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O04567 (Y1719_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inactive receptor kinase At1g27190
Gene names
Ordered Locus Names:At1g27190
ORF Names:T7N9.25
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length601 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Domain

The protein kinase domain is predicted to be catalytically inactive.

Post-translational modification

Phosphorylation level varies significantly during early response to general elicitors.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 5 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O04567-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O04567-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-294: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 601577Probable inactive receptor kinase At1g27190
PRO_0000305184

Regions

Transmembrane221 – 24121Helical; Potential
Repeat73 – 9523LRR 1
Repeat97 – 11923LRR 2
Repeat122 – 14423LRR 3
Repeat146 – 16924LRR 4
Repeat170 – 19223LRR 5
Domain301 – 586286Protein kinase
Nucleotide binding307 – 3159ATP By similarity

Sites

Binding site3291ATP By similarity

Amino acid modifications

Modified residue5861Phosphoserine Ref.5 Ref.6
Glycosylation521N-linked (GlcNAc...) Potential

Natural variations

Alternative sequence1 – 294294Missing in isoform 2.
VSP_028261

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 7A263A3076F5D8A9

FASTA60165,424
        10         20         30         40         50         60 
MKKIFITLLW LLFISSFLCS SSSAEDDVLC LQGLKNSLID PSSRLSSWSF PNSSASSICK 

        70         80         90        100        110        120 
LTGVSCWNEK ENRIISLQLQ SMQLAGEIPE SLKLCRSLQS LDLSGNDLSG SIPSQICSWL 

       130        140        150        160        170        180 
PYLVTLDLSG NKLGGSIPTQ IVECKFLNAL ILSDNKLSGS IPSQLSRLDR LRRLSLAGND 

       190        200        210        220        230        240 
LSGTIPSELA RFGGDDFSGN NGLCGKPLSR CGALNGRNLS IIIVAGVLGA VGSLCVGLVI 

       250        260        270        280        290        300 
FWWFFIREGS RKKKGYGAGK SKDDSDWIGL LRSHKLVQVT LFQKPIVKIK LGDLMAATNN 

       310        320        330        340        350        360 
FSSGNIDVSS RTGVSYKADL PDGSALAVKR LSACGFGEKQ FRSEMNKLGE LRHPNLVPLL 

       370        380        390        400        410        420 
GYCVVEDERL LVYKHMVNGT LFSQLHNGGL CDAVLDWPTR RAIGVGAAKG LAWLHHGCQP 

       430        440        450        460        470        480 
PYLHQFISSN VILLDDDFDA RITDYGLAKL VGSRDSNDSS FNNGDLGELG YVAPEYSSTM 

       490        500        510        520        530        540 
VASLKGDVYG FGIVLLELVT GQKPLSVING VEGFKGSLVD WVSQYLGTGR SKDAIDRSIC 

       550        560        570        580        590        600 
DKGHDEEILQ FLKIACSCVV SRPKERPTMI QVYESLKNMA DKHGVSEHYD EFPLVFNKQE 


A

« Hide

Isoform 2 [UniParc].

Checksum: 0D19198433301DB9
Show »

FASTA30733,613

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed: 11130712] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: cv. Columbia.
[5]"Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis."
Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M., Menke F.L.H.
Mol. Cell. Proteomics 6:1198-1214(2007) [PubMed: 17317660] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-586, MASS SPECTROMETRY.
Strain: cv. Columbia.
[6]"Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis."
de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E., Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C., Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C., Hirt H.
J. Proteome Res. 7:2458-2470(2008) [PubMed: 18433157] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-586, MASS SPECTROMETRY.
Tissue: Root.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC000348 Genomic DNA. Translation: AAF79872.1.
CP002684 Genomic DNA. Translation: AEE30792.1.
BT015801 mRNA. Translation: AAU94364.1.
AK228940 mRNA. Translation: BAF00829.1.
IPIIPI00523297.
IPI00867960.
RefSeqNP_174039.1. NM_102481.3.
UniGeneAt.16279.

3D structure databases

ProteinModelPortalO04567.
SMRO04567. Positions 22-222, 291-581.
ModBaseSearch...

Protein-protein interaction databases

IntActO04567. 6 interactions.
STRINGO04567.

Proteomic databases

PRIDEO04567.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G27190.1; AT1G27190.1; AT1G27190.
GeneID839608.
GenomeReviewsGene locus AT1G27190 in contig CT485782_GR.
KEGGath:AT1G27190.
NMPDRfig|3702.1.peg.3042.

Organism-specific databases

GeneFarm2512. 54.
TAIRAt1g27190.

Phylogenomic databases

eggNOGCOG0515.
GeneTreeEPGT00070000028064.
HOGENOMHBG755340.
InParanoidO04567.
OMASIPSQIC.
PhylomeDBO04567.
ProtClustDBCLSN2912786.

Gene expression databases

GenevestigatorO04567.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_cat_dom.
IPR001245. Ser-Thr/Tyr_kinase.
[Graphical view]
PfamPF00560. LRR_1. 3 hits.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. False negative.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY1719_ARATH
AccessionPrimary (citable) accession number: O04567
Secondary accession number(s): Q0WPX0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: July 1, 1997
Last modified: December 14, 2011
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents