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O04403 (NLT22_PARJU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable non-specific lipid-transfer protein 2

Short name=LTP 2
Alternative name(s):
Allergen Par j II
Major pollen allergen Par j 2.0102
Protein P8
Allergen=Par j 2.0102
OrganismParietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Taxonomic identifier33127 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesUrticaceaeParietaria

Protein attributes

Sequence length133 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

Allergenic properties

Causes an allergic reaction in human. Binds to IgE and induces histamine release from basophils of Pj-pollen-allergic subjects.

Sequence similarities

Belongs to the plant LTP family.

Ontologies

Keywords
   Biological processTransport
   DiseaseAllergen
   DomainSignal
   LigandLipid-binding
   PTMDisulfide bond
Gene Ontology (GO)
   Biological_processlipid transport

Inferred from electronic annotation. Source: InterPro

   Molecular_functionlipid binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential
Chain32 – 133102Probable non-specific lipid-transfer protein 2
PRO_0000018399

Amino acid modifications

Disulfide bond35 ↔ 83 By similarity
Disulfide bond45 ↔ 60 By similarity
Disulfide bond61 ↔ 106 By similarity
Disulfide bond81 ↔ 121 By similarity

Sequences

Sequence LengthMass (Da)Tools
O04403 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 50DFBB1F7806AF85

FASTA13314,107
        10         20         30         40         50         60 
MRTVSMAALV VIAAALAWTS SAELASAPAP GEGPCGKVVH HIMPCLKFVK GEEKEPSKSC 

        70         80         90        100        110        120 
CSGTKKLSEE VKTTEQKREA CKCIVAATKG ISGIKNELVA EVPKKCGITT TLPPITADFD 

       130 
CSKIESTIFR GYY 

« Hide

References

[1]Duro G., Colombo P., Costa M.A., Izzo V., Porcasi R., di Fiore R., Locorotondo G., Mirisola M.G., Cocchiara R., Geraci D.
Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Flower.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X95866 mRNA. Translation: CAA65122.1.

3D structure databases

ProteinModelPortalO04403.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome507. Par j 2.
509. Par j 2.0102.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PfamPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSPR00382. LIPIDTRNSFER.
SMARTSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMSSF47699. SSF47699. 1 hit.
PROSITEPS00597. PLANT_LTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNLT22_PARJU
AccessionPrimary (citable) accession number: O04403
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries