Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable inactive receptor kinase At1g27190

Gene

At1g27190

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei329 – 3291ATPPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi307 – 3159ATPPROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G27190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inactive receptor kinase At1g27190
Gene namesi
Ordered Locus Names:At1g27190
ORF Names:T7N9.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G27190.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei221 – 24121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • nucleus Source: TAIR
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 601577Probable inactive receptor kinase At1g27190PRO_0000305184Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi52 – 521N-linked (GlcNAc...)Sequence analysis
Modified residuei298 – 2981PhosphothreonineBy similarity
Modified residuei383 – 3831PhosphoserineBy similarity
Modified residuei399 – 3991PhosphothreonineBy similarity
Modified residuei459 – 4591PhosphoserineBy similarity
Modified residuei476 – 4761PhosphotyrosineBy similarity
Modified residuei478 – 4781PhosphoserineBy similarity
Modified residuei479 – 4791PhosphothreonineBy similarity
Modified residuei483 – 4831PhosphoserineBy similarity
Modified residuei586 – 5861PhosphoserineCombined sources

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO04567.
PRIDEiO04567.

PTM databases

iPTMnetiO04567.

Expressioni

Gene expression databases

ExpressionAtlasiO04567. baseline and differential.
GenevisibleiO04567. AT.

Interactioni

Protein-protein interaction databases

BioGridi24843. 29 interactions.
IntActiO04567. 6 interactions.
STRINGi3702.AT1G27190.1.

Structurei

3D structure databases

ProteinModelPortaliO04567.
SMRiO04567. Positions 23-259, 271-599.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati73 – 9523LRR 1Add
BLAST
Repeati97 – 11923LRR 2Add
BLAST
Repeati122 – 14423LRR 3Add
BLAST
Repeati146 – 16924LRR 4Add
BLAST
Repeati170 – 19223LRR 5Add
BLAST
Domaini301 – 586286Protein kinasePROSITE-ProRule annotationAdd
BLAST

Domaini

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 5 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IIWA. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116554.
InParanoidiO04567.
OMAiTQIVECK.
PhylomeDBiO04567.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13516. LRR_6. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O04567-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKKIFITLLW LLFISSFLCS SSSAEDDVLC LQGLKNSLID PSSRLSSWSF
60 70 80 90 100
PNSSASSICK LTGVSCWNEK ENRIISLQLQ SMQLAGEIPE SLKLCRSLQS
110 120 130 140 150
LDLSGNDLSG SIPSQICSWL PYLVTLDLSG NKLGGSIPTQ IVECKFLNAL
160 170 180 190 200
ILSDNKLSGS IPSQLSRLDR LRRLSLAGND LSGTIPSELA RFGGDDFSGN
210 220 230 240 250
NGLCGKPLSR CGALNGRNLS IIIVAGVLGA VGSLCVGLVI FWWFFIREGS
260 270 280 290 300
RKKKGYGAGK SKDDSDWIGL LRSHKLVQVT LFQKPIVKIK LGDLMAATNN
310 320 330 340 350
FSSGNIDVSS RTGVSYKADL PDGSALAVKR LSACGFGEKQ FRSEMNKLGE
360 370 380 390 400
LRHPNLVPLL GYCVVEDERL LVYKHMVNGT LFSQLHNGGL CDAVLDWPTR
410 420 430 440 450
RAIGVGAAKG LAWLHHGCQP PYLHQFISSN VILLDDDFDA RITDYGLAKL
460 470 480 490 500
VGSRDSNDSS FNNGDLGELG YVAPEYSSTM VASLKGDVYG FGIVLLELVT
510 520 530 540 550
GQKPLSVING VEGFKGSLVD WVSQYLGTGR SKDAIDRSIC DKGHDEEILQ
560 570 580 590 600
FLKIACSCVV SRPKERPTMI QVYESLKNMA DKHGVSEHYD EFPLVFNKQE

A
Length:601
Mass (Da):65,424
Last modified:July 1, 1997 - v1
Checksum:i7A263A3076F5D8A9
GO
Isoform 2 (identifier: O04567-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-294: Missing.

Note: No experimental confirmation available.
Show »
Length:307
Mass (Da):33,613
Checksum:i0D19198433301DB9
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 294294Missing in isoform 2. 1 PublicationVSP_028261Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000348 Genomic DNA. Translation: AAF79872.1.
CP002684 Genomic DNA. Translation: AEE30792.1.
BT015801 mRNA. Translation: AAU94364.1.
AK228940 mRNA. Translation: BAF00829.1.
RefSeqiNP_174039.1. NM_102481.3. [O04567-1]
UniGeneiAt.16279.

Genome annotation databases

EnsemblPlantsiAT1G27190.1; AT1G27190.1; AT1G27190. [O04567-1]
GeneIDi839608.
KEGGiath:AT1G27190.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000348 Genomic DNA. Translation: AAF79872.1.
CP002684 Genomic DNA. Translation: AEE30792.1.
BT015801 mRNA. Translation: AAU94364.1.
AK228940 mRNA. Translation: BAF00829.1.
RefSeqiNP_174039.1. NM_102481.3. [O04567-1]
UniGeneiAt.16279.

3D structure databases

ProteinModelPortaliO04567.
SMRiO04567. Positions 23-259, 271-599.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24843. 29 interactions.
IntActiO04567. 6 interactions.
STRINGi3702.AT1G27190.1.

PTM databases

iPTMnetiO04567.

Proteomic databases

PaxDbiO04567.
PRIDEiO04567.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G27190.1; AT1G27190.1; AT1G27190. [O04567-1]
GeneIDi839608.
KEGGiath:AT1G27190.

Organism-specific databases

TAIRiAT1G27190.

Phylogenomic databases

eggNOGiENOG410IIWA. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116554.
InParanoidiO04567.
OMAiTQIVECK.
PhylomeDBiO04567.

Enzyme and pathway databases

BioCyciARA:AT1G27190-MONOMER.

Miscellaneous databases

PROiO04567.

Gene expression databases

ExpressionAtlasiO04567. baseline and differential.
GenevisibleiO04567. AT.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13516. LRR_6. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Arabidopsis ORF clones."
    Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  4. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: cv. Columbia.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-586, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Root.

Entry informationi

Entry nameiY1719_ARATH
AccessioniPrimary (citable) accession number: O04567
Secondary accession number(s): Q0WPX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.