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Protein

Serine/threonine-protein phosphatase

Gene

gsp-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

  • male meiosis chromosome segregation Source: WormBase
  • oviposition Source: WormBase
  • regulation of pseudopodium assembly Source: WormBase
  • reproduction Source: WormBase
  • sperm motility Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphataseSAAS annotation

Keywords - Ligandi

ManganeseSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:gsp-3Imported
ORF Names:CELE_W09C3.6Imported, W09C3.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiW09C3.6; CE14754; WBGene00021113; gsp-3.

Subcellular locationi

GO - Cellular componenti

  • chromatin Source: WormBase
  • cytoplasm Source: WormBase
  • nuclear chromatin Source: WormBase
  • pseudopodium Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO02658.
PaxDbiO02658.
PRIDEiO02658.

Expressioni

Gene expression databases

ExpressionAtlasiO02658. baseline.

Interactioni

Protein-protein interaction databases

DIPiDIP-27281N.
MINTiMINT-1115524.
STRINGi6239.W09C3.6.

Structurei

3D structure databases

ProteinModelPortaliO02658.
SMRiO02658. Positions 5-297.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini119 – 1246SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO02658.
KOiK01090.
OMAiCCTVAKS.
OrthoDBiEOG722JDC.
PhylomeDBiO02658.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR031675. STPPase_N.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF16891. STPPase_N. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O02658-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPMDVDNL MSRLLNVGMS GGRLTTSVNE QELQTCCAVA KSVFASQASL
60 70 80 90 100
LEVEPPIIVC GDIHGQYSDL LRIFDKNGFP PDVNFLFLGD YVDRGRQNIE
110 120 130 140 150
TICLMLCFKI KYPENFFMLR GNHECPAINR VYGFYEECNR RYKSTRLWSI
160 170 180 190 200
FQDTFNWMPL CGLIGSRILC MHGGLSPHLQ TLDQLRQLPR PQDPPNPSIG
210 220 230 240 250
IDLLWADPDQ WVKGWQANTR GVSYVFGQDV VADVCSRLDI DLVARAHQVV
260 270 280 290 300
QDGYEFFASK KMVTIFSAPH YCGQFDNSAA TMKVDENMVC TFVMYKPTPK

SMRRG
Length:305
Mass (Da):34,596
Last modified:July 1, 1997 - v1
Checksum:i1D503E11DE0A5B6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD64235.1.
PIRiT34462.
RefSeqiNP_491429.1. NM_059028.3.

Genome annotation databases

EnsemblMetazoaiW09C3.6; W09C3.6; WBGene00021113.
GeneIDi172082.
KEGGicel:CELE_W09C3.6.
UCSCiW09C3.6. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD64235.1.
PIRiT34462.
RefSeqiNP_491429.1. NM_059028.3.

3D structure databases

ProteinModelPortaliO02658.
SMRiO02658. Positions 5-297.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-27281N.
MINTiMINT-1115524.
STRINGi6239.W09C3.6.

Proteomic databases

EPDiO02658.
PaxDbiO02658.
PRIDEiO02658.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW09C3.6; W09C3.6; WBGene00021113.
GeneIDi172082.
KEGGicel:CELE_W09C3.6.
UCSCiW09C3.6. c. elegans.

Organism-specific databases

CTDi172082.
WormBaseiW09C3.6; CE14754; WBGene00021113; gsp-3.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO02658.
KOiK01090.
OMAiCCTVAKS.
OrthoDBiEOG722JDC.
PhylomeDBiO02658.

Miscellaneous databases

NextBioi873941.

Gene expression databases

ExpressionAtlasiO02658. baseline.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR031675. STPPase_N.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
PF16891. STPPase_N. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO02658_CAEEL
AccessioniPrimary (citable) accession number: O02658
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.