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Protein

Alpha-amylase

Gene

Amy II

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:Amy IIImported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500415753819 – 486Alpha-amylaseSequence analysisAdd BLAST468

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL008451-PA.

Structurei

3D structure databases

ProteinModelPortaliO02652.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 393AamyInterPro annotationAdd BLAST365
Domaini402 – 486Aamy_CInterPro annotationAdd BLAST85

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2212. Eukaryota.
COG0366. LUCA.
HOGENOMiHOG000253313.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

O02652-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILASFLAV AFATLVSAQF DTHQWADRSG IVHLFEWRWN DIADECERFL
60 70 80 90 100
APRGYAGVQV SPPTENIIVS GRPWWERYQP ASYHLNTRSG SEAEFASMVR
110 120 130 140 150
RCNNVGVRIY VDIVINHMAA ISGQGTGGSQ VNGLNFPAVP YGANDFNPHC
160 170 180 190 200
EINNYNDPYQ VRNCWLVGLP DLALGTQWVR DRIVDLMNKC IGYGIAGFRV
210 220 230 240 250
DAVKHMWPGD LEHIYNRLNN LNTDHGFPGG ARPFITQEVI DLGGEAISKY
260 270 280 290 300
EYTHLGTVTE FRYSAEIGRV FHGRDRLAHL SNWGEQWGFL PSHLGLAFVD
310 320 330 340 350
NHDNQRGHGA GGDNVLTHKT PKNYKIGSAF MLAHPYGIIR VMSSFFFDNG
360 370 380 390 400
DQGPPQDGNG NLIPPSINAD NSCGNGWACE HRWRQIYNMV GFRNAVRGTG
410 420 430 440 450
INDWWSNGNQ QIAFCRGGSG FVAFNLEGYD MNENLQTCLS AGTYCDVISG
460 470 480
SKEGGSSLVL QCKSVEMDVP ISIFRPKVMM VFWPSM
Length:486
Mass (Da):54,188
Last modified:July 1, 1997 - v1
Checksum:i0630292396FF25F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000568 Genomic DNA. Translation: AAB60934.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000568 Genomic DNA. Translation: AAB60934.1.

3D structure databases

ProteinModelPortaliO02652.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL008451-PA.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG2212. Eukaryota.
COG0366. LUCA.
HOGENOMiHOG000253313.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO02652_AEDAE
AccessioniPrimary (citable) accession number: O02652
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.