ID   P5CR_ACTCH              Reviewed;         278 AA.
AC   O04016;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   16-JUN-2009, entry version 44.
DE   RecName: Full=Pyrroline-5-carboxylate reductase;
DE            Short=P5C reductase;
DE            Short=P5CR;
DE            EC=1.5.1.2;
OS   Actinidia chinensis (Kiwi) (Yangtao).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   asterids; Ericales; Actinidiaceae; Actinidia.
OX   NCBI_TaxID=3625;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Axillary bud;
RA   Walton E.F., Podivinsky E., Wu R.M., Reynolds P.H.S., Young L.W.;
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: L-proline + NAD(P)(+) = 1-pyrroline-5-
CC       carboxylate + NAD(P)H.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-
CC       proline from L-glutamate 5-semialdehyde: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the pyrroline-5-carboxylate reductase
CC       family.
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DR   EMBL; U92287; AAC14482.1; -; mRNA.
DR   BRENDA; 1.5.1.2; 67098.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR004455; NADP_OxRdtase_F420.
DR   InterPro; IPR000304; P5CR.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11645; P5CR; 1.
DR   Pfam; PF03807; F420_oxidored; 1.
DR   PIRSF; PIRSF000193; Pyrrol-5-carb_rd; 1.
DR   TIGRFAMs; TIGR00112; proC; 1.
DR   PROSITE; PS00521; P5CR; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid biosynthesis; Cytoplasm; NADP; Oxidoreductase;
KW   Proline biosynthesis.
FT   CHAIN         1    278       Pyrroline-5-carboxylate reductase.
FT                                /FTId=PRO_0000187322.
SQ   SEQUENCE   278 AA;  29004 MW;  198B6E934F190236 CRC64;
     MAAAAFVPIP TDTYKLGFIG AGKMAESIAR GVVKSGVLPA SRIRTAHLGS ARREAFESFG
     VKVLDRNDQV VEDSDVIIFS VKPQIVKEVV LQLRPLLSEK QLLVSIVAGV KLKELEDWAG
     HSRFIRVMPN TPAAVGEAAS VMSLGATATG EDGELITKLF GAIGKIWKAD EKLFDAVTGL
     SGSGPAYIFL AIEALADGGV AAGLPRELAL GLASQTVLGA ASMVARGGKH PGQLKDDVAS
     AGGTTIAGIH ELEKGGFRGT LMNAVVSATK RSQEIFKR
//