Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O04486

- RAA2A_ARATH

UniProt

O04486 - RAA2A_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ras-related protein RABA2a

Gene

RABA2A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

Intracellular vesicle trafficking and protein transport.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPBy similarity
Nucleotide bindingi67 – 715GTPBy similarity
Nucleotide bindingi125 – 1284GTPBy similarity
Nucleotide bindingi155 – 1562GTPBy similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW

GO - Biological processi

  1. cytokinesis by cell plate formation Source: TAIR
  2. protein transport Source: UniProtKB-KW
  3. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABA2a
Short name:
AtRABA2a
Alternative name(s):
Ras-related protein Rab11C
Short name:
AtRab11C
Gene namesi
Name:RABA2A
Synonyms:RAB11C
Ordered Locus Names:At1g09630
ORF Names:F21M12.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G09630.

Subcellular locationi

Endosome membrane 1 Publication. Golgi apparatustrans-Golgi network membrane 1 Publication; Lipid-anchor 1 Publication
Note: During cytokinesis located to the growing margins of the cell plate.

GO - Cellular componenti

  1. cell plate Source: TAIR
  2. cytosol Source: TAIR
  3. endosome Source: TAIR
  4. Golgi apparatus Source: UniProtKB-KW
  5. plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Endosome, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 214213Ras-related protein RABA2aPRO_0000121165Add
BLAST
Propeptidei215 – 2173Removed in mature formSequence AnalysisPRO_0000370754

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi213 – 2131S-palmitoyl cysteineBy similarity
Modified residuei214 – 2141Cysteine methyl esterSequence Analysis
Lipidationi214 – 2141S-geranylgeranyl cysteineBy similarity

Keywords - PTMi

Lipoprotein, Methylation, Palmitate, Prenylation

Proteomic databases

PaxDbiO04486.
PRIDEiO04486.

Expressioni

Tissue specificityi

Expressed in root tips.1 Publication

Gene expression databases

GenevestigatoriO04486.

Interactioni

Protein-protein interaction databases

BioGridi22731. 3 interactions.
IntActiO04486. 4 interactions.
MINTiMINT-7712599.
STRINGi3702.AT1G09630.1-P.

Structurei

3D structure databases

ProteinModelPortaliO04486.
SMRiO04486. Positions 9-176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi41 – 499Effector regionBy similarity

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiCOG1100.
HOGENOMiHOG000233968.
InParanoidiO04486.
KOiK07904.
OMAiAKKPCCS.
PhylomeDBiO04486.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O04486-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARRPDEEYD YLFKVVLIGD SGVGKSNLLS RFTRNEFCLE SKSTIGVEFA
60 70 80 90 100
TRTLQVEGRT VKAQIWDTAG QERYRAITSA YYRGALGALL VYDVTKPTTF
110 120 130 140 150
ENVSRWLKEL RDHADSNIVI MLIGNKTDLK HLRAVATEDA QSYAEKEGLS
160 170 180 190 200
FIETSALEAL NVEKAFQTIL SEVYRIISKK SISSDQTTAN ANIKEGQTID
210
VAATSESNAK KPCCSSS
Length:217
Mass (Da):24,108
Last modified:July 1, 1997 - v1
Checksum:iD8DBFD3192FD92C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U74669 mRNA. Translation: AAB61994.1.
AC000132 Genomic DNA. Translation: AAB60720.1.
CP002684 Genomic DNA. Translation: AEE28471.1.
AY045620 mRNA. Translation: AAK73978.1.
AY133657 mRNA. Translation: AAM91487.1.
AY085684 mRNA. Translation: AAM62903.1.
PIRiA86230.
RefSeqiNP_172434.1. NM_100835.2.
UniGeneiAt.20265.

Genome annotation databases

EnsemblPlantsiAT1G09630.1; AT1G09630.1; AT1G09630.
GeneIDi837490.
KEGGiath:AT1G09630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U74669 mRNA. Translation: AAB61994.1 .
AC000132 Genomic DNA. Translation: AAB60720.1 .
CP002684 Genomic DNA. Translation: AEE28471.1 .
AY045620 mRNA. Translation: AAK73978.1 .
AY133657 mRNA. Translation: AAM91487.1 .
AY085684 mRNA. Translation: AAM62903.1 .
PIRi A86230.
RefSeqi NP_172434.1. NM_100835.2.
UniGenei At.20265.

3D structure databases

ProteinModelPortali O04486.
SMRi O04486. Positions 9-176.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 22731. 3 interactions.
IntActi O04486. 4 interactions.
MINTi MINT-7712599.
STRINGi 3702.AT1G09630.1-P.

Proteomic databases

PaxDbi O04486.
PRIDEi O04486.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G09630.1 ; AT1G09630.1 ; AT1G09630 .
GeneIDi 837490.
KEGGi ath:AT1G09630.

Organism-specific databases

TAIRi AT1G09630.

Phylogenomic databases

eggNOGi COG1100.
HOGENOMi HOG000233968.
InParanoidi O04486.
KOi K07904.
OMAi AKKPCCS.
PhylomeDBi O04486.

Gene expression databases

Genevestigatori O04486.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view ]
Pfami PF00071. Ras. 1 hit.
[Graphical view ]
PRINTSi PR00449. RASTRNSFRMNG.
SMARTi SM00175. RAB. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00231. small_GTP. 1 hit.
PROSITEi PS51419. RAB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Bischoff F., Palme K.
    Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. "Analysis of the small GTPase gene superfamily of Arabidopsis."
    Vernoud V., Horton A.C., Yang Z., Nielsen E.
    Plant Physiol. 131:1191-1208(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  7. "Rab-A2 and Rab-A3 GTPases define a trans-Golgi endosomal membrane domain in Arabidopsis that contributes substantially to the cell plate."
    Chow C.M., Neto H., Foucart C., Moore I.
    Plant Cell 20:101-123(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY.

Entry informationi

Entry nameiRAA2A_ARATH
AccessioniPrimary (citable) accession number: O04486
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: October 29, 2014
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3