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O04486 (RAA2A_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 115. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ras-related protein RABA2a

Short name=AtRABA2a
Alternative name(s):
Ras-related protein Rab11C
Short name=AtRab11C
Gene names
Name:RABA2A
Synonyms:RAB11C
Ordered Locus Names:At1g09630
ORF Names:F21M12.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length217 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Intracellular vesicle trafficking and protein transport By similarity.

Subcellular location

Endosome membrane. Golgi apparatustrans-Golgi network membrane; Lipid-anchor Probable. Note: During cytokinesis located to the growing margins of the cell plate. Ref.7

Tissue specificity

Expressed in root tips. Ref.7

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 214213Ras-related protein RABA2a
PRO_0000121165
Propeptide215 – 2173Removed in mature form Potential
PRO_0000370754

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding67 – 715GTP By similarity
Nucleotide binding125 – 1284GTP By similarity
Nucleotide binding155 – 1562GTP By similarity
Motif41 – 499Effector region By similarity

Amino acid modifications

Modified residue2141Cysteine methyl ester Potential
Lipidation2131S-palmitoyl cysteine By similarity
Lipidation2141S-geranylgeranyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
O04486 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: D8DBFD3192FD92C8

FASTA21724,108
        10         20         30         40         50         60 
MARRPDEEYD YLFKVVLIGD SGVGKSNLLS RFTRNEFCLE SKSTIGVEFA TRTLQVEGRT 

        70         80         90        100        110        120 
VKAQIWDTAG QERYRAITSA YYRGALGALL VYDVTKPTTF ENVSRWLKEL RDHADSNIVI 

       130        140        150        160        170        180 
MLIGNKTDLK HLRAVATEDA QSYAEKEGLS FIETSALEAL NVEKAFQTIL SEVYRIISKK 

       190        200        210 
SISSDQTTAN ANIKEGQTID VAATSESNAK KPCCSSS 

« Hide

References

« Hide 'large scale' references
[1]Bischoff F., Palme K.
Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]"Analysis of the small GTPase gene superfamily of Arabidopsis."
Vernoud V., Horton A.C., Yang Z., Nielsen E.
Plant Physiol. 131:1191-1208(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[7]"Rab-A2 and Rab-A3 GTPases define a trans-Golgi endosomal membrane domain in Arabidopsis that contributes substantially to the cell plate."
Chow C.M., Neto H., Foucart C., Moore I.
Plant Cell 20:101-123(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U74669 mRNA. Translation: AAB61994.1.
AC000132 Genomic DNA. Translation: AAB60720.1.
CP002684 Genomic DNA. Translation: AEE28471.1.
AY045620 mRNA. Translation: AAK73978.1.
AY133657 mRNA. Translation: AAM91487.1.
AY085684 mRNA. Translation: AAM62903.1.
PIRA86230.
RefSeqNP_172434.1. NM_100835.2.
UniGeneAt.20265.

3D structure databases

ProteinModelPortalO04486.
SMRO04486. Positions 9-176.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid22731. 3 interactions.
IntActO04486. 4 interactions.
MINTMINT-7712599.
STRING3702.AT1G09630.1-P.

Proteomic databases

PaxDbO04486.
PRIDEO04486.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G09630.1; AT1G09630.1; AT1G09630.
GeneID837490.
KEGGath:AT1G09630.

Organism-specific databases

TAIRAT1G09630.

Phylogenomic databases

eggNOGCOG1100.
HOGENOMHOG000233968.
InParanoidO04486.
KOK07904.
OMAAKKPCCS.
PhylomeDBO04486.

Gene expression databases

GenevestigatorO04486.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SMARTSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRAA2A_ARATH
AccessionPrimary (citable) accession number: O04486
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: May 14, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names