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Protein

Probable inactive receptor kinase At1g27190

Gene

At1g27190

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei329ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi307 – 315ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inactive receptor kinase At1g27190
Gene namesi
Ordered Locus Names:At1g27190
ORF Names:T7N9.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G27190.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • nucleus Source: TAIR
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000030518425 – 601Probable inactive receptor kinase At1g27190Add BLAST577

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi52N-linked (GlcNAc...)Sequence analysis1
Modified residuei298PhosphothreonineBy similarity1
Modified residuei383PhosphoserineBy similarity1
Modified residuei399PhosphothreonineBy similarity1
Modified residuei476PhosphotyrosineBy similarity1
Modified residuei478PhosphoserineBy similarity1
Modified residuei479PhosphothreonineBy similarity1
Modified residuei483PhosphoserineBy similarity1
Modified residuei586PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO04567.
PRIDEiO04567.

PTM databases

iPTMnetiO04567.

Expressioni

Gene expression databases

ExpressionAtlasiO04567. baseline and differential.
GenevisibleiO04567. AT.

Interactioni

Protein-protein interaction databases

BioGridi24843. 29 interactors.
IntActiO04567. 6 interactors.
STRINGi3702.AT1G27190.1.

Structurei

3D structure databases

ProteinModelPortaliO04567.
SMRiO04567.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati73 – 95LRR 1Add BLAST23
Repeati97 – 119LRR 2Add BLAST23
Repeati122 – 144LRR 3Add BLAST23
Repeati146 – 169LRR 4Add BLAST24
Repeati170 – 192LRR 5Add BLAST23
Domaini301 – 586Protein kinasePROSITE-ProRule annotationAdd BLAST286

Domaini

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 5 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IIWA. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116554.
InParanoidiO04567.
OMAiTQIVECK.
OrthoDBiEOG0936061P.
PhylomeDBiO04567.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13516. LRR_6. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O04567-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKKIFITLLW LLFISSFLCS SSSAEDDVLC LQGLKNSLID PSSRLSSWSF
60 70 80 90 100
PNSSASSICK LTGVSCWNEK ENRIISLQLQ SMQLAGEIPE SLKLCRSLQS
110 120 130 140 150
LDLSGNDLSG SIPSQICSWL PYLVTLDLSG NKLGGSIPTQ IVECKFLNAL
160 170 180 190 200
ILSDNKLSGS IPSQLSRLDR LRRLSLAGND LSGTIPSELA RFGGDDFSGN
210 220 230 240 250
NGLCGKPLSR CGALNGRNLS IIIVAGVLGA VGSLCVGLVI FWWFFIREGS
260 270 280 290 300
RKKKGYGAGK SKDDSDWIGL LRSHKLVQVT LFQKPIVKIK LGDLMAATNN
310 320 330 340 350
FSSGNIDVSS RTGVSYKADL PDGSALAVKR LSACGFGEKQ FRSEMNKLGE
360 370 380 390 400
LRHPNLVPLL GYCVVEDERL LVYKHMVNGT LFSQLHNGGL CDAVLDWPTR
410 420 430 440 450
RAIGVGAAKG LAWLHHGCQP PYLHQFISSN VILLDDDFDA RITDYGLAKL
460 470 480 490 500
VGSRDSNDSS FNNGDLGELG YVAPEYSSTM VASLKGDVYG FGIVLLELVT
510 520 530 540 550
GQKPLSVING VEGFKGSLVD WVSQYLGTGR SKDAIDRSIC DKGHDEEILQ
560 570 580 590 600
FLKIACSCVV SRPKERPTMI QVYESLKNMA DKHGVSEHYD EFPLVFNKQE

A
Length:601
Mass (Da):65,424
Last modified:July 1, 1997 - v1
Checksum:i7A263A3076F5D8A9
GO
Isoform 2 (identifier: O04567-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-294: Missing.

Note: No experimental confirmation available.
Show »
Length:307
Mass (Da):33,613
Checksum:i0D19198433301DB9
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0282611 – 294Missing in isoform 2. 1 PublicationAdd BLAST294

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000348 Genomic DNA. Translation: AAF79872.1.
CP002684 Genomic DNA. Translation: AEE30792.1.
BT015801 mRNA. Translation: AAU94364.1.
AK228940 mRNA. Translation: BAF00829.1.
RefSeqiNP_174039.1. NM_102481.4. [O04567-1]
UniGeneiAt.16279.

Genome annotation databases

EnsemblPlantsiAT1G27190.1; AT1G27190.1; AT1G27190. [O04567-1]
GeneIDi839608.
GrameneiAT1G27190.1; AT1G27190.1; AT1G27190.
KEGGiath:AT1G27190.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000348 Genomic DNA. Translation: AAF79872.1.
CP002684 Genomic DNA. Translation: AEE30792.1.
BT015801 mRNA. Translation: AAU94364.1.
AK228940 mRNA. Translation: BAF00829.1.
RefSeqiNP_174039.1. NM_102481.4. [O04567-1]
UniGeneiAt.16279.

3D structure databases

ProteinModelPortaliO04567.
SMRiO04567.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24843. 29 interactors.
IntActiO04567. 6 interactors.
STRINGi3702.AT1G27190.1.

PTM databases

iPTMnetiO04567.

Proteomic databases

PaxDbiO04567.
PRIDEiO04567.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G27190.1; AT1G27190.1; AT1G27190. [O04567-1]
GeneIDi839608.
GrameneiAT1G27190.1; AT1G27190.1; AT1G27190.
KEGGiath:AT1G27190.

Organism-specific databases

TAIRiAT1G27190.

Phylogenomic databases

eggNOGiENOG410IIWA. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116554.
InParanoidiO04567.
OMAiTQIVECK.
OrthoDBiEOG0936061P.
PhylomeDBiO04567.

Miscellaneous databases

PROiO04567.

Gene expression databases

ExpressionAtlasiO04567. baseline and differential.
GenevisibleiO04567. AT.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13516. LRR_6. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY1719_ARATH
AccessioniPrimary (citable) accession number: O04567
Secondary accession number(s): Q0WPX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.