IPSQLSRLDR LRRLSLAGND LSGTIPSELA RFGGDDFSGN
210 220 230 240 250
NGLCGKPLSR CGALNGRNLS IIIVAGVLGA VGSLCVGLVI FWWFFIREGS
260 270 280 290 300
RKKKGYGAGK SKDDSDWIGL LRSHKLVQVT LFQKPIVKIK LGDLMAATNN
310 320 330 340 350
FSSGNIDVSS RTGVSYKADL PDGSALAVKR LSACGFGEKQ FRSEMNKLGE
360 370 380 390 400
LRHPNLVPLL GYCVVEDERL LVYKHMVNGT LFSQLHNGGL CDAVLDWPTR
410 420 430 440 450
RAIGVGAAKG LAWLHHGCQP PYLHQFISSN VILLDDDFDA RITDYGLAKL
460 470 480 490 500
VGSRDSNDSS FNNGDLGELG YVAPEYSSTM VASLKGDVYG FGIVLLELVT
510 520 530 540 550
GQKPLSVING VEGFKGSLVD WVSQYLGTGR SKDAIDRSIC DKGHDEEILQ
560 570 580 590 600
FLKIACSCVV SRPKERPTMI QVYESLKNMA DKHGVSEHYD EFPLVFNKQE

A
Length:601
Mass (Da):65,424
Last modified:July 1, 1997 - v1
Checksum:i7A263A3076F5D8A9
GO
Isoform 2 (identifier: O04567-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-294: Missing.

Note: No experimental confirmation available.
Show »
Length:307
Mass (Da):33,613
Checksum:i0D19198433301DB9
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0282611 – 294Missing in isoform 2. 1 PublicationAdd BLAST294

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000348 Genomic DNA Translation: AAF79872.1
CP002684 Genomic DNA Translation: AEE30792.1
BT015801 mRNA Translation: AAU94364.1
AK228940 mRNA Translation: BAF00829.1
RefSeqiNP_174039.1, NM_102481.4 [O04567-1]
UniGeneiAt.16279

Genome annotation databases

EnsemblPlantsiAT1G27190.1; AT1G27190.1; AT1G27190 [O04567-1]
GeneIDi839608
GrameneiAT1G27190.1; AT1G27190.1; AT1G27190 [O04567-1]
KEGGiath:AT1G27190

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiY1719_ARATH
AccessioniPrimary (citable) accession number: O04567
Secondary accession number(s): Q0WPX0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: July 1, 1997
Last modified: May 23, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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