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O04478

- GUN7_ARATH

UniProt

O04478 - GUN7_ARATH

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Protein
Endoglucanase 7
Gene
KOR2, At1g65610, F5I14.14
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei517 – 5171 By similarity
Active sitei565 – 5651 By similarity
Active sitei574 – 5741 By similarity

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciARA:AT1G65610-MONOMER.

Protein family/group databases

CAZyiGH9. Glycoside Hydrolase Family 9.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 7 (EC:3.2.1.4)
Alternative name(s):
Endo-1,4-beta glucanase 7
Gene namesi
Name:KOR2
Ordered Locus Names:At1g65610
ORF Names:F5I14.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G65610.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 7979Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei80 – 10021Helical; Signal-anchor for type II membrane protein; Reviewed prediction
Add
BLAST
Topological domaini101 – 623523Extracellular Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 623623Endoglucanase 7
PRO_0000249260Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi116 – 1161N-linked (GlcNAc...) Reviewed prediction
Glycosylationi221 – 2211N-linked (GlcNAc...) Reviewed prediction
Glycosylationi328 – 3281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi349 – 3491N-linked (GlcNAc...) Reviewed prediction
Glycosylationi412 – 4121N-linked (GlcNAc...) Reviewed prediction
Glycosylationi429 – 4291N-linked (GlcNAc...) Reviewed prediction
Glycosylationi464 – 4641N-linked (GlcNAc...) Reviewed prediction
Glycosylationi548 – 5481N-linked (GlcNAc...) Reviewed prediction
Glycosylationi571 – 5711N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO04478.
PRIDEiO04478.

Expressioni

Tissue specificityi

Expressed in basal region of leaf blade and proximal parts of leaf and floral organ.1 Publication

Developmental stagei

Early expressed in the development of root hairs within the root differentiation zone. Expressed late in the development of leaf trichomes when the stalks and branches are expanded.1 Publication

Gene expression databases

GenevestigatoriO04478.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G65610.1-P.

Structurei

3D structure databases

ProteinModelPortaliO04478.
SMRiO04478. Positions 113-616.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG307789.
HOGENOMiHOG000021033.
InParanoidiO04478.
OMAiPYIEPFY.
PhylomeDBiO04478.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamiPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O04478-1 [UniParc]FASTAAdd to Basket

« Hide

MHPGNVWGGS LDAVDSDRIA AEEEERLRNT TEWDRGAIHS QRSELDETQQ    50
GWLLAPQDNW RKKKKKYVNL GCVSVSRTVF LWTVGSIAVL FLVVALPIII 100
VKSLPRHKSA PPPPDNYTLA LHKALQFFDA QKSGKLPKKN KVSWRGDSGT 150
KDGLPDVVGG LVGGYYDGGS NVKFHFPMAF SMTMLSWSLI EYSHKYKAID 200
EYDHMRDVLK WGTDYLLLTF NNSATRLDHI YTQVGGGLRD SESPDDIYCW 250
QKPEDMSYDR PVLSSTSAAD LGAEVSAALA AASIVFTDKP DYAKKLKKGA 300
ETLYPFFRSK SRRKRYSDGQ PTAQAFYNST SMFDEFMWAG AWLYYATGNK 350
TYIQFATTPS VPQTAKAFAN RPELMVPSWN NKLPGAMLLM TRYRLFLNPG 400
FPYENMLNRY HNATGITMCA YLKQYNVFNR TSGGLMQLNL GKPRPLEYVA 450
HASFLASLFA DYLNSTGVPG WYCGPTFVEN HVLKDFAQSQ IDYILGDNPL 500
KMSYVVGFGK KFPRRVHHRG ATIPNDKKRR SCREGLKYRD TKNPNPNNIT 550
GAMVGGPNKF DEFHDLRNNY NASEPTLSGN AGLVAALVSL TSSGGQQIDK 600
NTMFNSVPPL YSPTPPPPKA WKP 623
Length:623
Mass (Da):69,836
Last modified:July 1, 1997 - v1
Checksum:i8186D6B5497D1FD4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC001229 Genomic DNA. Translation: AAB60922.1.
CP002684 Genomic DNA. Translation: AEE34400.1.
AK229402 mRNA. Translation: BAF01264.1.
PIRiB96681.
RefSeqiNP_176738.1. NM_105234.2.
UniGeneiAt.35864.

Genome annotation databases

EnsemblPlantsiAT1G65610.1; AT1G65610.1; AT1G65610.
GeneIDi842872.
KEGGiath:AT1G65610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC001229 Genomic DNA. Translation: AAB60922.1 .
CP002684 Genomic DNA. Translation: AEE34400.1 .
AK229402 mRNA. Translation: BAF01264.1 .
PIRi B96681.
RefSeqi NP_176738.1. NM_105234.2.
UniGenei At.35864.

3D structure databases

ProteinModelPortali O04478.
SMRi O04478. Positions 113-616.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT1G65610.1-P.

Protein family/group databases

CAZyi GH9. Glycoside Hydrolase Family 9.

Proteomic databases

PaxDbi O04478.
PRIDEi O04478.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G65610.1 ; AT1G65610.1 ; AT1G65610 .
GeneIDi 842872.
KEGGi ath:AT1G65610.

Organism-specific databases

TAIRi AT1G65610.

Phylogenomic databases

eggNOGi NOG307789.
HOGENOMi HOG000021033.
InParanoidi O04478.
OMAi PYIEPFY.
PhylomeDBi O04478.

Enzyme and pathway databases

BioCyci ARA:AT1G65610-MONOMER.

Gene expression databases

Genevestigatori O04478.

Family and domain databases

Gene3Di 1.50.10.10. 1 hit.
InterProi IPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view ]
Pfami PF00759. Glyco_hydro_9. 1 hit.
[Graphical view ]
SUPFAMi SSF48208. SSF48208. 1 hit.
PROSITEi PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Two Arabidopsis thaliana genes, KOR2 and KOR3, which encode membrane-anchored endo-1,4-beta-D-glucanases, are differentially expressed in developing leaf trichomes and their support cells."
    Moelhoej M., Joergensen B., Ulvskov P., Borkhardt B.
    Plant Mol. Biol. 46:263-275(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
  5. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
    Libertini E., Li Y., McQueen-Mason S.J.
    J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiGUN7_ARATH
AccessioniPrimary (citable) accession number: O04478
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: July 1, 1997
Last modified: May 14, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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