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Protein

Nuclear transcription factor Y subunit B-4

Gene

NFYB4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi8 – 14By similarity7

GO - Molecular functioni

  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • regulation of transcription, DNA-templated Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear transcription factor Y subunit B-4
Short name:
AtNF-YB-4
Alternative name(s):
Transcriptional activator HAP3D
Gene namesi
Name:NFYB4
Synonyms:HAP3D
Ordered Locus Names:At1g09030
ORF Names:F7G19.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRilocus:2036064. AT1G09030.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002046181 – 139Nuclear transcription factor Y subunit B-4Add BLAST139

Proteomic databases

PaxDbiO04027.

Expressioni

Tissue specificityi

Expressed in flowers, siliques and young rosettes.1 Publication

Gene expression databases

GenevisibleiO04027. AT.

Interactioni

Subunit structurei

Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding (By similarity).By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
PRN1Q9LX492EBI-1751677,EBI-1606661

Protein-protein interaction databases

BioGridi22665. 13 interactors.
IntActiO04027. 1 interactor.
STRINGi3702.AT1G09030.1.

Structurei

3D structure databases

ProteinModelPortaliO04027.
SMRiO04027.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni35 – 46Subunit association domain (SAD)By similarityAdd BLAST12

Sequence similaritiesi

Belongs to the NFYB/HAP3 subunit family.Curated

Phylogenomic databases

eggNOGiKOG0869. Eukaryota.
COG2036. LUCA.
HOGENOMiHOG000211832.
InParanoidiO04027.
OMAiCHRENRK.
OrthoDBiEOG09360PJ1.
PhylomeDBiO04027.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR003958. CBFA_NFYB_domain.
IPR009072. Histone-fold.
IPR003956. Transcrpt_fac_NFYB/HAP3_CS.
PfamiView protein in Pfam
PF00808. CBFD_NFYB_HMF. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00685. NFYB_HAP3. 1 hit.

Sequencei

Sequence statusi: Complete.

O04027-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDEDRLLPI ANVGRLMKQI LPSNAKISKE AKQTVQECAT EFISFVTCEA
60 70 80 90 100
SEKCHRENRK TVNGDDIWWA LSTLGLDNYA DAVGRHLHKY REAERERTEH
110 120 130
NKGSNDSGNE KETNTRSDVQ NQSTKFIRVV EKGSSSSAR
Length:139
Mass (Da):15,741
Last modified:July 1, 1997 - v1
Checksum:i3AF2DD2F0F1DE748
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000106 Genomic DNA. Translation: AAB70405.1.
CP002684 Genomic DNA. Translation: AEE28385.1.
BT029363 mRNA. Translation: ABK32177.1.
PIRiC86222.
RefSeqiNP_172377.1. NM_100774.2.
UniGeneiAt.64828.

Genome annotation databases

EnsemblPlantsiAT1G09030.1; AT1G09030.1; AT1G09030.
GeneIDi837424.
GrameneiAT1G09030.1; AT1G09030.1; AT1G09030.
KEGGiath:AT1G09030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000106 Genomic DNA. Translation: AAB70405.1.
CP002684 Genomic DNA. Translation: AEE28385.1.
BT029363 mRNA. Translation: ABK32177.1.
PIRiC86222.
RefSeqiNP_172377.1. NM_100774.2.
UniGeneiAt.64828.

3D structure databases

ProteinModelPortaliO04027.
SMRiO04027.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi22665. 13 interactors.
IntActiO04027. 1 interactor.
STRINGi3702.AT1G09030.1.

Proteomic databases

PaxDbiO04027.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G09030.1; AT1G09030.1; AT1G09030.
GeneIDi837424.
GrameneiAT1G09030.1; AT1G09030.1; AT1G09030.
KEGGiath:AT1G09030.

Organism-specific databases

AraportiAT1G09030.
TAIRilocus:2036064. AT1G09030.

Phylogenomic databases

eggNOGiKOG0869. Eukaryota.
COG2036. LUCA.
HOGENOMiHOG000211832.
InParanoidiO04027.
OMAiCHRENRK.
OrthoDBiEOG09360PJ1.
PhylomeDBiO04027.

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Miscellaneous databases

PROiO04027.

Gene expression databases

GenevisibleiO04027. AT.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR003958. CBFA_NFYB_domain.
IPR009072. Histone-fold.
IPR003956. Transcrpt_fac_NFYB/HAP3_CS.
PfamiView protein in Pfam
PF00808. CBFD_NFYB_HMF. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00685. NFYB_HAP3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNFYB4_ARATH
AccessioniPrimary (citable) accession number: O04027
Secondary accession number(s): A0JPZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: July 1, 1997
Last modified: February 15, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.