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Protein

NADH-ubiquinone oxidoreductase chain 5

Gene

nad5

Organism
Vicia faba (Broad bean) (Faba vulgaris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Keywords - Ligandi

NADUniRule annotation, UbiquinoneUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 5UniRule annotation (EC:1.6.5.3UniRule annotation)
Gene namesi
Name:nad5Imported
Encoded oniMitochondrionImported
OrganismiVicia faba (Broad bean) (Faba vulgaris)Imported
Taxonomic identifieri3906 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaeVicia

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei83 – 101HelicalSequence analysisAdd BLAST19
Transmembranei113 – 130HelicalSequence analysisAdd BLAST18
Transmembranei136 – 155HelicalSequence analysisAdd BLAST20
Transmembranei215 – 231HelicalSequence analysisAdd BLAST17
Transmembranei251 – 270HelicalSequence analysisAdd BLAST20
Transmembranei282 – 304HelicalSequence analysisAdd BLAST23
Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Transmembranei342 – 359HelicalSequence analysisAdd BLAST18
Transmembranei379 – 399HelicalSequence analysisAdd BLAST21
Transmembranei420 – 443HelicalSequence analysisAdd BLAST24
Transmembranei463 – 481HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500415663117 – 483NADH-ubiquinone oxidoreductase chain 5Sequence analysisAdd BLAST467

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 118Proton_antipo_NInterPro annotationAdd BLAST56
Domaini132 – 419Proton_antipo_MInterPro annotationAdd BLAST288

Sequence similaritiesi

Belongs to the complex I subunit 5 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiIPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
IPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.

Sequencei

Sequence statusi: Complete.

O03386-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLLIVFLPL LGSSVAGFFG RFLGSEGTAI MTTTCVSFSS ILSLIAFYEV
60 70 80 90 100
APGASACYLR IAPWISSEMF DASWGFLFDS PTVVMLIVVT SISSLVHLYS
110 120 130 140 150
ISYMSEDPHS PRFMCYLSIL TFFMPMLVTG DNSLQLFLGW EGVGLASYLL
160 170 180 190 200
IHFWFTRLQA DKAATKAMPV NRVGDFGLAP GISGRFTLFQ TVDFSTIFAR
210 220 230 240 250
ASAPRNSWIS CNMRLNAISL ICILLLIGAV GKSAQIGSHT WSPDAMEGPT
260 270 280 290 300
PVSALIHAAT MVTAGVFMIA RCSPLFEYPP TALIVITSAG ATTSFLAATT
310 320 330 340 350
GILQNDLKRV IAYSTCSQLG YMIFACGISN YSVSVFHLMN HAFFKALLFL
360 370 380 390 400
SAGSVIHAMS DEQDMRKMGG LASSFPFTYA MMLMGSLSLI GFPFLTGFYS
410 420 430 440 450
KDVILELAYT KYTISGNFAF WLGSVSVLFT SYYSFRSLFL TFLVPTNSFG
460 470 480
RDILRCHDAP IPMAIPLILL ALGSLFVGYL AKV
Length:483
Mass (Da):52,617
Last modified:July 1, 1997 - v1
Checksum:i57F57DE1286EDC04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12731 Genomic DNA. Translation: CAA73263.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12731 Genomic DNA. Translation: CAA73263.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
IPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO03386_VICFA
AccessioniPrimary (citable) accession number: O03386
Secondary accession number(s): O03249
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.