ID   FENR2_TOBAC             Reviewed;         375 AA.
AC   O04397;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   16-JUN-2009, entry version 68.
DE   RecName: Full=Ferredoxin--NADP reductase, root-type isozyme, chloroplastic;
DE            Short=FNR;
DE            EC=1.18.1.2;
DE   Flags: Precursor;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Bright Yellow 2;
RA   Kumada H.O., Aoki H., Doyama N., Ida S.;
RT   "Nucleotide sequence of a ferredoxin-NADP+ oxidoreductase cDNA from
RT   cultured tobacco cells.";
RL   (er) Plant Gene Register PGR98-038.
CC   -!- FUNCTION: May play a key role in regulating the relative amounts
CC       of cyclic and non-cyclic electron flow to meet the demands of the
CC       plant for ATP and reducing power. Is involved in nitrate
CC       assimilation.
CC   -!- CATALYTIC ACTIVITY: 2 reduced ferredoxin + NADP(+) + H(+) = 2
CC       oxidized ferredoxin + NADPH.
CC   -!- COFACTOR: FAD.
CC   -!- PATHWAY: Energy metabolism; photosynthesis.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast (By similarity).
CC   -!- SIMILARITY: Belongs to the ferredoxin--NADP reductase type 1
CC       family.
CC   -!- SIMILARITY: Contains 1 FAD-binding FR-type domain.
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DR   EMBL; AB004307; BAA20365.1; -; mRNA.
DR   PIR; T02215; T02215.
DR   HSSP; Q41736; 1JB9.
DR   SMR; O04397; 66-375.
DR   BRENDA; 1.18.1.2; 298.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0042651; C:thylakoid membrane; IEA:InterPro.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050660; F:FAD binding; IEA:InterPro.
DR   GO; GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.
DR   GO; GO:0050661; F:NADP or NADPH binding; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR017927; Fd_Rdtase_FAD-bd.
DR   InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR   InterPro; IPR012146; Frd-NADP+_RD.
DR   InterPro; IPR015701; FRD_Red.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD_bd.
DR   PANTHER; PTHR19384:SF1; FRD_Red; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   PIRSF; PIRSF000361; Frd-NADP+_RD; 1.
DR   PRINTS; PR00371; FPNCR.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Electron transport; FAD; Flavoprotein; NADP;
KW   Oxidoreductase; Photosynthesis; Plastid; Transit peptide; Transport.
FT   TRANSIT       1     60       Chloroplast (Potential).
FT   CHAIN        61    375       Ferredoxin--NADP reductase, root-type
FT                                isozyme, chloroplastic.
FT                                /FTId=PRO_0000019416.
FT   DOMAIN       91    219       FAD-binding FR-type.
FT   NP_BIND     151    154       FAD (By similarity).
FT   NP_BIND     172    174       FAD (By similarity).
FT   NP_BIND     193    195       FAD (By similarity).
FT   NP_BIND     266    267       NADP (By similarity).
FT   NP_BIND     296    297       NADP (By similarity).
FT   NP_BIND     334    335       NADP (By similarity).
FT   BINDING     174    174       NADP (By similarity).
FT   BINDING     178    178       FAD (By similarity).
FT   BINDING     235    235       FAD (By similarity).
FT   BINDING     235    235       NADP; via amide nitrogen (By similarity).
FT   BINDING     306    306       NADP (By similarity).
FT   BINDING     373    373       NADP (By similarity).
SQ   SEQUENCE   375 AA;  41958 MW;  AB5ED3988F746B92 CRC64;
     MAHSALSQVS VAVPLQTDSS FRRSTFKATS ITFSDRSSWI SMPPIDLKAA PSRNQHIVCM
     SVQQASKAKV SVSPLSLEDA KEPPLNIYKP KEPYTATIVS VERLVGPKAP GETCHIVIDH
     DGNLPYWEGQ SYGVIPPGEN PKKPGNPHNV RLYLIASTRY GDSFDGKTAS LCVRRAVYYD
     PETGKEDPSK NGVCSNFLCD SKPGDKVKIT GPSGKIMLLP EEIPNATHIM IGTGTGVAPF
     RGYLRRMFME SVPTKFNGLA WLFLGVANTD SLLYDDEFTK YLNDYPGNFR YDRALSREQK
     NNKGGKMYVQ DKIEEYSDEI FKLLDEGAHI YFCGLKGMMP GIQDTLKRVA ERRGESWEQK
     LSQLKKNKQW HVEVY
//