O02724 (O02724_SHEEP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Pregnancy-associated glycoprotein 4 EMBL AAB53225.1
Organism	Ovis aries (Sheep) EMBL AAB53225.1
Taxonomic identifier	9940 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Caprinae › Ovis

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase A1 family. RuleBase RU000454

Ontologies

Keywords
Molecular function	Aspartyl protease RuleBase RU000454 SAAS SAAS012848 Hydrolase Protease
PTM	Disulfide bond SAAS SAAS012848
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O02724 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: D58242542B624283	FASTA	380	42,762
	10 20 30 40 50 60 MKWLVLLGLV AFSECIFKIP LRRVKTMRKT LSGKNMLNDV LKEHPYRLPQ ISFRGSNLII 70 80 90 100 110 120 HPLRNIRDTF YVGNITIGTP PQEFQVLFDT GSSVLWVPSV LCNSSTCSIH VRFRHLQSST 130 140 150 160 170 180 FRTTNKTFWI TYGAGTMKGV VAHDTVRIGD LVSIDQPFGL SMAEYGFHGR RFDGVLGLNY 190 200 210 220 230 240 PRQSCCRPTP IFDKLKNQGA ISEPVFAFYL SKDEQEGSVV MFGGVDHRYY KGELNWVPLV 250 260 270 280 290 300 KADDWTIQVD RISMRREVIA CSDGCDALLD TGASFIHGPG RLIDDIQKLI GSEPRDLKHY 310 320 330 340 350 360 ISCSAVNTLP SIIFTINGIN YPVPAQAYIL KGSTGHCYTA FRAKRVRTST ESWVLGDVFL 370 380 RLYFSVFDRG NDRIGLAPAM

References

[1]	"Identification of the major pregnancy-specific antigens of cattle and sheep as inactive members of the aspartic proteinase family." Xie S., Low B.G., Nagel R.J., Kramer K.K., Anthony R.V., Zoli A.P., Beckers J.-F.M.P., Roberts R.M. Proc. Natl. Acad. Sci. U.S.A. 88:10247-10251(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL AAB53225.1.
[2]	Xie S., Green J., Valdez K., Roberts R.M. Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL AAB53225.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U94790 mRNA. Translation: AAB53225.1.
RefSeq	NP_001009462.1. NM_001009462.1.
UniGene	Oar.536.
3D structure databases
HSSP	HSSP built from PDB template 4CMS based on UniProtKB P00794.
ProteinModelPortal	O02724.
ModBase	Search...
Protein family/group databases
MEROPS	A01.971.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	443536.
Organism-specific databases
CTD	337898.
Phylogenomic databases
HOVERGEN	HBG000482.
Family and domain databases
Gene3D	2.40.70.10. 2 hits.
InterPro	IPR001461. Peptidase_A1. IPR021109. Peptidase_aspartic. IPR001969. Peptidase_aspartic_AS. IPR012848. Propep_A1. [Graphical view]
PANTHER	PTHR13683. PTHR13683. 1 hit.
Pfam	PF07966. A1_Propeptide. 1 hit. PF00026. Asp. 1 hit. [Graphical view]
PRINTS	PR00792. PEPSIN.
SUPFAM	SSF50630. Pept_Aspartic. 1 hit.
PROSITE	PS00141. ASP_PROTEASE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O02724_SHEEP

Accession

Primary (citable) accession number: O02724

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)