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O04533 (LRK52_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative L-type lectin-domain containing receptor kinase V.2

Short name=Arabidopsis thaliana lectin-receptor kinase b1
Short name=AthlecRK-b1
Short name=LecRK-V.2
EC=2.7.11.1
Gene names
Name:LECRK52
Synonyms:LECRKB1
Ordered Locus Names:At1g70130
ORF Names:F20P5.15
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length656 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

In the N-terminal section; belongs to the leguminous lectin family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 656633Putative L-type lectin-domain containing receptor kinase V.2
PRO_0000403090

Regions

Topological domain24 – 276253Extracellular Potential
Transmembrane277 – 29721Helical; Potential
Topological domain298 – 656359Cytoplasmic Potential
Domain334 – 615282Protein kinase
Nucleotide binding340 – 3489ATP By similarity
Region29 – 248220Legume-lectin like

Sites

Active site4591Proton acceptor By similarity
Binding site3631ATP By similarity

Amino acid modifications

Glycosylation781N-linked (GlcNAc...) Potential
Glycosylation1241N-linked (GlcNAc...) Potential
Glycosylation1591N-linked (GlcNAc...) Potential
Glycosylation1901N-linked (GlcNAc...) Potential
Glycosylation2571N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O04533 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: F438795FA65C9A12

FASTA65672,455
        10         20         30         40         50         60 
MSLLLKMLLF SLFFFYMASI SQCSDPTGGQ FSFNGYLYTD GVADLNPDGL FKLITSKTQG 

        70         80         90        100        110        120 
GAGQVLYQFP LQFKNSPNGT VSSFSTTFVF AIVAVRKTIA GCGLSFNISP TKGLNSVPNI 

       130        140        150        160        170        180 
DHSNHSVSVG FHTAKSDKPD GEDVNLVGIN IDSSKMDRNC SAGYYKDDGR LVNLDIASGK 

       190        200        210        220        230        240 
PIQVWIEYNN STKQLDVTMH SIKISKPKIP LLSMRKDLSP YLHEYMYIGF TSVGSPTSSH 

       250        260        270        280        290        300 
YILGWSFNNK GAVSDINLSR LPKVPDEDQE RSLSSKILAI SLSISGVTLV IVLILGVMLF 

       310        320        330        340        350        360 
LKRKKFLEVI EDWEVQFGPH KFTYKDLFIA TKGFKNSEVL GKGGFGKVFK GILPLSSIPI 

       370        380        390        400        410        420 
AVKKISHDSR QGMREFLAEI ATIGRLRHPD LVRLLGYCRR KGELYLVYDF MPKGSLDKFL 

       430        440        450        460        470        480 
YNQPNQILDW SQRFNIIKDV ASGLCYLHQQ WVQVIIHRDI KPANILLDEN MNAKLGDFGL 

       490        500        510        520        530        540 
AKLCDHGIDS QTSNVAGTFG YISPELSRTG KSSTSSDVFA FGVFMLEITC GRRPIGPRGS 

       550        560        570        580        590        600 
PSEMVLTDWV LDCWDSGDIL QVVDEKLGHR YLAEQVTLVL KLGLLCSHPV AATRPSMSSV 

       610        620        630        640        650 
IQFLDGVATL PHNLLDLVNS RIINEGFDTL GVTTESMEAS SNVSLVMTES FLSSGR 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
[4]"Lectin receptor kinases in plants."
Barre A., Herve C., Lescure B., Rouge P.
Crit. Rev. Plant Sci. 21:379-399(2002)
Cited for: GENE FAMILY.
[5]"Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
Bouwmeester K., Govers F.
J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC002062 Genomic DNA. Translation: AAB61102.1.
CP002684 Genomic DNA. Translation: AEE35023.1.
PIRA96724.
RefSeqNP_177170.1. NM_105681.1.
UniGeneAt.66126.

3D structure databases

ProteinModelPortalO04533.
SMRO04533. Positions 41-249, 321-606.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G70130.1-P.

Proteomic databases

PRIDEO04533.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G70130.1; AT1G70130.1; AT1G70130.
GeneID843349.
KEGGath:AT1G70130.

Organism-specific databases

GeneFarm2645. 4.
TAIRAT1G70130.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116555.
InParanoidO04533.
OMAYMASISQ.
PhylomeDBO04533.
ProtClustDBCLSN2682759.

Enzyme and pathway databases

BioCycARA:AT1G70130-MONOMER.

Gene expression databases

GenevestigatorO04533.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLRK52_ARATH
AccessionPrimary (citable) accession number: O04533
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: July 1, 1997
Last modified: March 19, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names