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O04533

- LRK52_ARATH

UniProt

O04533 - LRK52_ARATH

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Protein

Putative L-type lectin-domain containing receptor kinase V.2

Gene

LECRK52

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei363 – 3631ATPPROSITE-ProRule annotation
Active sitei459 – 4591Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi340 – 3489ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbohydrate binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G70130-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L-type lectin-domain containing receptor kinase V.2 (EC:2.7.11.1)
Short name:
Arabidopsis thaliana lectin-receptor kinase b1
Short name:
AthlecRK-b1
Short name:
LecRK-V.2
Gene namesi
Name:LECRK52
Synonyms:LECRKB1
Ordered Locus Names:At1g70130
ORF Names:F20P5.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G70130.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini24 – 276253ExtracellularSequence AnalysisAdd
BLAST
Transmembranei277 – 29721HelicalSequence AnalysisAdd
BLAST
Topological domaini298 – 656359CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 656633Putative L-type lectin-domain containing receptor kinase V.2PRO_0000403090Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi78 – 781N-linked (GlcNAc...)Sequence Analysis
Glycosylationi124 – 1241N-linked (GlcNAc...)Sequence Analysis
Glycosylationi159 – 1591N-linked (GlcNAc...)Sequence Analysis
Glycosylationi190 – 1901N-linked (GlcNAc...)Sequence Analysis
Glycosylationi257 – 2571N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO04533.

Expressioni

Gene expression databases

GenevestigatoriO04533.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G70130.1-P.

Structurei

3D structure databases

ProteinModelPortaliO04533.
SMRiO04533. Positions 41-249, 302-601.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini334 – 615282Protein kinasePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni29 – 248220Legume-lectin likeAdd
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000116555.
InParanoidiO04533.
OMAiYMASISQ.
PhylomeDBiO04533.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O04533-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLLLKMLLF SLFFFYMASI SQCSDPTGGQ FSFNGYLYTD GVADLNPDGL
60 70 80 90 100
FKLITSKTQG GAGQVLYQFP LQFKNSPNGT VSSFSTTFVF AIVAVRKTIA
110 120 130 140 150
GCGLSFNISP TKGLNSVPNI DHSNHSVSVG FHTAKSDKPD GEDVNLVGIN
160 170 180 190 200
IDSSKMDRNC SAGYYKDDGR LVNLDIASGK PIQVWIEYNN STKQLDVTMH
210 220 230 240 250
SIKISKPKIP LLSMRKDLSP YLHEYMYIGF TSVGSPTSSH YILGWSFNNK
260 270 280 290 300
GAVSDINLSR LPKVPDEDQE RSLSSKILAI SLSISGVTLV IVLILGVMLF
310 320 330 340 350
LKRKKFLEVI EDWEVQFGPH KFTYKDLFIA TKGFKNSEVL GKGGFGKVFK
360 370 380 390 400
GILPLSSIPI AVKKISHDSR QGMREFLAEI ATIGRLRHPD LVRLLGYCRR
410 420 430 440 450
KGELYLVYDF MPKGSLDKFL YNQPNQILDW SQRFNIIKDV ASGLCYLHQQ
460 470 480 490 500
WVQVIIHRDI KPANILLDEN MNAKLGDFGL AKLCDHGIDS QTSNVAGTFG
510 520 530 540 550
YISPELSRTG KSSTSSDVFA FGVFMLEITC GRRPIGPRGS PSEMVLTDWV
560 570 580 590 600
LDCWDSGDIL QVVDEKLGHR YLAEQVTLVL KLGLLCSHPV AATRPSMSSV
610 620 630 640 650
IQFLDGVATL PHNLLDLVNS RIINEGFDTL GVTTESMEAS SNVSLVMTES

FLSSGR
Length:656
Mass (Da):72,455
Last modified:July 1, 1997 - v1
Checksum:iF438795FA65C9A12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002062 Genomic DNA. Translation: AAB61102.1.
CP002684 Genomic DNA. Translation: AEE35023.1.
PIRiA96724.
RefSeqiNP_177170.1. NM_105681.1.
UniGeneiAt.66126.

Genome annotation databases

EnsemblPlantsiAT1G70130.1; AT1G70130.1; AT1G70130.
GeneIDi843349.
KEGGiath:AT1G70130.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002062 Genomic DNA. Translation: AAB61102.1 .
CP002684 Genomic DNA. Translation: AEE35023.1 .
PIRi A96724.
RefSeqi NP_177170.1. NM_105681.1.
UniGenei At.66126.

3D structure databases

ProteinModelPortali O04533.
SMRi O04533. Positions 41-249, 302-601.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT1G70130.1-P.

Proteomic databases

PRIDEi O04533.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G70130.1 ; AT1G70130.1 ; AT1G70130 .
GeneIDi 843349.
KEGGi ath:AT1G70130.

Organism-specific databases

GeneFarmi 2645. 4.
TAIRi AT1G70130.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000116555.
InParanoidi O04533.
OMAi YMASISQ.
PhylomeDBi O04533.

Enzyme and pathway databases

BioCyci ARA:AT1G70130-MONOMER.

Gene expression databases

Genevestigatori O04533.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
    Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
    Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  4. Cited for: GENE FAMILY.
  5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
    Bouwmeester K., Govers F.
    J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiLRK52_ARATH
AccessioniPrimary (citable) accession number: O04533
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: July 1, 1997
Last modified: October 29, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3