Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O04408

- KSA_PEA

UniProt

O04408 - KSA_PEA

Protein

Ent-copalyl diphosphate synthase, chloroplastic

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate.

    Catalytic activityi

    Geranylgeranyl diphosphate = ent-copalyl diphosphate.

    Cofactori

    Magnesium.Curated

    Pathwayi

    GO - Molecular functioni

    1. ent-copalyl diphosphate synthase activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. terpene synthase activity Source: InterPro

    GO - Biological processi

    1. gibberellin biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00390.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ent-copalyl diphosphate synthase, chloroplastic (EC:5.5.1.13)
    Short name:
    Ent-CDP synthase
    Alternative name(s):
    Ent-copalyl diphosphate synthase
    Ent-kaurene synthase A
    Short name:
    KSA
    OrganismiPisum sativum (Garden pea)
    Taxonomic identifieri3888 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 801Ent-copalyl diphosphate synthase, chloroplasticPRO_0000033624
    Transit peptidei1 – ?ChloroplastSequence Analysis

    Structurei

    3D structure databases

    ProteinModelPortaliO04408.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi373 – 3764DXDD motif

    Domaini

    The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity, presumably through binding to Mg2+.

    Sequence similaritiesi

    Belongs to the terpene synthase family.Curated

    Keywords - Domaini

    Transit peptide

    Family and domain databases

    Gene3Di1.10.600.10. 1 hit.
    1.50.10.20. 1 hit.
    1.50.30.10. 1 hit.
    InterProiIPR001906. Terpene_synth_N.
    IPR005630. Terpene_synthase_metal-bd.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    IPR008949. Terpenoid_synth.
    [Graphical view]
    PfamiPF01397. Terpene_synth. 1 hit.
    PF03936. Terpene_synth_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48239. SSF48239. 2 hits.
    SSF48576. SSF48576. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O04408-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFTHFSTHFH LPSSSSLFFL HPFYKSSSLG AVSFVAKDKE KRCRAISKSR    50
    TQEYEGVFQT NVATLKLSEI NVEDVIVIDD EEEQDIRVGL VNKIKSILSS 100
    LEDGEITISA YDTAWVALVE DVNAISTPQF PSSLEWIAKN QLQDGSWGDS 150
    RLFSAHDRII NTLACVIALR SWNMHSEKCD KGMIFFRENL SKLENENEEH 200
    MPIGFEVAFP SLLEGARGIK PLMCPNDSPI LKNIFEKRDE KLTRIPKEIM 250
    HKVPTTLLHS LEGMSGLDWK QLLKLQSQDG SFLFSPSSTA FALMQTKDGN 300
    CLKYLNNVVK KFNGGVPNVY PVDLFEHIWV VDRLERLGIS RFFRHEIKDC 350
    MNYVSKIWSE KGICWARNSN VQDIDDTAMA FRLLRLHGHQ VSAHVFKHFE 400
    RNGEFFCFAG QCTQAVTGMY NLFRASQVLF PGEKILEHAK HFSAKVLKEK 450
    REANELIDKW IIMKNLPEEV GYALDMPWYA NLDRIETRFY IDQYGAESDV 500
    WIGKTLYRMA YVNNNNYLEL AKLDYNNCQA QHLIEWNVIQ TWYLESRLGE 550
    FGLSKRDLLL AYFLATGSIF EPERSHERLA WAKTTALLET IKCYVRNEDL 600
    RKDFAKKFND HIDVRDYSIA RRMKRNKTEH ELVESLFATI GEISWDVRLS 650
    YGHEIGYDMH QCWKKWLSSW QSEGDKCEGE AELLIQIINL CSNHWISEGP 700
    SMQSTIQHLL QLTNSICHKL SCYQKDKELK GISCQENITN SEVESKMQEL 750
    VQMVFQKCPN DIDFNVKNTF FTIAKSFYYA AFCDSRTINF HIAKVLFEKV 800
    V 801
    Length:801
    Mass (Da):92,718
    Last modified:July 1, 1997 - v1
    Checksum:i5CB88ADE00366844
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63652 mRNA. Translation: AAB58822.1.
    PIRiT06783.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63652 mRNA. Translation: AAB58822.1 .
    PIRi T06783.

    3D structure databases

    ProteinModelPortali O04408.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00390 .

    Family and domain databases

    Gene3Di 1.10.600.10. 1 hit.
    1.50.10.20. 1 hit.
    1.50.30.10. 1 hit.
    InterProi IPR001906. Terpene_synth_N.
    IPR005630. Terpene_synthase_metal-bd.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    IPR008949. Terpenoid_synth.
    [Graphical view ]
    Pfami PF01397. Terpene_synth. 1 hit.
    PF03936. Terpene_synth_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48239. SSF48239. 2 hits.
    SSF48576. SSF48576. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A."
      Ait-Ali T., Swain S.M., Reid J.B., Sun T.-P., Kamiya Y.
      Plant J. 11:443-454(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiKSA_PEA
    AccessioniPrimary (citable) accession number: O04408
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3