O04437 (GSTZ_WHEAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutathione S-transferase
EC=2.5.1.18

Alternative name(s):
GST class-zeta

Gene names

Name:

GSTZ1

Organism

Triticum aestivum (Wheat)

Taxonomic identifier

4565 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has a glutathione transferase activity with ethacrynic acid and nitrophenyl acetate. Has low glutathione peroxidase activity with cumene hydroperoxide.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GST superfamily. Zeta family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Gene Ontology (GO)
Biological_process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Glutathione S-transferase		PRO_0000186034
Regions
	Domain	4 – 81	78	GST N-terminal
	Domain	86 – 211	126	GST C-terminal

Sequences

	Sequence		Length	Mass (Da)
	O04437 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: CA235D0AC66F0A54	FASTA	213	23,752
	10 20 30 40 50 60 MATAKPILYG AWISSCSHRV RIALNLKGVD YEYKAVNPRT DPDYEKINPI KYIPALVDGD 70 80 90 100 110 120 FVLSDSLAIM LYLEDKYPQH PLVPKDIKTK GLDLQIANIV CSSIQPLQGY GVIGLHEGRL 130 140 150 160 170 180 SPDESLEVVQ RYIDKGFRAI EKLLDGCDSK YCVGDEVHLG DVCLAPQIHA AINRFQIDMT 190 200 210 KYPILSRLHD AYMKIPAFQA ALPQNQPDAP SAK

References

[1]

"Isolation of a zeta class wheat glutathione S-transferase gene." Subramaniam K., Ye Z., Buechley G., Shaner G., Solomos T., Ueng P.P. Biochim. Biophys. Acta 1447:348-356(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], CHARACTERIZATION. Strain: cv. Arthur71 and cv. Oasis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF002211 mRNA. Translation: AAB60886.1. AF109714 Genomic DNA. Translation: AAD09190.1.
PIR	T06333.
UniGene	Ta.237.
3D structure databases
ProteinModelPortal	O04437.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	O04437.
Family and domain databases
Gene3D	1.20.1050.10. 1 hit. 3.40.30.10. 1 hit.
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR005955. Mal_ac_isom. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF00043. GST_C. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR01262. maiA. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSTZ_WHEAT

Accession

Primary (citable) accession number: O04437

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	July 1, 1997
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program