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Protein

Probable non-specific lipid-transfer protein 2

Gene
N/A
Organism
Parietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandLipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable non-specific lipid-transfer protein 2
Short name:
LTP 2
Alternative name(s):
Allergen Par j II
Major pollen allergen Par j 2.0102
Protein P8
Allergen: Par j 2.0102
OrganismiParietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Taxonomic identifieri33127 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesUrticaceaeParietaria

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE and induces histamine release from basophils of Pj-pollen-allergic subjects.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei507. Par j 2.
509. Par j 2.0102.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000001839932 – 133Probable non-specific lipid-transfer protein 2Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi35 ↔ 83By similarity
Disulfide bondi45 ↔ 60By similarity
Disulfide bondi61 ↔ 106By similarity
Disulfide bondi81 ↔ 121By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliO04403.
SMRiO04403.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the plant LTP family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
PfamiView protein in Pfam
PF00234. Tryp_alpha_amyl. 1 hit.
PRINTSiPR00382. LIPIDTRNSFER.
SMARTiView protein in SMART
SM00499. AAI. 1 hit.
SUPFAMiSSF47699. SSF47699. 1 hit.
PROSITEiView protein in PROSITE
PS00597. PLANT_LTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O04403-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTVSMAALV VIAAALAWTS SAELASAPAP GEGPCGKVVH HIMPCLKFVK
60 70 80 90 100
GEEKEPSKSC CSGTKKLSEE VKTTEQKREA CKCIVAATKG ISGIKNELVA
110 120 130
EVPKKCGITT TLPPITADFD CSKIESTIFR GYY
Length:133
Mass (Da):14,107
Last modified:July 1, 1997 - v1
Checksum:i50DFBB1F7806AF85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95866 mRNA. Translation: CAA65122.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiNLT22_PARJU
AccessioniPrimary (citable) accession number: O04403
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: March 15, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families