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O04533

- LRK52_ARATH

UniProt

O04533 - LRK52_ARATH

Protein

Putative L-type lectin-domain containing receptor kinase V.2

Gene

LECRK52

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 113 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei363 – 3631ATPPROSITE-ProRule annotation
    Active sitei459 – 4591Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi340 – 3489ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. carbohydrate binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Lectin, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G70130-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative L-type lectin-domain containing receptor kinase V.2 (EC:2.7.11.1)
    Short name:
    Arabidopsis thaliana lectin-receptor kinase b1
    Short name:
    AthlecRK-b1
    Short name:
    LecRK-V.2
    Gene namesi
    Name:LECRK52
    Synonyms:LECRKB1
    Ordered Locus Names:At1g70130
    ORF Names:F20P5.15
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G70130.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 656633Putative L-type lectin-domain containing receptor kinase V.2PRO_0000403090Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi78 – 781N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi124 – 1241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi159 – 1591N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi190 – 1901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi257 – 2571N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiO04533.

    Expressioni

    Gene expression databases

    GenevestigatoriO04533.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT1G70130.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO04533.
    SMRiO04533. Positions 41-249, 302-601.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini24 – 276253ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini298 – 656359CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei277 – 29721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini334 – 615282Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni29 – 248220Legume-lectin likeAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
    In the N-terminal section; belongs to the leguminous lectin family.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000116555.
    InParanoidiO04533.
    OMAiYMASISQ.
    PhylomeDBiO04533.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O04533-1 [UniParc]FASTAAdd to Basket

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    MSLLLKMLLF SLFFFYMASI SQCSDPTGGQ FSFNGYLYTD GVADLNPDGL    50
    FKLITSKTQG GAGQVLYQFP LQFKNSPNGT VSSFSTTFVF AIVAVRKTIA 100
    GCGLSFNISP TKGLNSVPNI DHSNHSVSVG FHTAKSDKPD GEDVNLVGIN 150
    IDSSKMDRNC SAGYYKDDGR LVNLDIASGK PIQVWIEYNN STKQLDVTMH 200
    SIKISKPKIP LLSMRKDLSP YLHEYMYIGF TSVGSPTSSH YILGWSFNNK 250
    GAVSDINLSR LPKVPDEDQE RSLSSKILAI SLSISGVTLV IVLILGVMLF 300
    LKRKKFLEVI EDWEVQFGPH KFTYKDLFIA TKGFKNSEVL GKGGFGKVFK 350
    GILPLSSIPI AVKKISHDSR QGMREFLAEI ATIGRLRHPD LVRLLGYCRR 400
    KGELYLVYDF MPKGSLDKFL YNQPNQILDW SQRFNIIKDV ASGLCYLHQQ 450
    WVQVIIHRDI KPANILLDEN MNAKLGDFGL AKLCDHGIDS QTSNVAGTFG 500
    YISPELSRTG KSSTSSDVFA FGVFMLEITC GRRPIGPRGS PSEMVLTDWV 550
    LDCWDSGDIL QVVDEKLGHR YLAEQVTLVL KLGLLCSHPV AATRPSMSSV 600
    IQFLDGVATL PHNLLDLVNS RIINEGFDTL GVTTESMEAS SNVSLVMTES 650
    FLSSGR 656
    Length:656
    Mass (Da):72,455
    Last modified:July 1, 1997 - v1
    Checksum:iF438795FA65C9A12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC002062 Genomic DNA. Translation: AAB61102.1.
    CP002684 Genomic DNA. Translation: AEE35023.1.
    PIRiA96724.
    RefSeqiNP_177170.1. NM_105681.1.
    UniGeneiAt.66126.

    Genome annotation databases

    EnsemblPlantsiAT1G70130.1; AT1G70130.1; AT1G70130.
    GeneIDi843349.
    KEGGiath:AT1G70130.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC002062 Genomic DNA. Translation: AAB61102.1 .
    CP002684 Genomic DNA. Translation: AEE35023.1 .
    PIRi A96724.
    RefSeqi NP_177170.1. NM_105681.1.
    UniGenei At.66126.

    3D structure databases

    ProteinModelPortali O04533.
    SMRi O04533. Positions 41-249, 302-601.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT1G70130.1-P.

    Proteomic databases

    PRIDEi O04533.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G70130.1 ; AT1G70130.1 ; AT1G70130 .
    GeneIDi 843349.
    KEGGi ath:AT1G70130.

    Organism-specific databases

    GeneFarmi 2645. 4.
    TAIRi AT1G70130.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000116555.
    InParanoidi O04533.
    OMAi YMASISQ.
    PhylomeDBi O04533.

    Enzyme and pathway databases

    BioCyci ARA:AT1G70130-MONOMER.

    Gene expression databases

    Genevestigatori O04533.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
      Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
      Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.
    4. Cited for: GENE FAMILY.
    5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
      Bouwmeester K., Govers F.
      J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiLRK52_ARATH
    AccessioniPrimary (citable) accession number: O04533
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2011
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 113 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3