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Protein
Submitted name:

ArfGAP with dual PH domains 1

Gene

ADAP1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ArfGAP with dual PH domains 1Imported
Submitted name:
Phosphatidylinositol-3,4,5-triphosphate binding proteinImported
Gene namesi
Name:ADAP1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Organism-specific databases

VGNCiVGNC:25633 ADAP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000015952

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052493

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 126Arf-GAPInterPro annotationAdd BLAST120
Domaini129 – 230PHInterPro annotationAdd BLAST102
Domaini252 – 355PHInterPro annotationAdd BLAST104

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0703 Eukaryota
COG5347 LUCA
GeneTreeiENSGT00900000140892
HOGENOMiHOG000006719
HOVERGENiHBG050888
OMAiEAQVEFM
OrthoDBiEOG091G0789
TreeFamiTF324540

Family and domain databases

CDDicd13252 PH1_ADAP, 1 hit
cd01251 PH2_ADAP, 1 hit
Gene3Di2.30.29.30, 2 hits
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR037849 PH1_ADAP
IPR037851 PH2_ADAP
IPR001849 PH_domain
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 2 hits
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 2 hits

Sequencei

Sequence statusi: Complete.

O02753-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKERRKAVL ELLQRPGNAR CADCGAPDPD WASYTLGVFI CLSCSGIHRN
60 70 80 90 100
IPHVSKVKSV RLDTWEDVQV EFMASRGNAI ARATFESRVP PFYYRPSASD
110 120 130 140 150
CPLLREQWIR AKYERQEFAH PERQEPYSAG YREGFLWKRG RDNGQFLSRK
160 170 180 190 200
FVLTEREGAL KYFNRSDAKE PKAVMKIEHL NATFQPAKIG HPHGLQVTYL
210 220 230 240 250
KDNSTRNIFV YHEDGKEMVD WFNALRAARF HYLQVAFPGA SNADLVPKLS
260 270 280 290 300
RNYLQEGYME KTGPKTEGFR KRWFTMDDRR LMYFKDPLDA FARGEVFIGS
310 320 330 340 350
RESGYTVLDG LPPSTQGHHW PHGITIVTPE RRFLLACETE SEQRAWMEAL
360 370
QKVVDRPMLP QEYAVEAHFK HKP
Length:373
Mass (Da):43,207
Last modified:July 1, 1997 - v1
Checksum:i4FE856D1C0E82B06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02058420 Genomic DNA No translation available.
D89940 mRNA Translation: BAA20132.1
RefSeqiNP_776938.1, NM_174513.2
UniGeneiBt.62790

Genome annotation databases

EnsembliENSBTAT00000053527; ENSBTAP00000052493; ENSBTAG00000015952
GeneIDi282176
KEGGibta:282176

Similar proteinsi

Entry informationi

Entry nameiO02753_BOVIN
AccessioniPrimary (citable) accession number: O02753
Secondary accession number(s): F1N5G2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health