Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Non-specific lipid-transfer protein

Gene
N/A
Organism
Ambrosia artemisiifolia (Short ragweed)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific lipid-transfer protein
Short name:
LTP
Alternative name(s):
Allergen Amb a VI
Allergen Ra6
Pollen allergen Amb a 6
Allergen: Amb a 6
OrganismiAmbrosia artemisiifolia (Short ragweed)
Taxonomic identifieri4212 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceHeliantheaeAmbrosia

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei29. Amb a 6.
3070. Amb a 6.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 251 PublicationAdd BLAST25
ChainiPRO_000001836026 – 118Non-specific lipid-transfer proteinAdd BLAST93

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 76By similarity
Disulfide bondi40 ↔ 53By similarity
Disulfide bondi54 ↔ 98By similarity
Disulfide bondi74 ↔ 113By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliO04004.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the plant LTP family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00382. LIPIDTRNSFER.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O04004-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDCIRILWSV AVGLLLVSWR PTMFAASPTC DTVQNILAPC AGFLTGQEPS
60 70 80 90 100
KACCTGVNNL NNSRKTKADR VAVCNCIKEL TKSIAYDPKR MPLLSTKCGV
110
KPDFPAVDKN LDCSKLPV
Length:118
Mass (Da):12,789
Last modified:July 1, 1997 - v1
Checksum:i59356E9196C0CD38
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti26Missing in Ra6B. 1 Publication1
Natural varianti27S → P in Ra6A. 2 Publications1
Natural varianti32T → A in Ra6B. 1 Publication1
Natural varianti32T → D.1 Publication1
Natural varianti36I → N in Ra6A. 2 Publications1
Natural varianti67K → P.1 Publication1
Natural varianti71V → M.1 Publication1
Natural varianti91M → V.1 Publication1
Natural varianti111L → F.1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89793 mRNA. Translation: AAB51146.1.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89793 mRNA. Translation: AAB51146.1.

3D structure databases

ProteinModelPortaliO04004.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei29. Amb a 6.
3070. Amb a 6.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00382. LIPIDTRNSFER.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNLTP6_AMBAR
AccessioniPrimary (citable) accession number: O04004
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: July 1, 1997
Last modified: October 1, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.